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KRTAP4-2 and AQP1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KRTAP4-2
AQP1
Gene Name
keratin associated protein 4-2
aquaporin 1 (Colton blood group)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Keratin Filament
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Axon Terminus
Apical Part Of Cell
Extracellular Vesicular Exosome
Molecular Function
Intracellular CGMP Activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Glycerol Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Ephrin Receptor Binding
Biological Process
Renal Water Homeostasis
Glomerular Filtration
Renal Water Transport
CGMP Biosynthetic Process
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Cellular Water Homeostasis
Positive Regulation Of Lamellipodium Assembly
Positive Regulation Of Epithelial Cell Migration
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Sensory Perception Of Pain
Cellular Homeostasis
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Secretory Granule Organization
Cellular Response To Stress
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Wound Healing
Odontogenesis
Response To Drug
Hyperosmotic Salinity Response
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Estrogen
Lipid Digestion
Small Molecule Metabolic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Camera-type Eye Morphogenesis
Multicellular Organismal Water Homeostasis
Corticotropin Secretion
Transmembrane Transport
Renal Water Absorption
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Metanephric Glomerulus Vasculature Development
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Cation Transmembrane Transport
Pathways
O2/CO2 exchange in erythrocytes
Erythrocytes take up carbon dioxide and release oxygen
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Erythrocytes take up oxygen and release carbon dioxide
Aquaporin-mediated transport
Drugs
Acetazolamide
Diseases
GWAS
Nephrolithiasis (
22396660
)
Protein-Protein Interactions
72 interactors:
ADAMTSL4
ALDH3B1
AMOTL2
AQP1
ATG9A
BYSL
C19orf66
CHIC2
CHRD
CRCT1
CREB5
DLGAP2
DOCK2
FAM74A4
GLRX3
GNMT
HOXA1
HPCAL1
HSD3B7
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP26-1
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LASP1
LCE1B
LCE2A
LCE3C
LCE3E
LCE4A
LNX1
MEOX2
NLK
NOTCH2NL
NR1D2
NUFIP2
OTX1
PDE9A
PGLS
PIN1
PLSCR1
POM121L8P
PRKAB2
PRKAG1
PSMA6
PVRL3
RASSF5
RGS20
SLC23A1
SLC25A10
SPATA24
SPATA3
SPRY1
TCEANC
TINAGL1
TRIM42
TXNDC5
TYRO3
WDYHV1
ZBTB24
ZNF124
ZNF20
ZNF417
ZNF559
ZNF581
42 interactors:
ADAMTSL4
CCDC136
CCDC36
CCDC57
CCDC85B
CEP44
CRTAC1
CSRNP1
EFEMP2
EPHB2
FOS
FSD2
IKZF2
IKZF3
KCTD17
KCTD9
KIAA1958
KRT31
KRT33B
KRT40
KRTAP10-3
KRTAP10-7
KRTAP4-12
KRTAP4-2
KRTAP9-2
MDFI
MID2
MTUS2
NBPF22P
NOTCH2NL
PICK1
RGS17
RGS20
RIMBP3
SIAH1
SPRY2
TCF4
TNK2
TRAF1
TRAF2
TRIM23
TRIP6
Entrez ID
85291
358
HPRD ID
13944
00140
Ensembl ID
ENSG00000244537
ENSG00000240583
Uniprot IDs
Q9BYR5
B4DPF5
B4E3E3
P29972
PDB IDs
1FQY
1H6I
1IH5
Enriched GO Terms of Interacting Partners
?
Keratinization
Keratinocyte Differentiation
Epidermal Cell Differentiation
Epidermis Development
Transcription, DNA-templated
Epithelium Development
Skin Development
RNA Biosynthetic Process
Organ Development
Tissue Development
Transepithelial Transport
Cellular Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Biosynthetic Process
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Multicellular Organismal Development
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Apoptotic Cell Clearance
BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Abducens Nerve Formation
Maintenance Of Symbiont-containing Vacuole By Host
Transepithelial Water Transport
Optokinetic Behavior
Transepithelial L-ascorbic Acid Transport
Organic Anion Transport
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Signaling
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
Regulation Of Binding
Developmental Process
Regulation Of Gene Expression
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Dendritic Spine Organization
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Signal Transduction
Axonal Fasciculation
Embryonic Organ Morphogenesis
Regulation Of Signal Transduction
Signal Transduction
Regulation Of Protein Binding
Cell Differentiation
Regulation Of Cellular Process
Face Morphogenesis
Neuron Recognition
Regulation Of Apoptotic Process
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Head Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Signaling
Regulation Of Cell Death
Positive Regulation Of Cellular Metabolic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway
Cell Communication
Negative Regulation Of Signaling
Face Development
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Nucleocytoplasmic Transport
Cellular Response To Extracellular Stimulus
Embryonic Organ Development
I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Fat Cell Differentiation
Body Morphogenesis
DNA Methylation
TRIF-dependent Toll-like Receptor Signaling Pathway
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Regulation Of Intracellular Signal Transduction
Termination Of G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Protein Binding
MyD88-independent Toll-like Receptor Signaling Pathway
Termination Of Signal Transduction
Toll-like Receptor 3 Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Tagcloud
?
2cl
absorption
acclimation
bumetanide
circuit
cl
cotransporter
eel
exchanger
gn
governed
guanylin
hco3
intestine
isc
mi
ncc
nccbeta
nkcc
nkcc2beta
nullified
player
remainder
seawater
slc26a6
teleost
transporters
versa
vice
Tagcloud (Difference)
?
2cl
absorption
acclimation
bumetanide
circuit
cl
cotransporter
eel
exchanger
gn
governed
guanylin
hco3
intestine
isc
mi
ncc
nccbeta
nkcc
nkcc2beta
nullified
player
remainder
seawater
slc26a6
teleost
transporters
versa
vice
Tagcloud (Intersection)
?