MEST and ING5

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MEST	ING5
Gene Name		mesoderm specific transcript	inhibitor of growth family, member 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Hydrolase Activity	Chromatin Binding Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	Mesoderm Development Metabolic Process Regulation Of Lipid Storage Response To Retinoic Acid	DNA Replication Chromatin Organization Transcription, DNA-templated Protein Acetylation Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Positive Regulation Of Apoptotic Signaling Pathway
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APP BAG6 BLOC1S2 CD300C CEP70 CMTM3 CRELD2 DBN1 FEZ1 FST HGS ING5 KIFAP3 MPZL2 ZNF205 ZNF579	34 interactors: APC APLP1 ARFIP2 BARD1 C3orf62 CCDC33 CCDC67 CDCA7L CDKN1A CEP44 EP300 FAM118B GCSH HAP1 HGS HTT ICA1 IKZF3 JADE2 KIAA1377 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 PCM1 PRMT5 SMARCE1 TADA3 TAF1D TP53 VIM
Entrez ID		4232	84289
HPRD ID		06776	16348
Ensembl ID		ENSG00000106484	ENSG00000168395
Uniprot IDs		A4D1L9 B4DQW6 Q5EB52	Q8WYH8
PDB IDs			3C6W
Enriched GO Terms of Interacting Partners?		Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Localization Axon Cargo Transport Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Calcium-dependent Cell-cell Adhesion Microtubule-based Movement Regulation Of Gene Expression Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Organelle Localization Regulation Of ERBB Signaling Pathway Synaptic Growth At Neuromuscular Junction Immune System Process Regulation Of Signaling Regulation Of Cell Proliferation Membrane Organization Collateral Sprouting In Absence Of Injury Cell Communication By Chemical Coupling Regulation Of Dendrite Development Organelle Localization Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Cell Differentiation Internal Protein Amino Acid Acetylation Collateral Sprouting Axon Midline Choice Point Recognition Protein Acetylation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Plus-end-directed Vesicle Transport Along Microtubule Regulation Of Cellular Process Axon Choice Point Recognition Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of B Cell Receptor Signaling Pathway Regulation Of Neuron Differentiation Regulation Of Signal Transduction Protein Insertion Into ER Membrane Chemotaxis Establishment Of Localization In Cell Neuron Remodeling Negative Regulation Of Activin Receptor Signaling Pathway Mitochondrial Outer Membrane Permeabilization Platelet Dense Granule Organization Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of Hair Follicle Development Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Establishment Of Vesicle Localization Negative Regulation Of Cellular Metabolic Process	Mitotic Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Chromosome Organization Cell Cycle Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Cell Cycle Regulation Of Tubulin Deacetylation Histone Acetylation Mitotic Cell Cycle Phase Transition Internal Peptidyl-lysine Acetylation Cell Cycle Phase Transition Peptidyl-lysine Acetylation Cytoplasmic Microtubule Organization Chromatin Organization Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Gene Expression Cell Cycle Arrest Histone H3 Acetylation Regulation Of Protein Deacetylation Circadian Rhythm Chromatin Modification Stress-induced Premature Senescence Histone Modification Cell Aging Apoptotic Process Negative Regulation Of Gene Expression Tissue Development Central Nervous System Development Regulation Of Mitotic Cell Cycle Negative Regulation Of Biosynthetic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Mitotic Cell Cycle Arrest Programmed Cell Death Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Intracellular Transport Regulation Of Cellular Localization Regulation Of Cell Cycle Phase Transition Cell Death Death Nervous System Development Epithelium Development Determination Of Adult Lifespan
Tagcloud ?		bovid contributions die diverged domestic establishes evolutionarily father genomes igf2 imprinted imprinting know mammals mother parthenogenetic paternal peg1 placental postimplantation proceed retardation retarded ruminant ruminants sheep theories versa vice	acetylates acetyllysine bonding bromodomain brpf1 calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally
Tagcloud (Difference) ?		bovid contributions die diverged domestic establishes evolutionarily father genomes igf2 imprinted imprinting know mammals mother parthenogenetic paternal peg1 placental postimplantation proceed retardation retarded ruminant ruminants sheep theories versa vice	acetylates acetyllysine bonding bromodomain brpf1 calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally
Tagcloud (Intersection) ?