HIST1H1A and PTMA

Number of citations of the paper that reports this interaction (PMID 8814229)
9

Data Source:
HPRD (in vitro)

		HIST1H1A	PTMA
Gene Name		histone cluster 1, H1a	prothymosin, alpha
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nuclear Chromatin Nuclear Euchromatin	Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Chromatin DNA Binding	Protein Binding
	Biological Process	Nucleosome Assembly Spermatogenesis	Transcription, DNA-templated
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Activation of DNA fragmentation factor Apoptosis induced DNA fragmentation Cellular Senescence Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS			Eating disorders (purging via substances) ( 23568457) Height ( 18391951)
Protein-Protein Interactions		45 interactors: AEBP2 CCNA1 CCNA2 CCNB1 CCND2 CCNE1 CDK1 CDK2 CDK4 CDK6 CDK7 CDKN1B CRP CTCFL EED EHMT2 EP300 EZH2 GADD45A GZMA IRAK4 KAT2B LIMK1 LIMK2 LOX NAP1L4 NASP PARP1 PARP3 PELP1 PKN1 PRDM1 PRKCA PRKCB PRKCD PRKCE PRKCZ PRKDC PTMA RBBP4 SUZ12 TERF1 TERF2IP TLK1 WHSC1L1	41 interactors: CASP3 CASP7 CCNA2 CCNB1 CDK1 CDK2 CDK4 CREBBP EP300 ESR1 HDAC1 HDAC2 HIST1H1A HIST1H2AJ HIST1H2BG HIST1H4A HIST2H2BE HIST2H3C HIST2H4A HIST3H3 HSPA1A IL7R KEAP1 KPNA2 KPNB1 NCOR1 NUP62 NUPR1 NUTF2 PCNA PHB2 RAN RCC1 SET SIN3A STAT3 TERF1 TERF2 TERF2IP VIPR1 ZDHHC17
Entrez ID		3024	5757
HPRD ID		00820	01778
Ensembl ID		ENSG00000124610	ENSG00000187514
Uniprot IDs		Q02539	P06454 Q53S24
PDB IDs			2L9I
Enriched GO Terms of Interacting Partners?		Chromosome Organization Cell Cycle Chromatin Organization Chromatin Modification Regulation Of Cell Cycle Organelle Organization Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Histone Modification Regulation Of Metabolic Process Mitotic Cell Cycle Process Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Kinase Activity Regulation Of Phosphorylation Regulation Of Nitrogen Compound Metabolic Process Cellular Protein Metabolic Process G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Protein Phosphorylation Regulation Of Mitotic Cell Cycle Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Cell Division Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle DNA Metabolic Process Cellular Response To Stress Response To Stress Histone Phosphorylation Regulation Of Catalytic Activity Peptidyl-amino Acid Modification Cellular Metabolic Process Regulation Of Cell Cycle Process Phosphorylation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression, Epigenetic	Chromosome Organization Chromatin Organization Organelle Organization DNA Metabolic Process Chromatin Modification Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Telomere Maintenance Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Histone Modification DNA Packaging Regulation Of Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cell Cycle Negative Regulation Of Gene Expression, Epigenetic Response To Organic Substance Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Proliferation Protein Complex Assembly Response To Stimulus Mitotic Cell Cycle Process Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression DNA Replication Viral Process DNA Conformation Change Negative Regulation Of Biosynthetic Process Homeostatic Process Regulation Of Protein Metabolic Process Rhythmic Process Regulation Of Chromosome Organization G2/M Transition Of Mitotic Cell Cycle Cellular Response To Stimulus Nucleosome Assembly Regulation Of RNA Metabolic Process Cell Cycle Process Cellular Response To Stress Regulation Of Cell Death Chromatin Assembly
Tagcloud ?			adjacent advanced ajcc assessment colon crc depth dfs distant help hence invasion lnm lymph metastasis mutant node os overexpression plays predict prognosis prothymosin survival tissue tp53 translational triggers tumorigenesis
Tagcloud (Difference) ?			adjacent advanced ajcc assessment colon crc depth dfs distant help hence invasion lnm lymph metastasis mutant node os overexpression plays predict prognosis prothymosin survival tissue tp53 translational triggers tumorigenesis
Tagcloud (Intersection) ?