CHMP5 and APPBP2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHMP5	APPBP2
Gene Name		charged multivesicular body protein 5	amyloid beta precursor protein (cytoplasmic tail) binding protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Endosome Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Protein Binding	Microtubule Motor Activity Protein Binding
	Biological Process	Cell Separation After Cytokinesis Regulation Of Receptor Recycling Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Membrane Organization Regulation Of Mitotic Spindle Assembly	Intracellular Protein Transport Metabolic Process Intracellular Transport
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS		Erectile dysfunction and prostate cancer treatment ( 20932654)
Protein-Protein Interactions		15 interactors: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91	79 interactors: AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 DCD DHRS2 DPEP1 EID3 EPT1 ERO1L FAM19A4 FAM92A1 FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 HIPK4 HIST1H2AK HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MGC34796 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		51510	10513
HPRD ID		15408	05616
Ensembl ID		ENSG00000086065	ENSG00000062725
Uniprot IDs		Q9NZZ3	Q92624
PDB IDs		2LXM 3ULY 3UM0 3UM1 3UM2
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Establishment Of Chromosome Localization Viral Budding Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Viral Life Cycle Cell Division Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Virion Assembly Nucleus Organization Negative Regulation Of Autophagic Vacuole Assembly Establishment Of Organelle Localization Mitotic Cell Cycle Process Regulation Of Centrosome Duplication Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Centrosome Cycle Mitotic Cell Cycle Organelle Localization Endosomal Transport Cell Cycle Posttranslational Protein Targeting To Membrane Positive Regulation Of Viral Release From Host Cell Establishment Of Localization In Cell Protein Transport Chromosome Segregation Positive Regulation Of Viral Process Establishment Of Protein Localization Vacuolar Transport Viral Process Membrane Budding Intracellular Transport Cell Cycle Process Negative Regulation Of Macroautophagy Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Localization Mitotic Nuclear Division Cytokinesis Regulation Of Autophagic Vacuole Assembly Regulation Of Mitotic Nuclear Division Regulation Of Vacuole Organization Protein Localization To Endoplasmic Reticulum Protein Localization Regulation Of Viral Release From Host Cell Regulation Of Microtubule Cytoskeleton Organization	Regulation Of Defense Response To Virus By Host Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Homocysteine Metabolic Process Cellular Response To Organic Substance
Tagcloud ?		associate avian beyond budding coactivator conjugation dimer e3 endosome escrt evolved fusions gag hexamer homologue inability interferes isg15 leukosis lip5 probable rescued retroviruses sarcoma scission sorting tsg101 ubiquitin vps4	10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?		associate avian beyond budding coactivator conjugation dimer e3 endosome escrt evolved fusions gag hexamer homologue inability interferes isg15 leukosis lip5 probable rescued retroviruses sarcoma scission sorting tsg101 ubiquitin vps4	10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?