PTMA and VIPR1

Number of citations of the paper that reports this interaction (PubMedID 8886855)
0

Data Source:
HPRD (in vitro)

		PTMA	VIPR1
Description		prothymosin alpha	vasoactive intestinal peptide receptor 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Plasma Membrane Membrane Receptor Complex
	Molecular Function	Protein Binding Histone Binding DNA-binding Transcription Factor Binding Histone Chaperone Activity	Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Vasoactive Intestinal Polypeptide Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding
	Biological Process	Chromatin Organization DNA-templated Transcription Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation
Pathways			G alpha (s) signalling events Glucagon-type ligand receptors
Drugs
Diseases
GWAS		Eating disorders (purging via substances) ( 23568457) Height ( 18391951) Lymphocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) White blood cell count ( 27863252 32888494)	Bipolar disorder ( 31043756) Cerebrospinal fluid clusterin levels ( 26545630) Hip circumference adjusted for BMI ( 28552196) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)
Interacting Genes		43 interacting genes: CASP3 CASP7 CCNA2 CCNB1 CDK1 CDK2 CDK4 CREBBP EP300 ESR1 FNDC3B GSK3A H1-1 H2AC14 H2BC21 H2BC8 H3-4 H3C14 H4C1 H4C14 HDAC1 HDAC2 HSPA1A IL7R KEAP1 KPNA2 KPNB1 NCOR1 NUP62 NUPR1 NUTF2 PCNA PHB2 RAN RCC1 SET SIN3A STAT3 TERF1 TERF2 TERF2IP VIPR1 ZDHHC17	16 interacting genes: ADCYAP1 CALM1 GNAI1 GNAQ GNAS GPRASP1 PFN1 PRDM5 PTMA RAMP1 RAMP2 RAMP3 SCT TINF2 VIP WASL
Entrez ID		5757	7433
HPRD ID		01778	01890
Ensembl ID		ENSG00000187514	ENSG00000114812
Uniprot IDs		P06454 Q53S24	B4DNY6 P32241
PDB IDs		2L9I 2MNQ	1OF2 1OGT 3B3I 3B6S 3DTX 3HCV 5DEF 5DEG 5IB1 5IB2 5IB3 5IB4 5IB5 6VN7 7ALO 8E3Y 8E3Z
Enriched GO Terms of Interacting Partners?		Nucleoplasm Chromatin Organization Chromatin Remodeling Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Chromosome, Telomeric Region Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Binding Protein Localization To Organelle Chromosome Organization Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Nucleosome Assembly Protein-containing Complex Regulation Of Primary Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Protein Import Into Nucleus Rhythmic Process Negative Regulation Of Biosynthetic Process Chromosome Import Into Nucleus Telomere Organization Protein-DNA Complex Assembly Nucleosome Organization Regulation Of Macromolecule Biosynthetic Process Structural Constituent Of Chromatin Nuclear Telomere Cap Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Protein Localization To Chromosome Protein Localization To Nucleus Positive Regulation Of Macromolecule Metabolic Process Nucleosome Positive Regulation Of Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of DNA Metabolic Process Regulation Of Gene Expression Chromatin Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Cell Population Proliferation G1/S Transition Of Mitotic Cell Cycle Regulation Of Programmed Cell Death DNA Binding	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of CAMP/PKA Signal Transduction Amylin Receptor Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Calcitonin Family Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Guanyl Nucleotide Binding Type 2 Vasoactive Intestinal Polypeptide Receptor Binding Type 1 Vasoactive Intestinal Polypeptide Receptor Binding G-protein Beta/gamma-subunit Complex Binding Response To Prostaglandin E Adrenomedullin Receptor Activity Adrenomedullin Receptor Complex Amylin Receptor Activity Positive Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Heterotrimeric G-protein Complex Adenylate Cyclase Regulator Activity Adenylate Cyclase Activator Activity Adrenomedullin Receptor Signaling Pathway Response To Hormone Coreceptor Activity Regulation Of Peptide Hormone Secretion G Protein Activity Receptor Internalization G Protein-coupled Receptor Binding Peptide Hormone Receptor Binding Activation Of Adenylate Cyclase Activity Regulation Of Signal Transduction Regulation Of Hormone Secretion Regulation Of Hormone Levels Neuropeptide Signaling Pathway Regulation Of Protein Localization Regulation Of Body Fluid Levels Positive Regulation Of Adenylate Cyclase Activity Cellular Response To Acidic PH Hormone Activity Positive Regulation Of Lyase Activity Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Regulation Of Biological Quality Positive Regulation Of Cyclase Activity Regulation Of Metabolic Process G Protein-coupled Serotonin Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Cellular Response To Hormone Stimulus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?