PTMA and NUTF2

Number of citations of the paper that reports this interaction (PubMedID 11310559)
0

Data Source:
HPRD (in vitro)

		PTMA	NUTF2
Description		prothymosin alpha	nuclear transport factor 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Nuclear Inner Membrane Nuclear Outer Membrane Nuclear Pore Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome
	Molecular Function	Protein Binding Histone Binding DNA-binding Transcription Factor Binding Histone Chaperone Activity	Protein Binding Structural Constituent Of Nuclear Pore Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Chromatin Organization DNA-templated Transcription Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Protein Transport MRNA Transport Protein Localization To Nuclear Pore
Pathways
Drugs
Diseases
GWAS		Eating disorders (purging via substances) ( 23568457) Height ( 18391951) Lymphocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) White blood cell count ( 27863252 32888494)	Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		43 interacting genes: CASP3 CASP7 CCNA2 CCNB1 CDK1 CDK2 CDK4 CREBBP EP300 ESR1 FNDC3B GSK3A H1-1 H2AC14 H2BC21 H2BC8 H3-4 H3C14 H4C1 H4C14 HDAC1 HDAC2 HSPA1A IL7R KEAP1 KPNA2 KPNB1 NCOR1 NUP62 NUPR1 NUTF2 PCNA PHB2 RAN RCC1 SET SIN3A STAT3 TERF1 TERF2 TERF2IP VIPR1 ZDHHC17	48 interacting genes: BEND7 BRWD1 CAMK2G CCDC106 CCDC150 CCDC158 CEBPA CHCHD3 CHMP4A CKMT1A CKMT1B CLPP FAM50B HMG20A HMG20B KHDC4 KRT86 KRTAP9-8 LASP1 LCE1C LCE5A LENG1 LUC7L2 MRNIP MYOZ3 NME1 NME4 NRIP3 NUP54 NUP62 PAX4 PBX4 PCNA PFKP PHF11 PPP1R16A PTMA RAN RPRD1B SPATC1L SPRY4 TEX35 THAP11 THAP3 TLE5 UBAP2 YAF2 ZMAT2
Entrez ID		5757	10204
HPRD ID		01778	12050
Ensembl ID		ENSG00000187514	ENSG00000102898
Uniprot IDs		P06454 Q53S24	P61970
PDB IDs		2L9I 2MNQ	1GY5
Enriched GO Terms of Interacting Partners?		Nucleoplasm Chromatin Organization Chromatin Remodeling Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Chromosome, Telomeric Region Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Binding Protein Localization To Organelle Chromosome Organization Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Nucleosome Assembly Protein-containing Complex Regulation Of Primary Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Protein Import Into Nucleus Rhythmic Process Negative Regulation Of Biosynthetic Process Chromosome Import Into Nucleus Telomere Organization Protein-DNA Complex Assembly Nucleosome Organization Regulation Of Macromolecule Biosynthetic Process Structural Constituent Of Chromatin Nuclear Telomere Cap Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Protein Localization To Chromosome Protein Localization To Nucleus Positive Regulation Of Macromolecule Metabolic Process Nucleosome Positive Regulation Of Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of DNA Metabolic Process Regulation Of Gene Expression Chromatin Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Cell Population Proliferation G1/S Transition Of Mitotic Cell Cycle Regulation Of Programmed Cell Death DNA Binding	Protein Binding Protein-containing Complex Binding Phosphocreatine Biosynthetic Process Creatine Kinase Activity GTP Metabolic Process Nuclear Pore Nuclear Pore Central Transport Channel Nucleus UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process Nucleoplasm Protein Hexamerization Negative Regulation Of Protein Sumoylation Male Germ Cell Nucleus CTP Biosynthetic Process CTP Metabolic Process
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