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GLOD4 and BCL2L1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
GLOD4
BCL2L1
Gene Name
glyoxalase domain containing 4
BCL2-like 1
Image
Gene Ontology Annotations
Cellular Component
Mitochondrion
Extracellular Vesicular Exosome
Nucleus
Nucleolus
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Mitochondrial Inner Membrane
Mitochondrial Matrix
Centrosome
Cytosol
Integral Component Of Membrane
Cell Junction
Synaptic Vesicle Membrane
Nuclear Membrane
Bcl-2 Family Protein Complex
Molecular Function
Protein Binding
Protein Kinase Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
BH3 Domain Binding
Biological Process
Cytokinesis
Ovarian Follicle Development
In Utero Embryonic Development
Release Of Cytochrome C From Mitochondria
Endocytosis
Apoptotic Process
Mitotic Cell Cycle Checkpoint
Germ Cell Development
Spermatogenesis
Cell Proliferation
Positive Regulation Of Cell Proliferation
Male Gonad Development
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Apoptotic Mitochondrial Changes
Fertilization
Negative Regulation Of Autophagy
Suppression By Virus Of Host Apoptotic Process
Response To Cytokine
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Growth
Negative Regulation Of Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Innate Immune Response
Response To Cycloheximide
Regulation Of Mitochondrial Membrane Permeability
Neuron Apoptotic Process
Regulation Of Mitochondrial Membrane Potential
Cellular Process Regulating Host Cell Cycle In Response To Virus
Mitochondrion Morphogenesis
Cellular Response To Amino Acid Stimulus
Cellular Response To Alkaloid
Cellular Response To Gamma Radiation
Apoptotic Process In Bone Marrow
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Negative Regulation Of Release Of Cytochrome C From Mitochondria
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Intrinsic Apoptotic Signaling Pathway
Hepatocyte Apoptotic Process
Negative Regulation Of Execution Phase Of Apoptosis
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Negative Regulation Of Anoikis
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Inflammasomes
The NLRP1 inflammasome
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
Programmed Cell Death
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
Innate Immune System
Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
5 interactors:
APP
BCL2L1
NR4A1
NUDT9
PNRC2
79 interactors:
ACTB
AKT1
ANTXR1
APAF1
AVEN
BAD
BAG1
BAK1
BAX
BBC3
BCAP31
BCL2
BCL2L10
BCL2L11
BCL2L12
BCL2L14
BCLAF1
BECN1
BID
BIK
BLK
BMF
BNIP1
BNIP3
BNIP3L
BNIPL
CAPN1
CASP1
CASP8
CASP9
CDKN2A
CFLAR
CRYAA
CRYAB
CYCS
DOCK7
EDRF1
FBP1
FKBP8
GLOD4
HRK
IKZF3
IRS1
IRS2
LARP1
MAPK8
MCL1
METTL23
MOAP1
MTOR
NLRP1
PARK7
PDIA4
PLD3
PMAIP1
PPHLN1
PPP1CA
PSEN1
PSEN2
PTN
RAD9A
RAF1
RBM5
RTN1
RTN4
SIVA1
SNCA
SPNS1
TLE1
TMBIM6
TP53
TP53BP2
TPT1
UBR1
UHRF2
VDAC1
ZFYVE1
ZHX1
ZNF219
Entrez ID
51031
598
HPRD ID
12678
02497
Ensembl ID
ENSG00000167699
ENSG00000171552
Uniprot IDs
Q9HC38
Q07817
Q5TE63
PDB IDs
3ZI1
1BXL
1G5J
1LXL
1MAZ
1R2D
1R2E
1R2G
1R2H
1R2I
1YSG
1YSI
1YSN
2B48
2LP8
2LPC
2M03
2M04
2O1Y
2O2M
2O2N
2P1L
2PON
2YJ1
2YQ6
2YQ7
2YXJ
3CVA
3FDL
3FDM
3INQ
3IO8
3PL7
3QKD
3R85
3SP7
3SPF
3ZK6
3ZLN
3ZLO
3ZLR
4A1U
4A1W
4AQ3
4EHR
4HNJ
4IEH
Enriched GO Terms of Interacting Partners
?
