IL4R and PTPN6

  • Number of citations of the paper that reports this interaction (PMID 11714803)
  • 11
  • Data Source:
  • HPRD (in vivo, in vitro)

IL4R

PTPN6

Gene Name interleukin 4 receptor protein tyrosine phosphatase, non-receptor type 6
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 22 interactors: ARIH2 CD40 DOK2 FES GNB2L1 HGS IL13 IL13RA1 IL2RG IL4 INPP5D IRS1 IRS2 JAK1 JAK2 JAK3 PRKCZ PTPN11 PTPN6 SHC1 SOCS5 STAT6 98 interactors: ABL1 ACTN1 ACTN4 BCR BLNK BTLA C6orf25 CAV1 CBL CD22 CD247 CD300LF CD33 CD5 CD72 CD79A CD79B CEACAM1 CLEC4A CSF2RB CTNNB1 CTNND1 CUZD1 CXCR4 DOK1 EGFR EPOR ESR1 FAS FCGR2B FCRL3 FHL3 FLT3 GAB2 GHR GRB2 HOXA10 IFNAR1 IL2RB IL4R IL6ST INSR IRS2 IRS4 JAK1 JAK2 JAK3 KDR KHDRBS1 KIR2DL3 KIR2DL5A KIT KLRAP1 KLRB1 KLRC1 LAIR1 LCK LCP2 LIFR LILRB2 LILRB4 LYN MS4A2 MYH9 NOS1 PAG1 PECAM1 PIK3R1 PILRA PILRB PRKCA PRKCD PTK2B PTPN11 PTPRC ROS1 SHC1 SIGLEC10 SIGLEC11 SIGLEC12 SIRPA SLAMF6 SOS1 SPATA2 SRC SSTR2 STAT5B STAT6 SYK TFG TLR10 TMEM62 TNFRSF1A TRAF6 TREML1 TYK2 VAV1 ZAP70
Entrez ID 3566 5777
HPRD ID 00990 01475
Ensembl ID ENSG00000077238 ENSG00000111679
Uniprot IDs B2RBY1 B4E076 P24394 P29350 Q53XS4
PDB IDs 1IAR 1IRS 1ITE 3BPL 3BPN 3BPO 1FPR 1GWZ 1X6C 2B3O 2RMX 2YU7 3PS5 4GRY 4GRZ 4GS0 4HJP 4HJQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
4ps  ba  compatible  coupling  depend  equimolar  exclusive  f3  heterodimerization  i4r  il2  il2r  il7  il9  immunoblotting  jak1  jak3  manifest  mutational  phosphotyrosine  preferential  premyeloid  share  stably  subordinate  tf  tyk2  vigorous 
a2  ag  cd45  chimera  chimeras  chimeric  coupling  diminished  enzymatic  fails  hcp  hemopoietic  initiated  inositol  j45  jurkat  ligation  lymphoid  phosphatase  phospholipase  phosphotyrosine  ptp1c  rescue  shp  shptp  surprisingly  tcr  transduction  unlike 
Tagcloud (Difference) ?
4ps  ba  compatible  depend  equimolar  exclusive  f3  heterodimerization  i4r  il2  il2r  il7  il9  immunoblotting  jak1  jak3  manifest  mutational  preferential  premyeloid  share  stably  subordinate  tf  tyk2  vigorous 
a2  ag  cd45  chimera  chimeras  chimeric  diminished  enzymatic  fails  hcp  hemopoietic  initiated  inositol  j45  jurkat  ligation  lymphoid  phosphatase  phospholipase  ptp1c  rescue  shp  shptp  surprisingly  tcr  transduction  unlike 
Tagcloud (Intersection) ?
coupling  phosphotyrosine