NBN and CHEK2

  • Number of citations of the paper that reports this interaction (PMID 11438675)
  • 39
  • Data Source:
  • HPRD (in vitro)

NBN

CHEK2

Gene Name nibrin checkpoint kinase 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 27 interactors: ATF2 ATM ATR BRCA1 CCNE1 CDK9 CHEK2 DCLRE1C EP300 FANCD2 H2AFX MDC1 MRE11A NCL PRKDC RAD18 RAD50 RECQL5 RNF8 SIRT1 TERF1 TLK1 TREX1 UBE2D1 UBE2N XRCC4 XRCC5 47 interactors: AATF APP ARHGAP1 ASF1A ATM ATR BRCA1 BRCA2 CDC25A CDC25C DAPK3 DBF4 E2F1 ELAVL1 ERCC6 FOXM1 KPNA2 LATS2 MDC1 MDM2 MDM4 MRC1 MSH2 MUS81 NBN NR4A1 PLK1 PLK3 POLR2L PPP2CA PPP2R2A PPP2R2B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RAD9A RCHY1 REV3L RNF8 SRPK1 STRAP TP53 TSSK1B VHL
Entrez ID 4683 11200
HPRD ID 04050 05084
Ensembl ID ENSG00000104320 ENSG00000183765
Uniprot IDs O60934 O96017
PDB IDs 1GXC 2CN5 2CN8 2W0J 2W7X 2WTC 2WTD 2WTI 2WTJ 2XBJ 2XK9 2XM8 2XM9 2YCF 2YCQ 2YCR 2YCS 2YIQ 2YIR 2YIT 3I6U 3I6W 3VA4 4A9R 4A9S 4A9T 4A9U 4BDA 4BDB 4BDC 4BDD 4BDE 4BDF 4BDG 4BDH 4BDI 4BDJ 4BDK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5yrs  atm  atr  brfr  category  cohorts  ddr  decisions  fail  gains  gleason  guided  igrt  mre11a  nibrin  pca  precision  predictor  predicts  prkdc  prostatectomy  psa  rad50  radioresistance  radiotherapy  radp  sensing  sensors  wald 
alleles  atm  brca1  brca2  brip1  cdh1  confer  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
Tagcloud (Difference) ?
5yrs  atr  brfr  category  cohorts  ddr  decisions  fail  gains  gleason  guided  igrt  mre11a  nibrin  pca  precision  predictor  predicts  prkdc  prostatectomy  psa  rad50  radioresistance  radiotherapy  radp  sensing  sensors  wald 
alleles  brca1  brca2  brip1  cdh1  confer  contributing  contributive  fashion  hereditary  influences  lifetime  offers  otherwise  palb2  penetrance  penetrant  personal  polygenic  predisposing  predisposition  quite  snp  stk11  suggestive  suspicion  unlikely  venue 
Tagcloud (Intersection) ?
atm