KRTAP4-2 and DLGAP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KRTAP4-2	DLGAP2
Description		keratin associated protein 4-2	DLG associated protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Neurofilament Plasma Membrane Postsynaptic Density Membrane Synapse Glutamatergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	Hair Cycle	Neuron-neuron Synaptic Transmission Signaling Modulation Of Chemical Synaptic Transmission
Pathways		Keratinization
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Daytime nap ( 33568662) End-stage renal disease ( 29885931) Eye morphology ( 29921221) Femur bone mineral density x serum urate levels interaction ( 34046847) Lung cancer ( 28604730) Menarche (age at onset) ( 23599027) Neuritic plaque ( 31497858) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive astigmatism ( 30306274) Stroke ( 32693751) Tau burden ( 33426524) Triglycerides ( 24886709) White matter microstructure in first episode schizophrenia (right posterior cingulate cortex) ( 28924203)
Interacting Genes		130 interacting genes: ADAMTSL4 ALDH3B1 AMOTL2 ANKS1A AQP1 ATG9A AVPI1 AXIN1 BAG4 BYSL CATSPER1 CCER1 CELF5 CHIC2 CHRD CRCT1 CREB5 CRY2 CYP21A2 CYSRT1 DLGAP2 DOCK2 FAM74A4 GLRX3 GNMT GUCD1 HOXA1 HOXB9 HPCAL1 HSD3B7 ITGB4 KPRP KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP26-1 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LASP1 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 MAFB MEOX2 NBPF19 NECTIN3 NLK NOTCH2NLA NR1D2 NR4A3 NTAQ1 NUFIP2 OTX1 OXER1 PDE9A PGLS PHLDA1 PIN1 PLSCR1 PLSCR4 POM121L8P POU4F2 PRKAB2 PRKAG1 PSMA6 RASSF5 RGS20 SDC3 SHFL SLC23A1 SLC25A10 SMCP SPATA24 SPATA3 SPRY1 TCEANC TINAGL1 TRIM42 TXNDC5 TYRO3 VASN VGLL3 YY1 ZBTB24 ZNF124 ZNF20 ZNF417 ZNF559 ZNF581 ZNF688	18 interacting genes: ABI2 ADRB1 CYSRT1 DGCR6 DLG2 DLG4 DLGAP1 GRK5 KRT40 KRTAP4-2 MAGI2 NLGN4X NOS1 SHANK2 SHANK3 SORBS2 TSPOAP1 UBASH3B
Entrez ID		85291	9228
HPRD ID		13944	09258
Ensembl ID		ENSG00000244537	ENSG00000198010
Uniprot IDs		A0AAG2UW37 Q9BYR5	A0A1B0GTN4
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Protein Binding Hair Cycle Identical Protein Binding Abducens Nerve Formation	Postsynaptic Density Vocalization Behavior Ionotropic Glutamate Receptor Binding Receptor Clustering Synapse Social Behavior Dendritic Spine Scaffold Protein Binding Beta-1 Adrenergic Receptor Binding Synaptic Receptor Adaptor Activity AMPA Glutamate Receptor Clustering Modulation Of Chemical Synaptic Transmission Modulation Of Excitatory Postsynaptic Potential Learning Neuron Projection Cell Projection Synaptic Signaling Neuron Spine Photoreceptor Inner Segment Juxtaparanode Region Of Axon Regulation Of Membrane Potential Neurotransmitter-gated Ion Channel Clustering Cellular Response To Potassium Ion Postsynaptic Membrane Dendritic Spine Morphogenesis Kinase Binding Postsynaptic Density Membrane Learning Or Memory Calyx Of Held Response To Potassium Ion SH3 Domain Binding Cytoskeletal Anchor Activity Regulation Of System Process Regulation Of Nervous System Process Regulation Of Cell Communication Regulation Of Signaling Protein Localization To Membrane Chemical Synaptic Transmission Cognition Regulation Of The Force Of Heart Contraction Regulation Of Long-term Neuronal Synaptic Plasticity Cell-cell Signaling Trans-synaptic Signaling Signaling Excitatory Synapse Positive Regulation Of Synaptic Transmission Positive Regulation Of Excitatory Postsynaptic Potential Dendritic Spine Organization Adult Behavior Cell Communication
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