MEST and BAG6

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MEST	BAG6
Gene Name		mesoderm specific transcript	BCL2-associated athanogene 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle BAT3 Complex
	Molecular Function	Hydrolase Activity	Protein Binding Hsp70 Protein Binding Polyubiquitin Binding Ubiquitin Protein Ligase Binding Ribosome Binding Proteasome Binding
	Biological Process	Mesoderm Development Metabolic Process Regulation Of Lipid Storage Response To Retinoic Acid	Kidney Development Immune System Process Ubiquitin-dependent Protein Catabolic Process Transport Synaptonemal Complex Assembly Spermatogenesis Brain Development Embryo Development Chromatin Modification Internal Peptidyl-lysine Acetylation Cell Differentiation Lung Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Proliferation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Negative Regulation Of Proteolysis Protein Stabilization Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS			Schizophrenia ( 23894747)
Protein-Protein Interactions		16 interactors: APP BAG6 BLOC1S2 CD300C CEP70 CMTM3 CRELD2 DBN1 FEZ1 FST HGS ING5 KIFAP3 MPZL2 ZNF205 ZNF579	102 interactors: ACVR1B AMFR ANXA7 ARPC3 ATN1 ATXN2 B2M C1QA CD93 CDK16 CDK4 CDK5 CDKN1A CHN2 CLU CSNK2B CSTF2 CTCFL CTSB CTSE CTSL CXCL8 DNAJB11 DPT EDN1 EFEMP1 EFEMP2 EP300 FAM173A FAM46A FAM9B FAS FKBP2 FZD4 GADD45A GLRA2 GSK3B HSPA13 HSPA8 ICK IGF2 IGFBP5 IKBKAP IMMT IQCG KLHL12 LBP LPPR3 MAPK6 MAVS MEST MYDGF NBL1 NCR3 NDUFA6 NDUFB11 NOMO1 NPY NR1H2 PELP1 PIN1 PLA2G2A PLK1 POLR2J PPAP2C PRMT2 PRNP PRPF40A PTH PTN PTPN12 RAB8A RAC1 RCC1 RCN2 REG1B RNF126 S100A4 SDC2 SEC61A1 SEC61B SERPING1 SERPINH1 SETDB1 SGTA SMN1 SPP1 SRGN STX5 TAC1 TDGF1 TFCP2 TK1 TOMM20 TP63 TTR UBL4A UBL7 UBQLN4 VAMP2 XRN1 ZFYVE9
Entrez ID		4232	7917
HPRD ID		06776	00808
Ensembl ID		ENSG00000106484	ENSG00000204463
Uniprot IDs		A4D1L9 B4DQW6 Q5EB52	P46379
PDB IDs			1WX9 4DWF 4EEW
Enriched GO Terms of Interacting Partners?		Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Localization Axon Cargo Transport Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Calcium-dependent Cell-cell Adhesion Microtubule-based Movement Regulation Of Gene Expression Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Organelle Localization Regulation Of ERBB Signaling Pathway Synaptic Growth At Neuromuscular Junction Immune System Process Regulation Of Signaling Regulation Of Cell Proliferation Membrane Organization Collateral Sprouting In Absence Of Injury Cell Communication By Chemical Coupling Regulation Of Dendrite Development Organelle Localization Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Cell Differentiation Internal Protein Amino Acid Acetylation Collateral Sprouting Axon Midline Choice Point Recognition Protein Acetylation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Plus-end-directed Vesicle Transport Along Microtubule Regulation Of Cellular Process Axon Choice Point Recognition Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of B Cell Receptor Signaling Pathway Regulation Of Neuron Differentiation Regulation Of Signal Transduction Protein Insertion Into ER Membrane Chemotaxis Establishment Of Localization In Cell Neuron Remodeling Negative Regulation Of Activin Receptor Signaling Pathway Mitochondrial Outer Membrane Permeabilization Platelet Dense Granule Organization Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of Hair Follicle Development Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Establishment Of Vesicle Localization Negative Regulation Of Cellular Metabolic Process	Response To Organic Substance Response To Stress Response To Stimulus Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Signaling Cell Communication Positive Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Protein Phosphorylation Immune Response Regulation Of Immune System Process Regulation Of Protein Phosphorylation Cellular Response To Stimulus Defense Response Regulation Of Signaling Anatomical Structure Development Positive Regulation Of Cellular Protein Metabolic Process Innate Immune Response Regulation Of Cell Cycle Response To External Stimulus Signal Transduction Developmental Process Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Regulation Of Cellular Component Organization Positive Regulation Of Immune System Process Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Cell Development System Development Regulation Of Phosphorylation Regulation Of Signal Transduction Response To Hormone Immune System Process Response To Lipid Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Protein Metabolic Process Regulation Of Cellular Process Cellular Process Regulation Of Catalytic Activity Response To Abiotic Stimulus Positive Regulation Of Metabolic Process Regulation Of Cell Motility Apoptotic Signaling Pathway Multicellular Organismal Development Positive Regulation Of Signal Transduction
Tagcloud ?		bovid contributions die diverged domestic establishes evolutionarily father genomes igf2 imprinted imprinting know mammals mother parthenogenetic paternal peg1 placental postimplantation proceed retardation retarded ruminant ruminants sheep theories versa vice	biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Difference) ?		bovid contributions die diverged domestic establishes evolutionarily father genomes igf2 imprinted imprinting know mammals mother parthenogenetic paternal peg1 placental postimplantation proceed retardation retarded ruminant ruminants sheep theories versa vice	biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Intersection) ?