GLOD4 and LTB4R2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		GLOD4	LTB4R2
Description		glyoxalase domain containing 4	leukotriene B4 receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Extracellular Exosome	Nucleoplasm Plasma Membrane Membrane
	Molecular Function	Cadherin Binding	Leukotriene B4 Receptor Activity G Protein-coupled Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process		Chemotaxis Signal Transduction G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Keratinocyte Migration Leukotriene Signaling Pathway
Pathways			Leukotriene receptors G alpha (q) signalling events
Drugs			Amelubant Leukotriene B4
Diseases
GWAS		Prostate cancer ( 23535732)	Anorectal malformation ( 31136621) Height ( 28552196)
Interacting Genes		6 interacting genes: APP BCL2L1 LTB4R2 NR4A1 NUDT9 PNRC2	46 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MYO1E OBSL1 P4HTM PER1 PIGM PKD1 RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B
Entrez ID		51031	56413
HPRD ID		12678	16153
Ensembl ID		ENSG00000167699	ENSG00000213906
Uniprot IDs		B3KV49 B7Z403 Q9HC38	B4E292 Q9NPC1
PDB IDs		3ZI1
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Macrophage Activation Amylin Binding Chemotaxis Positive Regulation Of Toll Signaling Pathway Locomotion Apoptotic Process In Bone Marrow Cell Nuclear Membrane Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Apoptotic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Programmed Cell Death Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Lipoprotein Particle Myeloid Leukocyte Activation Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Mitochondrion Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Dendritic Cell Proliferation Dendritic Cell Apoptotic Process ADP-sugar Diphosphatase Activity Leukotriene B4 Receptor Activity Leukotriene Receptor Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Response To Cycloheximide Detection Of Lipopolysaccharide Cellular Response To Corticotropin-releasing Hormone Stimulus ADP-ribose Diphosphatase Activity Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Leukotriene Signaling Pathway	Endoplasmic Reticulum Membrane Endoplasmic Reticulum Membrane Extracellular Exosome Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Vesicle Oligosaccharyltransferase Complex B
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