NBN and SIRT1

  • Number of citations of the paper that reports this interaction (PMID 17612497)
  • 75
  • Data Source:
  • BioGRID (enzymatic study)

NBN

SIRT1

Gene Name nibrin sirtuin 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 27 interactors: ATF2 ATM ATR BRCA1 CCNE1 CDK9 CHEK2 DCLRE1C EP300 FANCD2 H2AFX MDC1 MRE11A NCL PRKDC RAD18 RAD50 RECQL5 RNF8 SIRT1 TERF1 TLK1 TREX1 UBE2D1 UBE2N XRCC4 XRCC5 47 interactors: AKT1 ARNTL BCL11A BHLHE41 CDK6 CSNK2B CTTN EP300 ESRRA FOS FOXO1 FOXO3 GAPDH HES1 HEY2 HIC1 HIST1H1B HIST1H3A HNF4A IRS2 MAPK8 MAPT MYCN NBN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARGC1A PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SNW1 SREBF1 STK11 STK4 TP53 UBE2I VDR
Entrez ID 4683 23411
HPRD ID 04050 08381
Ensembl ID ENSG00000104320 ENSG00000096717
Uniprot IDs O60934 A8K128 B0QZ35 E9PC49 Q96EB6
PDB IDs 4I5I
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5yrs  atm  atr  brfr  category  cohorts  ddr  decisions  fail  gains  gleason  guided  igrt  mre11a  nibrin  pca  precision  predictor  predicts  prkdc  prostatectomy  psa  rad50  radioresistance  radiotherapy  radp  sensing  sensors  wald 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Difference) ?
5yrs  atm  atr  brfr  category  cohorts  ddr  decisions  fail  gains  gleason  guided  igrt  mre11a  nibrin  pca  precision  predictor  predicts  prkdc  prostatectomy  psa  rad50  radioresistance  radiotherapy  radp  sensing  sensors  wald 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Intersection) ?