LASP1 and THAP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LASP1	THAP1
Gene Name		LIM and SH3 protein 1	THAP domain containing, apoptosis associated protein 1
Image
Gene Ontology Annotations	Cellular Component	Focal Adhesion Cortical Actin Cytoskeleton Extracellular Vesicular Exosome	Nucleus PML Body
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding Zinc Ion Binding Ion Transmembrane Transporter Activity Actin Filament Binding	Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Ion Transport Positive Regulation Of Signal Transduction Ion Transmembrane Transport	Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: ACD ACTA1 ACTB ACTC1 ARHGEF15 ATXN1 CDK7 DAZAP2 FHL3 FXR2 GOLGA2 KRTAP4-2 LZTS2 MDFI PLSCR1 POT1 PRKAR2B PRKG1 PRKG2 PSMA3 REL RHOXF2 SEPT3 SPRY2 TCF4 TERF1 THAP1 TINF2 TRIM27 TRIP13 ZBTB9 ZC2HC1A ZYX	58 interactors: ACOT7 AKAP17A AKAP9 AP2B1 ARL6IP4 BAG5 BMS1P5 BYSL C11orf57 C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 FAM124A FAM133A FXR2 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WDYHV1 YES1 ZCCHC10 ZNF385C ZNF408
Entrez ID		3927	55145
HPRD ID		04229	15496
Ensembl ID		ENSG00000002834	ENSG00000131931
Uniprot IDs		B4DGQ0 B4DIC4 Q14847	Q9NVV9
PDB IDs		3I35	2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Assembly Organelle Organization Cell Cycle Negative Regulation Of DNA Replication Negative Regulation Of Cellular Metabolic Process Regulation Of Telomerase Activity Cellular Component Assembly Telomere Maintenance Negative Regulation Of Transferase Activity Regulation Of Catalytic Activity Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomere Lengthening Regulation Of Nitrogen Compound Metabolic Process Regulation Of DNA Replication Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Cellular Metabolic Process Regulation Of DNA Biosynthetic Process Regulation Of Cellular Process Cell Cycle Process Skeletal Muscle Thin Filament Assembly Positive Regulation Of Telomerase Activity Mitotic Cell Cycle Regulation Of Protein Metabolic Process Skeletal Myofibril Assembly Negative Regulation Of Cellular Protein Metabolic Process Cytoskeleton Organization Positive Regulation Of Transferase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Actin Cytoskeleton Organization Negative Regulation Of Protein Metabolic Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Metabolic Process Response To Stress Regulation Of Chromosome Organization Actin Filament-based Process Positive Regulation Of Organelle Organization Blood Coagulation Mitotic Cell Cycle Process Hemostasis Chromosome Organization	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Regulation Of Gene Expression RNA Splicing Macromolecule Biosynthetic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Processing MRNA Processing Cellular Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Metabolic Process Positive Regulation Of Gene Expression Metabolic Process Negative Regulation Of Glucose Import Negative Regulation Of Cellular Metabolic Process Cellular Process Negative Regulation Of Gene Expression, Epigenetic Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Glucose Transport Negative Regulation Of Gene Expression Segment Specification Positive Regulation Of Metabolic Process Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Glucose Transport Regulation Of RNA Splicing Regulation Of Protein Metabolic Process MRNA Transport Fatty Acid Biosynthetic Process Positive Regulation Of RNA Splicing Palmitic Acid Biosynthetic Process Negative Regulation Of Mitochondrial DNA Replication Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Maintenance Of ER Location Negative Regulation Of Glucosylceramide Biosynthetic Process
Tagcloud ?		already axis colonization correlates cytoskeletal deaths distant effectors epithelia hnscc inhibits integrated metastasis metastatic mir mirna multilayered neck nuak1 organs postextravasation prometastatic reactivation reconstitution remodeling sparc suppressing triggers underpins	assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper
Tagcloud (Difference) ?		already axis colonization correlates cytoskeletal deaths distant effectors epithelia hnscc inhibits integrated metastasis metastatic mir mirna multilayered neck nuak1 organs postextravasation prometastatic reactivation reconstitution remodeling sparc suppressing triggers underpins	assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper
Tagcloud (Intersection) ?