COX2 and RAD21

Number of citations of the paper that reports this interaction (PMID 22145905)
3

Data Source:
BioGRID (two hybrid)

		COX2	RAD21
Gene Name		cytochrome c oxidase subunit II	RAD21 homolog (S. pombe)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Chromosome, Centromeric Region Chromatin Nucleoplasm Chromosome Cytosol Cohesin Complex Membrane Nuclear Meiotic Cohesin Complex
	Molecular Function		Protein Binding
	Biological Process		Mitotic Cell Cycle Double-strand Break Repair DNA Recombination Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Chromosome Segregation Mitotic Nuclear Division Reciprocal Meiotic Recombination Cell Division Protein Localization To Chromatin
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport Orphan transporters	Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Meiotic synapsis Cohesin Loading onto Chromatin Mitotic Anaphase S Phase M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CCNG1 ECT2 EGFR HRSP12 LIG4 PSMA1 RAD21 YWHAE	28 interactors: CAPN1 CASP7 CFL1 COX2 CSTB DISC1 DYNLT1 FHL3 FLNB HNRNPH2 IL7R MSRB2 NUMA1 PPP1R15A PPP1R15B RPL10 RPL13 RPL35A SMARCA5 SMC1A SSU72 STAG1 STAG2 TMSB4X TNFRSF14 WAPAL WNT2B ZNF80
Entrez ID		4513	5885
HPRD ID		02470	05924
Ensembl ID			ENSG00000164754
Uniprot IDs		P00403 Q7GXZ8	O60216
PDB IDs		3VRJ
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Regulation Of Apoptotic Process Mitotic Cell Cycle Cellular Response To Stress Regulation Of Cell Death Apoptotic Process Cell Division Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cell Death Death Response To Stress Regulation Of Protein Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Neurotrophin Signaling Pathway Positive Regulation Of Intracellular Transport Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Cellular Response To DNA Damage Stimulus Negative Regulation Of Apoptotic Process Response To Metal Ion Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Central Nervous System Development Negative Regulation Of Cell Death Positive Regulation Of Fibroblast Proliferation Regulation Of Mitotic Cell Cycle Response To Abiotic Stimulus Regulation Of Intracellular Transport Alkanesulfonate Metabolic Process DNA Ligation Involved In DNA Recombination Negative Regulation Of Cell Cycle Response To Radiation Nervous System Development Response To Inorganic Substance Regulation Of Catalytic Activity Mitotic DNA Damage Checkpoint Positive Regulation Of Protein Import Into Nucleus Regulation Of Fibroblast Proliferation Positive Regulation Of Signal Transduction Mitotic DNA Integrity Checkpoint Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Viral Process Response To Calcium Ion	Cell Division Mitotic Nuclear Division Cellular Protein Localization Viral Life Cycle Cytoskeleton Organization Mitotic Cell Cycle Process Negative Regulation Of DNA Endoreduplication Protein Localization To Endoplasmic Reticulum Cell Cycle Process Mitotic Cell Cycle Organelle Organization Protein Localization To Organelle Negative Regulation Of DNA Replication MRNA Metabolic Process Viral Process Protein Localization Cellular Localization Cellular Protein Complex Disassembly Regulation Of DNA Endoreduplication Protein Complex Disassembly Cell Cycle Negative Regulation Of Cell Cycle Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Establishment Of Cell Polarity Negative Regulation Of DNA Metabolic Process Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of DNA Replication Sister Chromatid Cohesion Establishment Of Mitotic Spindle Orientation Actin Cytoskeleton Organization Translational Termination Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Protein Localization To Organelle Nuclear-transcribed MRNA Catabolic Process Actin Filament-based Process MRNA Catabolic Process Protein Targeting To Membrane Establishment Or Maintenance Of Cell Polarity Viral Entry Into Host Cell Translational Elongation Spindle Localization Regulation Of Metabolic Process Entry Into Host Cell RNA Catabolic Process Positive Regulation Of Translational Initiation In Response To Stress
Tagcloud ?		cadherin cancers cd44 center character characteristics chi2 clinic colon colorectal differentiated feature features gender histological hmlh1 hmsh2 ki meanwhile mucinous protection rates rectal right shanghai sided signet subsides vs	aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad27 runx1 scgb2a2 snai1 snai2 top2a younger
Tagcloud (Difference) ?		cadherin cancers cd44 center character characteristics chi2 clinic colon colorectal differentiated feature features gender histological hmlh1 hmsh2 ki meanwhile mucinous protection rates rectal right shanghai sided signet subsides vs	aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad27 runx1 scgb2a2 snai1 snai2 top2a younger
Tagcloud (Intersection) ?