PTMA and VIPR1

Number of citations of the paper that reports this interaction (PMID 8886855)
0

Data Source:
HPRD (in vitro)

		PTMA	VIPR1
Gene Name		prothymosin, alpha	vasoactive intestinal peptide receptor 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Protein Binding	Vasoactive Intestinal Polypeptide Receptor Activity Protein Binding
	Biological Process	Transcription, DNA-templated	Muscle Contraction Immune Response G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Synaptic Transmission Digestion Positive Regulation Of Cell Proliferation
Pathways			Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events
Drugs
Diseases
GWAS		Eating disorders (purging via substances) ( 23568457) Height ( 18391951)
Protein-Protein Interactions		41 interactors: CASP3 CASP7 CCNA2 CCNB1 CDK1 CDK2 CDK4 CREBBP EP300 ESR1 HDAC1 HDAC2 HIST1H1A HIST1H2AJ HIST1H2BG HIST1H4A HIST2H2BE HIST2H3C HIST2H4A HIST3H3 HSPA1A IL7R KEAP1 KPNA2 KPNB1 NCOR1 NUP62 NUPR1 NUTF2 PCNA PHB2 RAN RCC1 SET SIN3A STAT3 TERF1 TERF2 TERF2IP VIPR1 ZDHHC17	15 interactors: ADCYAP1 CALM1 GNAI1 GNAQ GNAS GPRASP1 PFN1 PTMA RAMP1 RAMP2 RAMP3 SCT TINF2 VIP WASL
Entrez ID		5757	7433
HPRD ID		01778	01890
Ensembl ID		ENSG00000187514	ENSG00000114812
Uniprot IDs		P06454 Q53S24	B4DNY6 P32241
PDB IDs		2L9I	1OF2 1OGT 3B3I
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Organization Organelle Organization DNA Metabolic Process Chromatin Modification Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Telomere Maintenance Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Histone Modification DNA Packaging Regulation Of Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cell Cycle Negative Regulation Of Gene Expression, Epigenetic Response To Organic Substance Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Proliferation Protein Complex Assembly Response To Stimulus Mitotic Cell Cycle Process Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression DNA Replication Viral Process DNA Conformation Change Negative Regulation Of Biosynthetic Process Homeostatic Process Regulation Of Protein Metabolic Process Rhythmic Process Regulation Of Chromosome Organization G2/M Transition Of Mitotic Cell Cycle Cellular Response To Stimulus Nucleosome Assembly Regulation Of RNA Metabolic Process Cell Cycle Process Cellular Response To Stress Regulation Of Cell Death Chromatin Assembly	Positive Regulation Of CAMP Biosynthetic Process Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Adenylate Cyclase Activity G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Lyase Activity G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Body Fluid Levels Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Platelet Activation Receptor Metabolic Process Cellular Localization Activation Of Adenylate Cyclase Activity Establishment Of Localization In Cell Secretion Transport Receptor Internalization Cell Surface Receptor Signaling Pathway Blood Coagulation Hemostasis Regulation Of Protein Localization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Membrane Organization Vesicle-mediated Transport Response To Hormone Regulation Of Phosphorus Metabolic Process Regulation Of Protein Glycosylation Positive Regulation Of Cellular Biosynthetic Process Wound Healing Negative Regulation Of Ion Transport Cell Activation Response To Wounding Protein Localization CAMP Biosynthetic Process Negative Regulation Of Potassium Ion Transport Regulation Of Signal Transduction Protein Localization To Plasma Membrane Response To Lipid Regulation Of Glycoprotein Biosynthetic Process Nitric Oxide Metabolic Process Response To Organic Cyclic Compound
Tagcloud ?		adjacent advanced ajcc assessment colon crc depth dfs distant help hence invasion lnm lymph metastasis mutant node os overexpression plays predict prognosis prothymosin survival tissue tp53 translational triggers tumorigenesis	10k ac calca canonical cervix cervixes checkpoint differentially g2 genomics globally igfbp2 immunological krt17 networks oligomicroarray pheochromocytoma ppargamma rnas scc separated signature signatures splenomegaly transcriptomic transcripts urgent uterine utilized
Tagcloud (Difference) ?		adjacent advanced ajcc assessment colon crc depth dfs distant help hence invasion lnm lymph metastasis mutant node os overexpression plays predict prognosis prothymosin survival tissue tp53 translational triggers tumorigenesis	10k ac calca canonical cervix cervixes checkpoint differentially g2 genomics globally igfbp2 immunological krt17 networks oligomicroarray pheochromocytoma ppargamma rnas scc separated signature signatures splenomegaly transcriptomic transcripts urgent uterine utilized
Tagcloud (Intersection) ?