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HIST1H1A and PTMA
Number of citations of the paper that reports this interaction (PMID
8814229
)
9
Data Source:
HPRD
(in vitro)
HIST1H1A
PTMA
Gene Name
histone cluster 1, H1a
prothymosin, alpha
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleosome
Nuclear Chromatin
Nuclear Euchromatin
Nucleus
Nucleoplasm
Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Chromatin DNA Binding
Protein Binding
Biological Process
Nucleosome Assembly
Spermatogenesis
Transcription, DNA-templated
Pathways
DNA Damage/Telomere Stress Induced Senescence
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Activation of DNA fragmentation factor
Apoptosis induced DNA fragmentation
Cellular Senescence
Programmed Cell Death
Apoptotic execution phase
Drugs
Diseases
GWAS
Eating disorders (purging via substances) (
23568457
)
Height (
18391951
)
Protein-Protein Interactions
45 interactors:
AEBP2
CCNA1
CCNA2
CCNB1
CCND2
CCNE1
CDK1
CDK2
CDK4
CDK6
CDK7
CDKN1B
CRP
CTCFL
EED
EHMT2
EP300
EZH2
GADD45A
GZMA
IRAK4
KAT2B
LIMK1
LIMK2
LOX
NAP1L4
NASP
PARP1
PARP3
PELP1
PKN1
PRDM1
PRKCA
PRKCB
PRKCD
PRKCE
PRKCZ
PRKDC
PTMA
RBBP4
SUZ12
TERF1
TERF2IP
TLK1
WHSC1L1
41 interactors:
CASP3
CASP7
CCNA2
CCNB1
CDK1
CDK2
CDK4
CREBBP
EP300
ESR1
HDAC1
HDAC2
HIST1H1A
HIST1H2AJ
HIST1H2BG
HIST1H4A
HIST2H2BE
HIST2H3C
HIST2H4A
HIST3H3
HSPA1A
IL7R
KEAP1
KPNA2
KPNB1
NCOR1
NUP62
NUPR1
NUTF2
PCNA
PHB2
RAN
RCC1
SET
SIN3A
STAT3
TERF1
TERF2
TERF2IP
VIPR1
ZDHHC17
Entrez ID
3024
5757
HPRD ID
00820
01778
Ensembl ID
ENSG00000124610
ENSG00000187514
Uniprot IDs
Q02539
P06454
Q53S24
PDB IDs
2L9I
Enriched GO Terms of Interacting Partners
?
Chromosome Organization
Cell Cycle
Chromatin Organization
Chromatin Modification
Regulation Of Cell Cycle
Organelle Organization
Cell Cycle Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Cellular Protein Modification Process
Regulation Of Cellular Protein Metabolic Process
Histone Modification
Regulation Of Metabolic Process
Mitotic Cell Cycle Process
Regulation Of Protein Metabolic Process
Regulation Of Protein Kinase Activity
Regulation Of Protein Phosphorylation
Mitotic Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Kinase Activity
Regulation Of Phosphorylation
Regulation Of Nitrogen Compound Metabolic Process
Cellular Protein Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Metabolic Process
Regulation Of Phosphorus Metabolic Process
Protein Phosphorylation
Regulation Of Mitotic Cell Cycle
Protein Metabolic Process
G1/S Transition Of Mitotic Cell Cycle
Cell Division
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Gene Expression
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Cell Cycle
DNA Metabolic Process
Cellular Response To Stress
Response To Stress
Histone Phosphorylation
Regulation Of Catalytic Activity
Peptidyl-amino Acid Modification
Cellular Metabolic Process
Regulation Of Cell Cycle Process
Phosphorylation
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Cell Cycle
Regulation Of Cellular Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression, Epigenetic
Chromosome Organization
Chromatin Organization
Organelle Organization
DNA Metabolic Process
Chromatin Modification
Mitotic Cell Cycle
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Telomere Maintenance
Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Histone Modification
DNA Packaging
Regulation Of Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Cell Cycle
Negative Regulation Of Gene Expression, Epigenetic
Response To Organic Substance
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Proliferation
Protein Complex Assembly
Response To Stimulus
Mitotic Cell Cycle Process
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
DNA Replication
Viral Process
DNA Conformation Change
Negative Regulation Of Biosynthetic Process
Homeostatic Process
Regulation Of Protein Metabolic Process
Rhythmic Process
Regulation Of Chromosome Organization
G2/M Transition Of Mitotic Cell Cycle
Cellular Response To Stimulus
Nucleosome Assembly
Regulation Of RNA Metabolic Process
Cell Cycle Process
Cellular Response To Stress
Regulation Of Cell Death
Chromatin Assembly
Tagcloud
?
adjacent
advanced
ajcc
assessment
colon
crc
depth
dfs
distant
help
hence
invasion
lnm
lymph
metastasis
mutant
node
os
overexpression
plays
predict
prognosis
prothymosin
survival
tissue
tp53
translational
triggers
tumorigenesis
Tagcloud (Difference)
?
adjacent
advanced
ajcc
assessment
colon
crc
depth
dfs
distant
help
hence
invasion
lnm
lymph
metastasis
mutant
node
os
overexpression
plays
predict
prognosis
prothymosin
survival
tissue
tp53
translational
triggers
tumorigenesis
Tagcloud (Intersection)
?