PTMA

Gene Name		prothymosin, alpha
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding
	Biological Process	Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Eating disorders (purging via substances) ( 23568457) Height ( 18391951)
Protein-protein Interactions		41 interactors: CASP3 CASP7 CCNA2 CCNB1 CDK1 CDK2 CDK4 CREBBP EP300 ESR1 HDAC1 HDAC2 HIST1H1A HIST1H2AJ HIST1H2BG HIST1H4A HIST2H2BE HIST2H3C HIST2H4A HIST3H3 HSPA1A IL7R KEAP1 KPNA2 KPNB1 NCOR1 NUP62 NUPR1 NUTF2 PCNA PHB2 RAN RCC1 SET SIN3A STAT3 TERF1 TERF2 TERF2IP VIPR1 ZDHHC17
Entrez ID		5757
HPRD ID		01778
Ensembl ID		ENSG00000187514
Uniprot IDs		P06454 Q53S24
PDB IDs		2L9I
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Organization Organelle Organization DNA Metabolic Process Chromatin Modification Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Telomere Maintenance Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Histone Modification DNA Packaging Regulation Of Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cell Cycle Negative Regulation Of Gene Expression, Epigenetic Response To Organic Substance Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Proliferation Protein Complex Assembly Response To Stimulus Mitotic Cell Cycle Process Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression DNA Replication Viral Process DNA Conformation Change Negative Regulation Of Biosynthetic Process Homeostatic Process Regulation Of Protein Metabolic Process Rhythmic Process Regulation Of Chromosome Organization G2/M Transition Of Mitotic Cell Cycle Cellular Response To Stimulus Nucleosome Assembly Regulation Of RNA Metabolic Process Cell Cycle Process Cellular Response To Stress Regulation Of Cell Death Chromatin Assembly
Tagcloud ?		adjacent advanced ajcc assessment colon crc depth dfs distant help hence invasion lnm lymph metastasis mutant node os overexpression plays predict prognosis prothymosin survival tissue tp53 translational triggers tumorigenesis