VPS18 and MON1B

Number of citations of the paper that reports this interaction (PubMedID 20434987)
0

Data Source:
BioGRID (two hybrid, pull down)

		VPS18	MON1B
Description		VPS18 core subunit of CORVET and HOPS complexes	MON1 vesicular trafficking associated B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Actin Filament Endosome Membrane Endomembrane System Membrane AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Cytoplasmic Vesicle Late Endosome Membrane CORVET Complex Presynapse Glutamatergic Synapse	Cytoplasm Mon1-Ccz1 Complex
	Molecular Function	Actin Binding Protein Binding Zinc Ion Binding Syntaxin Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Vesicle-mediated Transport Protein Ubiquitination Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Symbiont Entry Into Host Cell Organelle Fusion Regulation Of Synaptic Vesicle Exocytosis	Protein Targeting To Vacuole Vesicle-mediated Transport Early Viral Transcription Late Viral Transcription
Pathways		SARS-CoV-2 modulates autophagy	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Hemoglobin ( 32888494) Malaria ( 31844061) Refractive error ( 32231278) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Antidepressant treatment resistance (> 2 drugs prescribed) ( 30700811) Immune response to measles-mumps-rubella vaccine ( 24811271) Metabolite levels ( 23823483) Multisite chronic pain ( 31194737 33830993) Number of sexual partners ( 30643258)
Interacting Genes		22 interacting genes: AKTIP COPB1 EP300 GGA1 GGA2 GGA3 HOOK1 MON1B PLEKHM1 RAB7A RILP SHANK3 STX1A STX6 STX7 STX8 UBE2D2 UVRAG VPS11 VPS16 VPS33A VPS45	6 interacting genes: RABGEF1 VPS11 VPS16 VPS18 VPS33A VPS41
Entrez ID		57617	22879
HPRD ID		09776	12342
Ensembl ID		ENSG00000104142	ENSG00000103111
Uniprot IDs		Q9P253	B4DKA0 E7EW32 Q6ZR87 Q7L1V2
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Transport Intracellular Protein Localization Vesicle-mediated Transport Intracellular Transport Cellular Localization Establishment Of Localization In Cell Establishment Of Protein Localization Intracellular Protein Transport Endosome Vesicle Organization Vesicle Fusion Organelle Membrane Fusion Vacuolar Transport Lysosomal Transport Organelle Fusion Membrane Fusion Late Endosome Endosome To Lysosome Transport Endosome Membrane Early Endosome HOPS Complex Endosomal Transport Early Endosome To Late Endosome Transport Membrane Organization Lysosome Late Endosome Membrane Membrane Docking Cytoplasmic Vesicle Organelle Localization Vesicle Docking Lysosomal Membrane SNARE Binding Recycling Endosome Organelle Organization Clathrin-coated Vesicle Organelle Localization By Membrane Tethering Chloride Channel Inhibitor Activity Endosome Organization CORVET Complex Phagocytic Vesicle Vacuole Organization SNAP Receptor Activity SNARE Complex Syntaxin Binding Vesicle-mediated Transport To The Plasma Membrane Establishment Of Protein Localization To Plasma Membrane Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Golgi Vesicle Transport Autophagy	Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion HOPS Complex CORVET Complex Endosome To Lysosome Transport Clathrin-coated Vesicle Vesicle Fusion Organelle Membrane Fusion Early Endosome Lysosomal Transport Organelle Fusion Late Endosome Membrane Late Endosome Membrane Fusion Vacuolar Transport AP-3 Adaptor Complex Endosome Endosome Membrane Autophagosome Autophagy Vesicle Organization Lysosomal Membrane Regulation Of Protein-containing Complex Assembly Protein Transport Vesicle-mediated Transport Lysosome Intracellular Transport Establishment Of Protein Localization Intracellular Protein Transport Membrane Organization Cellular Localization Establishment Of Localization In Cell Vesicle Tethering Complex Intracellular Protein Localization Cytoplasmic Vesicle Clathrin Complex Organelle Localization Regulation Of Cellular Component Organization Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Vacuole Organization Regulation Of Intracellular Estrogen Receptor Signaling Pathway Vesicle Docking Involved In Exocytosis Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Catabolic Process Syntaxin Binding Autophagosome Maturation Lysosome Localization Ubiquitin Protein Ligase Activity Vesicle Docking Endocytic Vesicle
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