MT-CO2

Description		cytochrome c oxidase subunit II
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Mitochondrial Membrane Respiratory Chain Complex IV
	Molecular Function	Cytochrome-c Oxidase Activity Copper Ion Binding Protein Binding Oxidoreductase Activity Metal Ion Binding
	Biological Process	Response To Hypoxia Mitochondrial Electron Transport, Cytochrome C To Oxygen Lactation Electron Transport Chain ATP Synthesis Coupled Electron Transport Cellular Respiration Response To Ethanol Proton Transmembrane Transport
Pathways		Mitochondrial translation termination TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1 Mitochondrial protein degradation Complex IV assembly
Drugs		Cholic Acid N-Formylmethionine Talmapimod
Diseases
GWAS
Interacting Genes		11 interacting genes: CCNG1 ECT2 EGFR HSPB2 LIG4 PSMA1 RAD21 RIDA SHANK3 VHL YWHAE
Entrez ID		4513
HPRD ID		02470
Ensembl ID		ENSG00000198712
Uniprot IDs		P00403 U5Z487
PDB IDs		3VRJ 5Z62
Enriched GO Terms of Interacting Partners?		Cell Division Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Cell Morphogenesis Nucleus Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly Positive Regulation Of Cell Cycle Process Positive Regulation Of Fibroblast Proliferation Multivesicular Body, Internal Vesicle Lumen MAPK Cascade Establishment Of Integrated Proviral Latency 2-iminopropanoate Deaminase Activity 2-iminobutanoate/2-iminopropanoate Deaminase L-threonine Catabolic Process To Glycine RNA Endonuclease Activity Producing 3'-phosphomonoesters, Hydrolytic Mechanism 2-iminobutanoate Deaminase Activity Positive Regulation Of Nucleocytoplasmic Transport Cytoplasm Regulation Of Protein Phosphorylation Centralspindlin Complex Cellular Response To Stress Cellular Response To Ionizing Radiation Positive Regulation Of Cell Differentiation Positive Regulation Of Cell Cycle Positive Regulation Of Intracellular Protein Transport Regulation Of Cell Differentiation Cytosol Enzyme Binding Protein Phosphatase Binding Positive Regulation Of Protein Kinase C Signaling Regulation Of Fibroblast Proliferation Epidermal Growth Factor Receptor Activity Shc-EGFR Complex Response To Heat DNA Ligase (ATP) Activity DNA Ligase IV Complex Establishment Of Viral Latency DNA Ligase Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Establishment Of Meiotic Sister Chromatid Cohesion Regulation Of Heart Rate By Hormone Scaffold Protein Binding L-threonine Catabolic Process Threonine Metabolic Process Guanylate Kinase-associated Protein Clustering Positive Regulation Of Synapse Structural Plasticity Striatal Medium Spiny Neuron Differentiation Positive Regulation Of Chromosome Organization
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