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NR3C1 and SMARCD1
Number of citations of the paper that reports this interaction (PubMedID
12917342
)
49
Data Source:
HPRD
(in vivo, in vitro)
NR3C1
SMARCD1
Description
nuclear receptor subfamily 3 group C member 1
SWI/SNF related BAF chromatin remodeling complex subunit D1
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Centrosome
Spindle
Cytosol
Cytoskeleton
Membrane
Nuclear Speck
Protein-containing Complex
Synapse
Kinetochore
Chromatin
Nucleus
Nucleoplasm
Nuclear Matrix
SWI/SNF Complex
RSC-type Complex
Brahma Complex
NpBAF Complex
NBAF Complex
GBAF Complex
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Core Promoter Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
RNA Binding
Nuclear Receptor Activity
Nuclear Glucocorticoid Receptor Activity
Steroid Binding
Protein Binding
Zinc Ion Binding
Lipid Binding
TBP-class Protein Binding
Protein Kinase Binding
Estrogen Response Element Binding
Identical Protein Binding
Sequence-specific DNA Binding
Metal Ion Binding
Hsp90 Protein Binding
Steroid Hormone Binding
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Chromatin Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
Signaling Receptor Binding
Protein Binding
Molecular Adaptor Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Gluconeogenesis
Chromatin Organization
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Chromosome Segregation
Signal Transduction
Glucocorticoid Metabolic Process
Response To Wounding
Gene Expression
Microglia Differentiation
Adrenal Gland Development
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Regulation Of Glucocorticoid Biosynthetic Process
Nuclear Receptor-mediated Corticosteroid Signaling Pathway
Synaptic Transmission, Glutamatergic
Maternal Behavior
Nuclear Receptor-mediated Glucocorticoid Signaling Pathway
Positive Regulation Of Neuron Apoptotic Process
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Astrocyte Differentiation
Cell Division
Response To Glucocorticoid
Response To Cortisol
Mammary Gland Duct Morphogenesis
Motor Behavior
Cellular Response To Steroid Hormone Stimulus
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Dexamethasone Stimulus
Cellular Response To Transforming Growth Factor Beta Stimulus
Neuroinflammatory Response
Response To Ketone
Positive Regulation Of MiRNA Transcription
Chromatin Organization
Nucleosome Disassembly
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Positive Regulation Of Cell Population Proliferation
Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of T Cell Differentiation
Negative Regulation Of Cell Differentiation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Myoblast Differentiation
Transcription Initiation-coupled Chromatin Remodeling
Positive Regulation Of DNA-templated Transcription
Regulation Of G0 To G1 Transition
Cellular Response To Fatty Acid
Positive Regulation Of Stem Cell Population Maintenance
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Double-strand Break Repair
Regulation Of Nucleotide-excision Repair
Pathways
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
SUMOylation of intracellular receptors
PTK6 Expression
Regulation of RUNX2 expression and activity
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Potential therapeutics for SARS
Regulation of NPAS4 gene transcription
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Formation of the canonical BAF (cBAF) complex
Formation of the polybromo-BAF (pBAF) complex
