NEDD4L and SGK1

  • Number of citations of the paper that reports this interaction (PMID 11742982)
  • 123
  • Data Source:
  • BioGRID (enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology)
  • HPRD (in vitro)

NEDD4L

SGK1

Gene Name neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase serum/glucocorticoid regulated kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Insomnia (caffeine-induced) ( 22754043)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 22001757)
  • Response to amphetamines ( 22952603)
  • Body mass index (interaction) ( 23192594)
  • Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Protein-Protein Interactions 126 interactors: AATF ABL1 ABL2 ACVR1B ACY3 ADAP2 AICDA AKT3 APEX2 ARHGDIA AURKC BBX BMPR1A BRAF C7orf50 CACNB1 CAMK1D CDC34 CDK3 CDK5 CLIC2 CUEDC1 CYBRD1 CYP26B1 DAPK3 DAZAP2 DDX54 DECR2 DMTN DYRK3 EFEMP2 FGF12 FKBP3 GORAB H1F0 HAX1 HGS IFRD2 IKBKB KCNAB1 KCNAB2 KCNAB3 KCNB1 KIF3B KIFC3 LAPTM5 MAGEB1 MAP2 MAP3K2 MAP3K3 MAP3K5 MAPKAPK3 MARK2 MERTK MINK1 MOB3A MRPL19 NDFIP2 NHP2 NR3C1 NSRP1 NTRK1 NUDT16L1 PBX1 PRKX PRR16 PRRG1 PSMD4 RANBP10 RASL10B RASL11B RNF11 RNF7 ROBO3 RPL30 RPS6KB2 SCAMP3 SCD SCN5A SCNN1A SCNN1B SCNN1G SENP2 SERPINF1 SGK1 SGK2 SIVA1 SLC7A7 SMAD2 SMAD3 SMAD7 SNCA SPAG8 SRMS STAC STK40 TAF1B TARBP2 TBC1D7 TCEAL2 TGFB1I1 TMA16 TMEM55A TRIM41 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2J2 UBE2K UBE2L3 UBE2N VDAC2 WIBG WNK1 WNK4 YWHAG YWHAZ YY1 ZADH2 ZAK ZC3HAV1L ZDHHC3 31 interactors: BRAF CAMKK1 CARHSP1 CDKN1B CREB1 FANCA FOXO3 GADD45G GSK3A GSK3B IKBKG KCNJ1 KPNA2 MAGEA1 MAPK7 MAPT MLLT3 NDRG1 NEDD4 NEDD4L NEK6 PDK1 PDK2 PDPK1 PIK3CA PPP2CA RABAC1 RICTOR SLC1A3 SLC9A3R2 TMEM184C
Entrez ID 23327 6446
HPRD ID 05903 04264
Ensembl ID ENSG00000049759 ENSG00000118515
Uniprot IDs B7Z2P9 B7Z6K0 F5H602 Q96PU5 E9PR89 O00141
PDB IDs 2LAJ 2LB2 2LTY 2NSQ 2ONI 3JVZ 3JW0 2R5T 3HDM 3HDN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
2cl  antihypertensive  cotransporter  defective  demonstrating  emerging  enac  exchanger  highlight  hypertension  interactor  interesting  liddle  ligase  makes  na  ncc  nephron  nhe3  nkcc2  originally  progress  salt  sensitive  thiazide  transporters  ubiquitin  ubiquitylates 
apical  autophosphorylate  autophosphorylation  c4  cer  ceramide  cf  cftr  chloride  coincidently  conductance  corrects  cystic  defect  deltaf508  explants  folding  hypersecretion  inactivates  mutual  pdk1  permit  phosphorylates  physiologically  ser  suppresses  thr  traffic  trafficking 
Tagcloud (Difference) ?
2cl  antihypertensive  cotransporter  defective  demonstrating  emerging  enac  exchanger  highlight  hypertension  interactor  interesting  liddle  ligase  makes  na  ncc  nephron  nhe3  nkcc2  originally  progress  salt  sensitive  thiazide  transporters  ubiquitin  ubiquitylates 
apical  autophosphorylate  autophosphorylation  c4  cer  ceramide  cf  cftr  chloride  coincidently  conductance  corrects  cystic  defect  deltaf508  explants  folding  hypersecretion  inactivates  mutual  pdk1  permit  phosphorylates  physiologically  ser  suppresses  thr  traffic  trafficking 
Tagcloud (Intersection) ?