CHMP5 and PDCD10

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
HPRD (two hybrid)

		CHMP5	PDCD10
Gene Name		charged multivesicular body protein 5	programmed cell death 10
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Endosome Membrane Extracellular Vesicular Exosome	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding Protein Homodimerization Activity Protein N-terminus Binding
	Biological Process	Cell Separation After Cytokinesis Regulation Of Receptor Recycling Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Membrane Organization Regulation Of Mitotic Spindle Assembly	Angiogenesis Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Rho Protein Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Stress Fiber Assembly Positive Regulation Of MAP Kinase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Notch Signaling Pathway Protein Stabilization Establishment Of Golgi Localization Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Golgi Reassembly Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS		Erectile dysfunction and prostate cancer treatment ( 20932654)
Protein-Protein Interactions		15 interactors: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91	5 interactors: C4orf19 CHMP5 STK24 STK25 STK26
Entrez ID		51510	11235
HPRD ID		15408	10141
Ensembl ID		ENSG00000086065	ENSG00000114209
Uniprot IDs		Q9NZZ3	Q9BUL8
PDB IDs		2LXM 3ULY 3UM0 3UM1 3UM2	3AJM 3L8I 3L8J 3RQE 3RQF 3RQG 3W8H 3W8I 4GEH
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Establishment Of Chromosome Localization Viral Budding Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Viral Life Cycle Cell Division Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Virion Assembly Nucleus Organization Negative Regulation Of Autophagic Vacuole Assembly Establishment Of Organelle Localization Mitotic Cell Cycle Process Regulation Of Centrosome Duplication Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Centrosome Cycle Mitotic Cell Cycle Organelle Localization Endosomal Transport Cell Cycle Posttranslational Protein Targeting To Membrane Positive Regulation Of Viral Release From Host Cell Establishment Of Localization In Cell Protein Transport Chromosome Segregation Positive Regulation Of Viral Process Establishment Of Protein Localization Vacuolar Transport Viral Process Membrane Budding Intracellular Transport Cell Cycle Process Negative Regulation Of Macroautophagy Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Localization Mitotic Nuclear Division Cytokinesis Regulation Of Autophagic Vacuole Assembly Regulation Of Mitotic Nuclear Division Regulation Of Vacuole Organization Protein Localization To Endoplasmic Reticulum Protein Localization Regulation Of Viral Release From Host Cell Regulation Of Microtubule Cytoskeleton Organization	Response To Hydrogen Peroxide Response To Reactive Oxygen Species Protein Autophosphorylation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Response To Oxidative Stress Response To Inorganic Substance Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Apoptotic Process Programmed Cell Death Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Cell Death Death Intrinsic Apoptotic Signaling Pathway Cellular Response To Oxidative Stress Golgi Reassembly Protein Phosphorylation Signal Transduction By Phosphorylation Establishment Of Golgi Localization Establishment Of Organelle Localization Golgi Inheritance Apoptotic Signaling Pathway Regulation Of Mitotic Spindle Assembly Regulation Of Neuron Projection Development Golgi Localization Regulation Of Spindle Assembly Organelle Localization Phosphorylation Regulation Of Cellular Component Organization Regulation Of Hydrogen Peroxide-induced Cell Death Regulation Of Mitotic Spindle Organization Regulation Of Cell Projection Organization Microvillus Assembly Microvillus Organization Regulation Of Neuron Differentiation Regulation Of Axon Regeneration Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Regulation Of Receptor Recycling Regulation Of Neurogenesis Regulation Of Response To Reactive Oxygen Species Endosome To Lysosome Transport Metaphase Plate Congression Phosphate-containing Compound Metabolic Process Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Cell Development Lysosomal Transport Regulation Of Centrosome Cycle Regulation Of Cellular Response To Oxidative Stress
Tagcloud ?		associate avian beyond budding coactivator conjugation dimer e3 endosome escrt evolved fusions gag hexamer homologue inability interferes isg15 leukosis lip5 probable rescued retroviruses sarcoma scission sorting tsg101 ubiquitin vps4	4b adriamycin ataxia carboplatin coded ct cyclophosphamide desirable eif4b isoaspartate matr3 matrin meiotic microrchidia morc3 pbl pbls pcmtd2 personalised psmb1 rmnd5a runt runx2 sacm1l subtraction telangiectasia tmem66 undesired znf644
Tagcloud (Difference) ?		associate avian beyond budding coactivator conjugation dimer e3 endosome escrt evolved fusions gag hexamer homologue inability interferes isg15 leukosis lip5 probable rescued retroviruses sarcoma scission sorting tsg101 ubiquitin vps4	4b adriamycin ataxia carboplatin coded ct cyclophosphamide desirable eif4b isoaspartate matr3 matrin meiotic microrchidia morc3 pbl pbls pcmtd2 personalised psmb1 rmnd5a runt runx2 sacm1l subtraction telangiectasia tmem66 undesired znf644
Tagcloud (Intersection) ?