MEST and CEP70

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MEST	CEP70
Gene Name		mesoderm specific transcript	centrosomal protein 70kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Centrosome Cytosol Nuclear Membrane
	Molecular Function	Hydrolase Activity	Protein Binding
	Biological Process	Mesoderm Development Metabolic Process Regulation Of Lipid Storage Response To Retinoic Acid	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APP BAG6 BLOC1S2 CD300C CEP70 CMTM3 CRELD2 DBN1 FEZ1 FST HGS ING5 KIFAP3 MPZL2 ZNF205 ZNF579	134 interactors: ABT1 AKAP17A ARHGEF3 ATP5O ATXN7 BARD1 BEX2 BRMS1 BYSL C11orf57 C1orf35 C7orf25 C8orf33 CARD9 CCDC85B CCDC94 CDC73 CDCA7L CEP57L1 CFAP53 CLPB COIL DAZAP2 DDX41 DDX6 DIEXF DNAJB11 EMD EMP1 ENKD1 ERCC3 FAM118B FAM124A FAM133A FAM13C FAM161A FAM214B FAM64A GATAD2B GCC1 GPATCH2L GPATCH4 GPX7 HAUS1 HMGB4 HSPD1 IK IQCE KANK2 KANSL1 KAT7 KDM1A KRT31 LAMTOR5 LENG1 LENG8 LIN37 MCM10 MEST METTL17 MFAP1 MRPL44 NIPSNAP3A NKAP NOL12 NOP2 NRIP1 NUSAP1 PAM16 PLA2G2A PPFIA1 PPIG PPP1R16B PRKRIP1 PRPF31 PSMA1 RCOR3 RPL13 SERPINH1 SETD5 SFR1 SH2D4A SLU7 SMARCE1 SNRPD2 SRGN SSX3 STK25 STMN2 SUV39H1 SUV39H2 SYT17 SYTL4 SYTL5 TAF1D TCEB3 TCEB3B TEAD4 TRIM29 TRIM42 TSGA10IP TSHZ3 TTC25 TTLL10 TXLNB UTP11L UTP14A ZBTB16 ZBTB24 ZBTB49 ZBTB8A ZCCHC10 ZFC3H1 ZGPAT ZNF136 ZNF148 ZNF169 ZNF227 ZNF239 ZNF266 ZNF302 ZNF329 ZNF366 ZNF408 ZNF410 ZNF417 ZNF426 ZNF439 ZNF490 ZNF555 ZNF572 ZNF578 ZNF587 ZSCAN12
Entrez ID		4232	80321
HPRD ID		06776	16779
Ensembl ID		ENSG00000106484	ENSG00000114107
Uniprot IDs		A4D1L9 B4DQW6 Q5EB52	B7Z2D2 Q8NHQ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Localization Axon Cargo Transport Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Calcium-dependent Cell-cell Adhesion Microtubule-based Movement Regulation Of Gene Expression Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Organelle Localization Regulation Of ERBB Signaling Pathway Synaptic Growth At Neuromuscular Junction Immune System Process Regulation Of Signaling Regulation Of Cell Proliferation Membrane Organization Collateral Sprouting In Absence Of Injury Cell Communication By Chemical Coupling Regulation Of Dendrite Development Organelle Localization Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Cell Differentiation Internal Protein Amino Acid Acetylation Collateral Sprouting Axon Midline Choice Point Recognition Protein Acetylation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Plus-end-directed Vesicle Transport Along Microtubule Regulation Of Cellular Process Axon Choice Point Recognition Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of B Cell Receptor Signaling Pathway Regulation Of Neuron Differentiation Regulation Of Signal Transduction Protein Insertion Into ER Membrane Chemotaxis Establishment Of Localization In Cell Neuron Remodeling Negative Regulation Of Activin Receptor Signaling Pathway Mitochondrial Outer Membrane Permeabilization Platelet Dense Granule Organization Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of Hair Follicle Development Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Establishment Of Vesicle Localization Negative Regulation Of Cellular Metabolic Process	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Ribonucleoprotein Complex Biogenesis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process RRNA Processing Regulation Of Cellular Process RRNA Metabolic Process Ribosomal Small Subunit Biogenesis Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification MRNA Metabolic Process Metabolic Process Ribosome Biogenesis Histone H3-K9 Dimethylation RNA Processing Chromatin Organization Histone Modification Maturation Of SSU-rRNA Chromosome Organization Cell Death Death Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Apoptotic Process
Tagcloud ?		bovid contributions die diverged domestic establishes evolutionarily father genomes igf2 imprinted imprinting know mammals mother parthenogenetic paternal peg1 placental postimplantation proceed retardation retarded ruminant ruminants sheep theories versa vice
Tagcloud (Difference) ?		bovid contributions die diverged domestic establishes evolutionarily father genomes igf2 imprinted imprinting know mammals mother parthenogenetic paternal peg1 placental postimplantation proceed retardation retarded ruminant ruminants sheep theories versa vice
Tagcloud (Intersection) ?