NEDD4L and APEX2

  • Number of citations of the paper that reports this interaction (PMID 19953087)
  • 25

NEDD4L

APEX2

Gene Name neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Insomnia (caffeine-induced) ( 22754043)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 22001757)
  • Response to amphetamines ( 22952603)
Protein-Protein Interactions 126 interactors: AATF ABL1 ABL2 ACVR1B ACY3 ADAP2 AICDA AKT3 APEX2 ARHGDIA AURKC BBX BMPR1A BRAF C7orf50 CACNB1 CAMK1D CDC34 CDK3 CDK5 CLIC2 CUEDC1 CYBRD1 CYP26B1 DAPK3 DAZAP2 DDX54 DECR2 DMTN DYRK3 EFEMP2 FGF12 FKBP3 GORAB H1F0 HAX1 HGS IFRD2 IKBKB KCNAB1 KCNAB2 KCNAB3 KCNB1 KIF3B KIFC3 LAPTM5 MAGEB1 MAP2 MAP3K2 MAP3K3 MAP3K5 MAPKAPK3 MARK2 MERTK MINK1 MOB3A MRPL19 NDFIP2 NHP2 NR3C1 NSRP1 NTRK1 NUDT16L1 PBX1 PRKX PRR16 PRRG1 PSMD4 RANBP10 RASL10B RASL11B RNF11 RNF7 ROBO3 RPL30 RPS6KB2 SCAMP3 SCD SCN5A SCNN1A SCNN1B SCNN1G SENP2 SERPINF1 SGK1 SGK2 SIVA1 SLC7A7 SMAD2 SMAD3 SMAD7 SNCA SPAG8 SRMS STAC STK40 TAF1B TARBP2 TBC1D7 TCEAL2 TGFB1I1 TMA16 TMEM55A TRIM41 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2J2 UBE2K UBE2L3 UBE2N VDAC2 WIBG WNK1 WNK4 YWHAG YWHAZ YY1 ZADH2 ZAK ZC3HAV1L ZDHHC3 11 interactors: APP CALCOCO2 CCDC85B EFEMP2 HOOK2 NEDD4L NINL PCNA PGR TRAF2 TRIM37
Entrez ID 23327 27301
HPRD ID 05903 06442
Ensembl ID ENSG00000049759
Uniprot IDs B7Z2P9 B7Z6K0 F5H602 Q96PU5 B4DWI9 B7ZA71 E5KN95 Q9UBZ4
PDB IDs 2LAJ 2LB2 2LTY 2NSQ 2ONI 3JVZ 3JW0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
2cl  antihypertensive  cotransporter  defective  demonstrating  emerging  enac  exchanger  highlight  hypertension  interactor  interesting  liddle  ligase  makes  na  ncc  nephron  nhe3  nkcc2  originally  progress  salt  sensitive  thiazide  transporters  ubiquitin  ubiquitylates 
applications  catalytic  display  efficiency  electron  enabling  endoplasmic  engineered  enrichment  evolution  far  labeling  live  localization  microscopy  micu1  permits  peroxidase  precludes  promiscuous  proteomics  requiring  resolve  reticulum  submitochondrial  superior  tag  yeast 
Tagcloud (Difference) ?
2cl  antihypertensive  cotransporter  defective  demonstrating  emerging  enac  exchanger  highlight  hypertension  interactor  interesting  liddle  ligase  makes  na  ncc  nephron  nhe3  nkcc2  originally  progress  salt  sensitive  thiazide  transporters  ubiquitin  ubiquitylates 
applications  catalytic  display  efficiency  electron  enabling  endoplasmic  engineered  enrichment  evolution  far  labeling  live  localization  microscopy  micu1  permits  peroxidase  precludes  promiscuous  proteomics  requiring  resolve  reticulum  submitochondrial  superior  tag  yeast 
Tagcloud (Intersection) ?