GLOD4 and NR4A1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GLOD4	NR4A1
Gene Name		glyoxalase domain containing 4	nuclear receptor subfamily 4, group A, member 1
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Gene Ontology Annotations	Cellular Component	Mitochondrion Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function		DNA Binding Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process		Positive Regulation Of Endothelial Cell Proliferation Cell Migration Involved In Sprouting Angiogenesis Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Gene Expression Intracellular Receptor Signaling Pathway Endothelial Cell Chemotaxis Cellular Response To Vascular Endothelial Growth Factor Stimulus Fc-epsilon Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Innate Immune Response Positive Regulation Of Transcription From RNA Polymerase II Promoter Neurotrophin TRK Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling
Pathways			Signaling by the B Cell Receptor (BCR) Signaling by FGFR in disease PIP3 activates AKT signaling Nuclear Receptor transcription pathway Signaling by EGFRvIII in Cancer Signaling by SCF-KIT DAP12 signaling Downstream signaling events of B Cell Receptor (BCR) PI3K/AKT activation Generic Transcription Pathway PI-3K cascade PI3K events in ERBB2 signaling Downstream signaling of activated FGFR Innate Immune System Signaling by PDGF DAP12 interactions Signalling by NGF GAB1 signalosome Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by ERBB4 Constitutive PI3K/AKT Signaling in Cancer Role of LAT2/NTAL/LAB on calcium mobilization PI3K events in ERBB4 signaling Signaling by FGFR Signaling by ERBB2 Signaling by EGFR AKT phosphorylates targets in the nucleus Downstream signal transduction Fc epsilon receptor (FCERI) signaling Signaling by EGFR in Cancer PI3K/AKT Signaling in Cancer Adaptive Immune System
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		5 interactors: APP BCL2L1 NR4A1 NUDT9 PNRC2	83 interactors: ABCA5 ABCB11 ABCC13 ABCC6 ABCG8 AKT1 ANKIB1 ARHGEF10L ARHGEF5 ATXN1 BBS10 BCL2 BCL2A1 BCL2L10 CD2AP CDKN2D CHD1L CHD3 CHEK2 CPT1A CUTA DIABLO EP300 FAF1 FXYD3 GADD45GIP1 GK GLOD4 GLUD1 HADHA HES1 HIF1A HNRNPA2B1 HSP90AB1 KAT2B KRTAP10-1 KRTAP10-5 LONRF1 LSS MAP3K1 MAPK1 MAPK8 MED1 MED31 NACAD NCOA1 NCOA2 NCOA3 NCOR2 NFKB1 NR3C1 PGBD1 PML POLA2 PPARG PPBP PPM1A PRDX4 PRDX6 RBL1 ROBO2 RPL7 RPS6KA1 RPS6KA3 RPS6KA5 RPS6KA6 RTN4 RXRG SERPINA4 SERPING1 SMAD3 SOCS4 STAT3 SUGT1 TCF4 TP53 TRIM28 TUBB4A VASP VHL YWHAZ ZNF331 ZNF579
Entrez ID		51031	3164
HPRD ID		12678	00744
Ensembl ID		ENSG00000167699	ENSG00000123358
Uniprot IDs		Q9HC38	F5GXF0 P22736
PDB IDs		3ZI1	2QW4 3V3E 3V3Q
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Neuron Apoptotic Process Neuron Death ADP Catabolic Process Apoptotic Process In Bone Marrow Innate Immune Response IDP Catabolic Process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Apoptotic Process Programmed Cell Death Suppression By Virus Of Host Apoptotic Process Cell Death Death Collateral Sprouting Axon Midline Choice Point Recognition Purine Ribonucleoside Diphosphate Catabolic Process Purine Nucleoside Monophosphate Catabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Nucleobase-containing Small Molecule Catabolic Process Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Axon Choice Point Recognition Response To Cycloheximide Cellular Process Regulating Host Cell Cycle In Response To Virus Ribonucleoside Diphosphate Catabolic Process Immune Response Nucleoside Diphosphate Catabolic Process Defense Response Negative Regulation Of Execution Phase Of Apoptosis Neuron Remodeling Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Purine Ribonucleoside Catabolic Process Regulation Of Endopeptidase Activity Cellular Response To Virus Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing ADP Metabolic Process Modulation By Virus Of Host Process Regulation Of Peptidase Activity Regulation Of Mitotic Cell Cycle Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Endothelial Cell Chemotaxis Negative Regulation Of Anoikis Response To Radiation Aromatic Compound Catabolic Process Cellular Response To Gamma Radiation	Positive Regulation Of Transcription, DNA-templated Cellular Response To Organic Substance Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Cell Death Death Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Intrinsic Apoptotic Signaling Pathway Cellular Response To Stress Response To Stimulus Intracellular Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus DNA-templated Transcription, Initiation Response To Growth Factor Regulation Of Cell Death Signal Transduction Regulation Of Apoptotic Process Regulation Of Signaling Signaling Cellular Response To Stimulus Regulation Of Signal Transduction Cell Communication Apoptotic Signaling Pathway Response To Stress RNA Biosynthetic Process Regulation Of Intracellular Transport Epithelium Development Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Intracellular Signal Transduction Regulation Of Innate Immune Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Placenta Development Reproductive Structure Development Regulation Of Metabolic Process Reproductive System Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Toll-like Receptor TLR6:TLR2 Signaling Pathway
Tagcloud ?			1alpha adenine afterwards ant1 apoptotic associate associates autophagy bcl convert description hypoxic inner latest mim mom ngfib nur77 orphan outer proteasomal stabilization summarizes tr3 translocase translocated translocates translocon trapgamma
Tagcloud (Difference) ?			1alpha adenine afterwards ant1 apoptotic associate associates autophagy bcl convert description hypoxic inner latest mim mom ngfib nur77 orphan outer proteasomal stabilization summarizes tr3 translocase translocated translocates translocon trapgamma
Tagcloud (Intersection) ?