Formation of the embryonic stem cell BAF (esBAF) complex
Formation of the non-canonical BAF (ncBAF) complex
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Flunisolide
Diflorasone
Alclometasone
Medrysone
Amcinonide
Fluorometholone
Megestrol acetate
Levonorgestrel
Beclomethasone dipropionate
Progesterone
Spironolactone
Betamethasone
Desoximetasone
Fluticasone propionate
Fluocinolone acetonide
Ulobetasol
Triamcinolone
Prednisone
Flumethasone
Fludrocortisone
Norethisterone
Hydrocortisone
Mometasone
Hydrocortamate
Mifepristone
Clocortolone
Flurandrenolide
Prednisolone
Loteprednol etabonate
Rimexolone
Methylprednisolone
Clobetasol propionate
Fluocinonide
Prednicarbate
Fluoxymesterone
Budesonide
Dexamethasone
Desonide
Cortisone acetate
Paramethasone
Drospirenone
Ciclesonide
Hexane-1,6-Diol
Aldosterone
ORG-34517
Difluprednate
Ulipristal
Fluticasone furoate
Tixocortol
Difluocortolone
Gestrinone
Deflazacort
Onapristone
Cortivazol
Clobetasone
Fluticasone
Mometasone furoate
Hydrocortisone aceponate
Hydrocortisone acetate
Hydrocortisone butyrate
Hydrocortisone cypionate
Hydrocortisone phosphate
Hydrocortisone probutate
Hydrocortisone valerate
Segesterone acetate
Prednisolone phosphate
Dexamethasone acetate
Betamethasone phosphate
Prednisolone acetate
Diseases
46,XX disorders of sex development (Disorders related to androgen excess), including: Congenital adrenal hyperplasias; Glucocorticoid resistance; Aromatase deficiency
GWAS
Appendicular lean mass (
33097823
)
Atrial fibrillation (
29892015
30061737
)
Hip circumference adjusted for BMI (
34021172
)
Lymphocyte percentage of white cells (
32888494
)
Neutrophil percentage of white cells (
32888494
)
Night sleep phenotypes (
27126917
)
PR interval (
32439900
)
Spatial processing (
31596458
)
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Interacting Genes
167 interacting genes:
ABCC1
ADA
AR
ARPC5
BAG1
C1orf94
CALM1
CALR
CEBPA
CEBPB
CENPB
CHD9
COPS6
CREB1
CREBBP
DAP3
DAPK1
DCAF6
DDX54
DNMT3L
DOCK3
DTD1
ECD
EFHC2
EGFR
EP300
EPB41L1
ETS1
ETS2
FAM161B
FKBP4
FTH1
FYN
GNB1
GNB2
GRIP1
H3C1
HDAC1
HDAC6
HMGB1
HMGB2
HMOX2
HNRNPA1
HNRNPU
HSP90AA1
HSP90AB1
HSPA1A
HSPD1
IDE
IFNGR2
JMJD1C
JUN
KAT5
KDM5A
KPNA2
KRTCAP3
LCK
LCOR
LPXN
LRIF1
MAFF
MAPK1
MAPK15
MAPK8
MDM2
MED1
MED14
MED25
MSX2
NCL
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOR1
NCOR2
NEDD4L
NFKB1
NFKB2
NR0B1
NR0B2
NR1H3
NR2E3
NR2F2
NR2F6
NR3C2
NR4A1
NRIP1
NUP54
ONECUT1
OSGEP
PBX1
PELP1
PIAS2
POLR1D
POU1F1
POU2F1
POU2F2
PPARGC1A
PRDX3
PRKACA
PRKDC
PRPF6
PSMC3IP
PTGES3
PTMS
RACK1
RAD54L2
RAD9A
RAF1
RAN
RARA
RBM14
RELA
RFPL2
RNF14
RXRB
SFN
SGTA
SHKBP1
SLC25A4
SMAD3
SMARCA2
SMARCA4
SMARCB1
SMARCC1
SMARCD1
SMARCE1
SPIN2A
SRA1
SRC
STAT3
STAT5A
STAT5B
STRN3
STUB1
SUMO1
SUMO4
SVIL
SYT1
TADA2A
TBP
TDG
TGFB1I1
TMF1
TNS4
TP53
TRIM24
TRIM28
TSG101
TXN
UBB
UBE2I
UBE2L3
UBE3A
UBR1
UBR5
UHRF1
USP2
WTIP
YWHAH
ZBTB16
ZBTB20
ZBTB3
ZBTB9
ZNF496
156 interacting genes:
ABI1
ABI2
ABI3
ACTMAP
ADAT2
AIRIM
ANKRD23
ANKRD49
ANKS1A
ANP32B
APOA5
AR
ARMC10
ARRDC3
BCAS2
BEND5
BEX3
BLOC1S5
BRWD1
C4BPA
CALCOCO2
CCDC102B
CCDC197
CCDC33
CCDC85B
CDC5L
CDR2
CDSN
CDX2
CEACAM6
CFTR
CHFR
CHN2
CLNK
COG6
COL1A2
CORO1A
CUEDC1
CYSRT1
DCTN2
DISC1
EGFL7
EIF4G1
ESR1
ESS2
FAM136A
FAM161A
FBXO7
FEZ1
FOS
FUS
GATA1
GCC1
GIGYF1
GINS3
GOLGA6L9
GPRASP3
GRAMD4
HES6
HNRNPC
HOMEZ
HOXD3
HSF2BP
HSPB1
IGKC
IKBIP
IKZF3
INSC
IQCB1
JUN
KATNBL1
KDM1A
KEAP1
KIAA0753
KLF1
KMT5B
KRT15
KRT16
KRT18
KRT27
KRT31
KRT34
KRT37
KRT38
KRT75
LDB2
LDOC1
LZTS2
MAGEA2
MAGEA2B
MAGEA6