Intracellular Receptor Signaling Pathway
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Neuron Apoptotic Process
Neuron Death
ADP Catabolic Process
Apoptotic Process In Bone Marrow
Innate Immune Response
IDP Catabolic Process
Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Synaptic Growth At Neuromuscular Junction
Collateral Sprouting In Absence Of Injury
Apoptotic Process
Programmed Cell Death
Suppression By Virus Of Host Apoptotic Process
Cell Death
Death
Collateral Sprouting
Axon Midline Choice Point Recognition
Purine Ribonucleoside Diphosphate Catabolic Process
Purine Nucleoside Monophosphate Catabolic Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Nucleobase-containing Small Molecule Catabolic Process
Negative Regulation Of Endopeptidase Activity
Negative Regulation Of Peptidase Activity
Axon Choice Point Recognition
Response To Cycloheximide
Cellular Process Regulating Host Cell Cycle In Response To Virus
Ribonucleoside Diphosphate Catabolic Process
Immune Response
Nucleoside Diphosphate Catabolic Process
Defense Response
Negative Regulation Of Execution Phase Of Apoptosis
Neuron Remodeling
Negative Regulation Of Proteolysis
Negative Regulation Of Protein Processing
Purine Ribonucleoside Catabolic Process
Regulation Of Endopeptidase Activity
Cellular Response To Virus
Negative Regulation Of Hydrolase Activity
Regulation Of Protein Processing
ADP Metabolic Process
Modulation By Virus Of Host Process
Regulation Of Peptidase Activity
Regulation Of Mitotic Cell Cycle
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Endothelial Cell Chemotaxis
Negative Regulation Of Anoikis
Response To Radiation
Aromatic Compound Catabolic Process
Cellular Response To Gamma Radiation
Apoptotic Process
Programmed Cell Death
Regulation Of Apoptotic Process
Cell Death
Death
Regulation Of Cell Death
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Positive Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrion Organization
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Mitochondrion Organization
Regulation Of Cysteine-type Endopeptidase Activity
Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Apoptotic Mitochondrial Changes
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Signal Transduction
Positive Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Endopeptidase Activity
Zymogen Activation
Positive Regulation Of Peptidase Activity
Regulation Of Endopeptidase Activity
Negative Regulation Of Programmed Cell Death
Regulation Of Signaling
Regulation Of Signal Transduction
Regulation Of Peptidase Activity
Negative Regulation Of Cell Death
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Intracellular Signal Transduction
Negative Regulation Of Apoptotic Process
Protein Processing
Positive Regulation Of Proteolysis
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Mitochondrial Membrane Permeability
Regulation Of Membrane Permeability
Regulation Of Proteolysis
Mitochondrial Membrane Organization
Positive Regulation Of Organelle Organization
Positive Regulation Of Protein Oligomerization
Regulation Of Cellular Process
Regulation Of Intracellular Transport
Mitochondrion Organization
Tagcloud
?
aacr
antiapoptotic
antiestrogens
aromatase
competitive
deprivation
drives
escaped
estrogen
eventually
fulvestrant
hcc1428
junb
kinome
letrozole
lted
mcf7
ovariectomized
parental
pharmacologic
plk1
polo
potently
recur
res
rnai
top
volasertib
xl
Tagcloud (Difference)
?
aacr
antiapoptotic
antiestrogens
aromatase
competitive
deprivation
drives
escaped
estrogen
eventually
fulvestrant
hcc1428
junb
kinome
letrozole
lted
mcf7
ovariectomized
parental
pharmacologic
plk1
polo
potently
recur
res
rnai
top
volasertib
xl
Tagcloud (Intersection)
?