HIST1H1A and LOX

Number of citations of the paper that reports this interaction (PMID 12686141)
7

Data Source:
BioGRID (pull down)

		HIST1H1A	LOX
Gene Name		histone cluster 1, H1a	lysyl oxidase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nuclear Chromatin Nuclear Euchromatin	Extracellular Region Proteinaceous Extracellular Matrix Collagen Trimer Extracellular Space Nucleus
	Molecular Function	Protein Binding Chromatin DNA Binding	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding
	Biological Process	Nucleosome Assembly Spermatogenesis	Blood Vessel Development Cellular Protein Modification Process Extracellular Matrix Organization Collagen Fibril Organization Lung Development Wound Healing Response To Drug Elastic Fiber Assembly Response To Steroid Hormone Oxidation-reduction Process
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Activation of DNA fragmentation factor Apoptosis induced DNA fragmentation Cellular Senescence Programmed Cell Death Apoptotic execution phase	Collagen formation Crosslinking of collagen fibrils Elastic fibre formation Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS			Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Protein-Protein Interactions		45 interactors: AEBP2 CCNA1 CCNA2 CCNB1 CCND2 CCNE1 CDK1 CDK2 CDK4 CDK6 CDK7 CDKN1B CRP CTCFL EED EHMT2 EP300 EZH2 GADD45A GZMA IRAK4 KAT2B LIMK1 LIMK2 LOX NAP1L4 NASP PARP1 PARP3 PELP1 PKN1 PRDM1 PRKCA PRKCB PRKCD PRKCE PRKCZ PRKDC PTMA RBBP4 SUZ12 TERF1 TERF2IP TLK1 WHSC1L1	7 interactors: DHDDS DPT ELN HIST1H1A HIST1H1B HIST1H2BJ HIST2H2BE
Entrez ID		3024	4015
HPRD ID		00820	01087
Ensembl ID		ENSG00000124610	ENSG00000113083
Uniprot IDs		Q02539	B7ZAJ4 D0PNI2 P28300
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromosome Organization Cell Cycle Chromatin Organization Chromatin Modification Regulation Of Cell Cycle Organelle Organization Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Histone Modification Regulation Of Metabolic Process Mitotic Cell Cycle Process Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Kinase Activity Regulation Of Phosphorylation Regulation Of Nitrogen Compound Metabolic Process Cellular Protein Metabolic Process G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Protein Phosphorylation Regulation Of Mitotic Cell Cycle Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Cell Division Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle DNA Metabolic Process Cellular Response To Stress Response To Stress Histone Phosphorylation Regulation Of Catalytic Activity Peptidyl-amino Acid Modification Cellular Metabolic Process Regulation Of Cell Cycle Process Phosphorylation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression, Epigenetic	Nucleosome Assembly Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging DNA Conformation Change Innate Immune Response In Mucosa Cellular Macromolecular Complex Assembly Antibacterial Humoral Response Chromatin Organization Antimicrobial Humoral Response Mucosal Immune Response Cellular Component Assembly Chromosome Organization Protein Complex Assembly Defense Response To Gram-positive Bacterium Organelle Organization Defense Response To Bacterium Dolichyl Diphosphate Biosynthetic Process Establishment Of Protein Localization To Chromatin Humoral Immune Response Protein Localization To Chromatin Positive Regulation Of Histone H3-K9 Methylation Stress Fiber Assembly Extracellular Matrix Organization Extracellular Structure Organization Response To Bacterium Protein Localization To Chromosome Positive Regulation Of Histone Methylation
Tagcloud ?			aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?			aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?