MED4
MKRN3
MTNR1B
MTUS2
NAB2
NECAB2
NELFA
NME1
NONO
NR1H4
NR3C1
NUCB2
NUDT16L1
NUTM1
OGT
PACSIN3
PAICS
PBX4
PCBD1
PGR
PICK1
PIH1D1
PKNOX2
PLAGL2
PPM1J
PRDX1
PRMT6
PSTPIP1
RIF1
RORB
RPS29
SCARA5
SCHIP1
SCNM1
SERTAD3
SHISA6
SMUG1
SNF8
SPSB2
STH
STMN3
SYCE1L
TCP10L
THOC7
TLE5
TNIP2
TP53
TRIM27
TRIM54
TRIM72
USHBP1
USP54
VPS37B
WASHC1
YJU2B
YWHAG
ZC2HC1C
ZMAT5
ZMYND12
ZNF417
ZNF438
ZNF511
ZNF629
ZNF655
ZNF69
Entrez ID
2908
6602
HPRD ID
00679
03438
Ensembl ID
ENSG00000113580
ENSG00000066117
Uniprot IDs
E5KQF5
E5KQF6
F1D8N4
P04150
Q96GM5
PDB IDs
1M2Z
1NHZ
1P93
3BQD
3CLD
3E7C
3H52
3K22
3K23
4CSJ
4HN5
4HN6
4LSJ
4MDD
4P6W
4P6X
4UDC
4UDD
5CBX
5CBY
5CBZ
5CC1
5E69
5E6A
5E6B
5E6C
5E6D
5EMC
5EMP
5EMQ
5G3J
5G5W
5NFP
5NFT
5UC1
5UC3
5VA0
5VA7
6BQU
6CFN
6DXK
6EL6
6EL7
6EL9
6X6D
6X6E
6YMO
6YO8
6YOS
7KRJ
7KW7
7PRV
7PRW
7PRX
8A9G
8FFV
8FFW
8VKZ
6LTH
6LTJ
7VDV
7Y8R
Enriched GO Terms of Interacting Partners
?
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Regulation Of Primary Metabolic Process
Positive Regulation Of Biosynthetic Process
Nucleoplasm
Nucleus
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Chromatin
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Transcription Coactivator Activity
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA Binding
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Metabolic Process
Intracellular Receptor Signaling Pathway
Response To Lipid
Negative Regulation Of Biosynthetic Process
Chromatin Binding
Response To Hormone
Nuclear Receptor-mediated Signaling Pathway
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Nuclear Receptor Binding
Nuclear Glucocorticoid Receptor Binding
Intracellular Signal Transduction
Transcription Cis-regulatory Region Binding
Protein-containing Complex
Hormone-mediated Signaling Pathway
Transcription Regulator Complex
Enzyme Binding
Steroid Hormone Receptor Signaling Pathway
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Cellular Response To Hormone Stimulus
Protein Binding
Identical Protein Binding
Structural Constituent Of Skin Epidermis
Intermediate Filament Cytoskeleton Organization
Keratin Filament
Intermediate Filament-based Process
Nucleus
Intermediate Filament Organization
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Estrogen Response Element Binding
Supramolecular Fiber Organization
Cytoskeleton
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Primary Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Receptor Activity
DNA-binding Transcription Factor Activity
Intermediate Filament
Regulation Of Actin Nucleation
Regulation Of Nucleobase-containing Compound Metabolic Process
Developmental Process
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Structural Molecule Activity
Actin-based Cell Projection
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of MiRNA Transcription
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Sequence-specific DNA Binding
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Transcription Coactivator Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
Steroid Binding
SCAR Complex
Positive Regulation Of MiRNA Transcription
Cornified Envelope
Regulation Of MiRNA Metabolic Process
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Tertiary Branching Involved In Mammary Gland Duct Morphogenesis
Protein Kinase C Inhibitor Activity
Cytoskeleton Organization
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Tagcloud (Intersection)
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