CHMP5 and PDCD10

Number of citations of the paper that reports this interaction (PubMedID 16730941)
0

Data Source:
HPRD (two hybrid)

		CHMP5	PDCD10
Description		charged multivesicular body protein 5	programmed cell death 10
Image
GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore ESCRT III Complex Nucleus Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Membrane Midbody Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Extracellular Exosome FAR/SIN/STRIPAK Complex
	Molecular Function	Protein Binding Cadherin Binding	Protein Binding Protein Kinase Binding Protein Homodimerization Activity
	Biological Process	Plasma Membrane Repair Regulation Of Receptor Recycling Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Lysosome Organization Mitotic Metaphase Chromosome Alignment Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Erythrocyte Differentiation Nuclear Membrane Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Viral Budding From Plasma Membrane Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport ESCRT III Complex Disassembly	Angiogenesis Endothelium Development Apoptotic Process Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Rho Protein Signal Transduction Intracellular Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Stress Fiber Assembly Positive Regulation Of MAP Kinase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Notch Signaling Pathway Regulation Of Angiogenesis Protein Stabilization Establishment Of Golgi Localization Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Golgi Reassembly Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Cellular Response To Leukemia Inhibitory Factor
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases			Cerebral cavernous malformation
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction and prostate cancer treatment ( 20932654)	Fast beta electroencephalogram ( 28070124) Platelet count ( 32888494)
Interacting Genes		17 interacting genes: APPBP2 CEBPA CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91	9 interacting genes: CHMP5 FAM118B FARSA FRYL MINAR1 PLEKHS1 STK24 STK25 STRN
Entrez ID		51510	11235
HPRD ID		15408	10141
Ensembl ID		ENSG00000086065	ENSG00000114209
Uniprot IDs		Q9NZZ3	Q9BUL8
PDB IDs		2LXM 3ULY 3UM0 3UM1 3UM2 4TXR	3AJM 3L8I 3L8J 3RQE 3RQF 3RQG 3W8H 3W8I 4GEH 4TVQ
Enriched GO Terms of Interacting Partners?		Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Midbody Abscission Mitotic Cytokinetic Process Viral Budding Multivesicular Body Assembly Multivesicular Body Organization Late Endosome To Vacuole Transport Cytokinetic Process Viral Budding From Plasma Membrane Endosome Transport Via Multivesicular Body Sorting Pathway Late Endosome To Lysosome Transport Protein-containing Complex Disassembly Regulation Of Mitotic Spindle Assembly Nuclear Membrane Reassembly Chromosome Localization Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Release From Host Cell Endosome Organization Nuclear Pore Nucleus Organization Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization ESCRT III Complex Disassembly ESCRT Complex Disassembly Membrane Fission Mitotic Metaphase Chromosome Alignment ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Multivesicular Body Nuclear Membrane Organization Multivesicular Body-lysosome Fusion Autophagosome Maturation Lysosomal Membrane Organization Metaphase Chromosome Alignment Membrane Assembly Viral Process Late Endosome Membrane Autophagy Kinetochore Endosome Vacuolar Transport Kinetochore Microtubule Midbody Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Membrane Membrane Coat Endosomal Transport	FAR/SIN/STRIPAK Complex Regulation Of Neuron Projection Development Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Mitotic Cytokinetic Process Cytokinetic Process Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Mitotic Cleavage Furrow Formation
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