LASP1 and TRIP13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		LASP1	TRIP13
Description		LIM and SH3 protein 1	thyroid hormone receptor interactor 13
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Focal Adhesion Cell Cortex Cortical Actin Cytoskeleton Postsynapse	Male Germ Cell Nucleus Nucleus Chromosome
	Molecular Function	Actin Binding Protein Binding Monoatomic Ion Transmembrane Transporter Activity Cadherin Binding Metal Ion Binding Actin Filament Binding	Nucleotide Binding Transcription Coregulator Activity Protein Binding ATP Binding ATP Hydrolysis Activity Identical Protein Binding
	Biological Process	Monoatomic Ion Transport Monoatomic Ion Transmembrane Transport	Oocyte Maturation Double-strand Break Repair Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Signaling Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Cell Differentiation Oogenesis Meiotic Cell Cycle Meiotic Recombination Checkpoint Signaling
Pathways
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)	Pancreatic cancer ( 25086665)
Interacting Genes		121 interacting genes: ACD ACTA1 ACTB ACTC1 ACTMAP ANKS1A ARHGEF15 ARHGEF16 ARID5A ATXN1 BAG4 BAHD1 BHLHE40 C14orf119 CAMK2A CATSPER1 CDK7 CEBPA CERCAM CHERP COPS5 CRK CRYBA1 CRYBA2 CSTF2T CTNNA3 CYSRT1 DAZAP2 DMRT3 DNMT1 DOK6 DRC4 DTX2 EHMT2 EVX2 FAM168A FAM168B FBXO17 FHL3 FOXH1 FXR2 GCM2 GOLGA2 GUCD1 HGS HNRNPF HOXA1 INTS11 KRTAP10-8 KRTAP12-4 KRTAP19-3 KRTAP19-4 KRTAP19-6 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP6-2 LENG8 LMO4 LZTS2 MDFI MED25 MGAT5B MKRN3 NOXA1 NUTF2 OTX1 OXER1 PITX1 PLSCR1 POLD1 POT1 POU1F1 PRKAR2B PRKG1 PRKG2 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 PSMA3 QRICH1 RBFOX1 RBPMS RBPMS2 REL RHOXF2 RNF38 SAXO4 SEPTIN3 SPAG8 SPRY2 STAT3 TCF4 TEKT3 TEKT4 TEKT5 TERF1 TFG THAP1 TINF2 TLX3 TNS2 TRIM27 TRIP13 UFSP1 UHRF1 VAC14 VEZF1 VGLL3 VPS37C WWOX YES1 YTHDF1 ZBTB9 ZC2HC1A ZC3H10 ZYX	113 interacting genes: ACTMAP ADAM15 AMDHD2 ANKRD10 ARL11 ARSA ASB13 BKGD BUB1B C4orf33 CARD14 CD99 CDC20 CDIN1 CEP170B CFP CLIP4 COMT CRMP1 CRYBA2 CYB5R2 DCTN3 DDAH2 DIP2A DPYSL4 DTX2 EEF2KMT FBLN5 FBXO8 FILNC1 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 IGFN1 IL2RB INCA1 INTS11 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MBLAC1 MEAK7 METTL15 MGAT5B MORN3 MPPED2 MVP MYEOV NIF3L1 NME4 NTAQ1 PARP11 PAX9 PBLD PCMTD2 PCSK5 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 POLR2L PPP2CA PRKAA2 PRKN PRR13 PSMB8 QARS1 RBPMS RHOXF2 RNF4 SCP2 SDCBP SEC24A SELENBP1 SEMA3B SEMA4G SHARPIN SIGLEC5 SMUG1 SPMIP9 SPRYD7 SSC4D STAMBP STAMBPL1 SUMO2 TENT5B THRB TINAGL1 TNRC6A TPT1 UBE2I VDR VENTX ZMYM5 ZNF34 ZNF655
Entrez ID		3927	9319
HPRD ID		04229	05145
Ensembl ID		ENSG00000002834	ENSG00000071539
Uniprot IDs		B4DIC4 Q14847	Q15645
PDB IDs		3I35	5VQ9 5VQA 5WC2 6F0X 6LK0 7L9P
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Shelterin Complex Regulation Of Nucleobase-containing Compound Metabolic Process Intermediate Filament Nuclear Telomere Cap Complex Axonemal A Tubule Inner Sheath Positive Regulation Of Nucleobase-containing Compound Metabolic Process Telomere Capping Telomere Assembly Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Sperm Flagellum Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Flagellated Sperm Motility Sperm Motility Cilium-dependent Cell Motility Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cilium Movement Involved In Cell Motility Telomeric DNA Binding Neuron Fate Specification Regulation Of Macromolecule Metabolic Process CGMP-dependent Protein Kinase Activity Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Cytoplasmic Stress Granule DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of DNA Biosynthetic Process Chromatin Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Nucleus DNA Binding Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Negative Regulation Of Telomere Maintenance Regulation Of Metabolic Process Cilium Movement Negative Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Via Telomerase Transcription Regulator Complex Mesenchyme Migration	Protein Binding Mitotic Checkpoint Complex Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Protein K6-linked Ubiquitination Intermediate Filament
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?