HSPB2 and MT-CO2

Number of citations of the paper that reports this interaction (PubMedID 26465331)
76

Data Source:
BioGRID (two hybrid)

		HSPB2	MT-CO2
Description		heat shock protein family B (small) member 2	cytochrome c oxidase subunit II
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Mitochondrial Membrane Respiratory Chain Complex IV
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Enzyme Activator Activity Unfolded Protein Binding	Cytochrome-c Oxidase Activity Copper Ion Binding Protein Binding Oxidoreductase Activity Metal Ion Binding
	Biological Process	Response To Unfolded Protein Somatic Muscle Development Response To Heat Protein Refolding Negative Regulation Of Apoptotic Process	Response To Hypoxia Mitochondrial Electron Transport, Cytochrome C To Oxygen Lactation Electron Transport Chain ATP Synthesis Coupled Electron Transport Cellular Respiration Response To Ethanol Proton Transmembrane Transport
Pathways			Mitochondrial translation termination TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1 Mitochondrial protein degradation Complex IV assembly
Drugs			Cholic Acid N-Formylmethionine Talmapimod
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		108 interacting genes: A1CF A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATP5F1A ATP6V1E1 B2M BAG3 BEX2 BEX4 BGN BICRAL C1QA CAPZA2 CEP19 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DMPK DUSP1 EEF1A1 EIF4A2 ENKD1 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HOXB9 HSPB3 HSPB8 KANK2 LGALS1 LMO1 LMO3 MAPKAPK5 MB MCCC2 MDH1 MISP MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PATZ1 PGM1 PKP2 POGZ PPM1K PRR35 RFPL3 RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 SNX18 TATDN1 TCAP THEMIS2 THUMPD2 TLX3 TNNI3 TTN TXNIP UBL5 VEZF1 WDR1 WWOX YPEL3 ZNF335	11 interacting genes: CCNG1 ECT2 EGFR HSPB2 LIG4 PSMA1 RAD21 RIDA SHANK3 VHL YWHAE
Entrez ID		3316	4513
HPRD ID		03712	02470
Ensembl ID		ENSG00000170276	ENSG00000198712
Uniprot IDs		A8KAH6 Q16082	P00403 U5Z487
PDB IDs		6F2R	3VRJ 5Z62
Enriched GO Terms of Interacting Partners?		Sarcomere Organization Sarcomere M Band Z Disc Striated Muscle Contraction Actomyosin Structure Organization Cardiac Muscle Tissue Morphogenesis Actin-mediated Cell Contraction Muscle Contraction ATP Metabolic Process Cardiac Muscle Contraction Generation Of Precursor Metabolites And Energy Skeletal Muscle Thin Filament Assembly Muscle Tissue Morphogenesis Actin Filament-based Process Actin-myosin Filament Sliding Muscle System Process Actin Filament-based Movement Cytoplasm Actin Cytoskeleton Organization I Band Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Cytoskeleton Organization Extracellular Exosome Actin Cytoskeleton Purine Ribonucleotide Metabolic Process Muscle Filament Sliding Nucleotide Metabolic Process Respiratory Electron Transport Chain Purine Nucleotide Metabolic Process Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Electron Transport Chain Cellular Respiration Mitochondrion Monocarboxylic Acid Metabolic Process Cardiac Myofibril Small Molecule Metabolic Process Purine-containing Compound Metabolic Process Ventricular Cardiac Muscle Tissue Morphogenesis Nucleoside Phosphate Metabolic Process Glycolytic Process Cardiac Muscle Hypertrophy ADP Catabolic Process Nucleobase-containing Small Molecule Metabolic Process Tertiary Granule Lumen Purine Ribonucleoside Diphosphate Catabolic Process Response To Hypoxia Protein Refolding	Cell Division Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Cell Morphogenesis Nucleus Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly Positive Regulation Of Cell Cycle Process Positive Regulation Of Fibroblast Proliferation Multivesicular Body, Internal Vesicle Lumen MAPK Cascade Establishment Of Integrated Proviral Latency 2-iminopropanoate Deaminase Activity 2-iminobutanoate/2-iminopropanoate Deaminase L-threonine Catabolic Process To Glycine RNA Endonuclease Activity Producing 3'-phosphomonoesters, Hydrolytic Mechanism 2-iminobutanoate Deaminase Activity Positive Regulation Of Nucleocytoplasmic Transport Cytoplasm Regulation Of Protein Phosphorylation Centralspindlin Complex Cellular Response To Stress Cellular Response To Ionizing Radiation Positive Regulation Of Cell Differentiation Positive Regulation Of Cell Cycle Positive Regulation Of Intracellular Protein Transport Regulation Of Cell Differentiation Cytosol Enzyme Binding Protein Phosphatase Binding Positive Regulation Of Protein Kinase C Signaling Regulation Of Fibroblast Proliferation Epidermal Growth Factor Receptor Activity Shc-EGFR Complex Response To Heat DNA Ligase (ATP) Activity DNA Ligase IV Complex Establishment Of Viral Latency DNA Ligase Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Establishment Of Meiotic Sister Chromatid Cohesion Regulation Of Heart Rate By Hormone Scaffold Protein Binding L-threonine Catabolic Process Threonine Metabolic Process Guanylate Kinase-associated Protein Clustering Positive Regulation Of Synapse Structural Plasticity Striatal Medium Spiny Neuron Differentiation Positive Regulation Of Chromosome Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?