NR3C1 and MDM2

  • Number of citations of the paper that reports this interaction (PMID 11562347)
  • 22
  • Data Source:
  • HPRD (in vivo)

NR3C1

MDM2

Gene Name nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) MDM2 proto-oncogene, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 135 interactors: ADA AR ARPC5 BAG1 CALM1 CALR CEBPA CEBPB CENPB CHD9 COPS6 CREB1 CREBBP DAP3 DAXX DCAF6 DDX54 ECD ETS1 ETS2 FKBP4 FTH1 FYN GNB1 GNB2 GNB2L1 GRIP1 HDAC6 HMGB1 HMGB2 HMOX2 HNRNPA1 HNRNPU HSP90AA1 HSPA1A HSPD1 IDE IFNGR2 JUN KAT5 KDM5A KPNA2 LCK LRIF1 MAFF MAPK1 MAPK15 MAPK8 MDM2 MED1 MED14 MED25 MSX2 NCL NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOR1 NCOR2 NEDD4L NFKB1 NFKB2 NR0B1 NR1H3 NR2E3 NR2F2 NR2F6 NR3C2 NR4A1 NRIP1 ONECUT1 OSGEP PBX1 PELP1 PIAS2 PML POLR1D POU1F1 POU2F1 POU2F2 PPARGC1A PRKACA PRKDC PRPF6 PSMC3IP PTGES3 PTMS RAD54L2 RAD9A RAF1 RAN RARA RBM14 RELA RNF14 RXRB SFN SLC25A4 SMAD3 SMARCA2 SMARCA4 SMARCB1 SMARCC1 SMARCD1 SMARCE1 SRA1 SRC STAT3 STAT5A STAT5B SUMO1 SUMO4 SVIL SYT1 TADA2A TBP TDG TGFB1I1 TMF1 TP53 TRIM24 TRIM28 TSG101 TXN UBB UBE2I UBE2L3 YWHAH ZBTB16 ZBTB20 ZBTB3 ZBTB9 ZNF496 185 interactors: ABL1 ADRB2 ADRBK1 AKT1 ANKRD17 APEX1 APP AR ARRB2 ATF3 ATF4 ATM ATP2A2 AURKA BAIAP2L1 BRINP1 BTRC CANX CASP2 CASP3 CCAR1 CCNG1 CDH1 CDKN2A CHEK2 CLSTN1 CLU COPS5 CREBBP CTBP2 CWC25 DAPK1 DAPK3 DAXX DHFR DLG4 DNAJB4 DYRK2 E2F1 EID1 EP300 ESR1 EZR FOXO1 G3BP2 GADD45A GCAT GLTSCR2 GNL3 GORAB GSK3B GTF2E1 GTF2E2 HDAC1 HIF1A HIPK2 HIST2H2BE HIST3H3 HLA-DMB HRSP12 HSP90B1 IGF1R IRF1 IRF2 JMY JUN JUND KAT2B KAT5 LMO7 MDM4 MED1 MKRN3 MS4A1 MTBP MYD88 MYDGF NACA NCL NOTCH1 NPM1 NR3C1 NUMB PAK6 PBX1 PDE4D PDIA3 PDLIM7 PGAM2 PHF7 PIAS1 PJA1 PKM PLK1 PML POLE POT1 PPIB PPM1D PSMA3 PSMC5 PSMD10 PSMD4 PSME3 PTK2 RAB8A RABL6 RAD23A RANBP1 RANBP2 RASSF1 RB1 RBM38 RCHY1 RNF10 RNF126 RNF8 RPL11 RPL26 RPL5 RPS23 RPS27A RPS3 RPS7 RRM2B RUVBL2 RYBP RYR2 S100A1 S100A2 S100A4 S100A6 S100B SDHC SENP3 SESN2 SET SETDB1 SHPK SMARCA2 SMARCA4 SMARCE1 SORBS2 SREK1 SRSF11 SUMO1 TAF1 TBP TCAP TERT TOP1 TP53 TP73 TPR TPT1 TRAF5 TRIM23 TRIM27 TRIM4 TRIM9 TSC22D3 TSG101 UBB UBE2A UBE2D1 UBE2D2 UBE2D3 UBE2E2 UBE2E3 UBE2G2 UBE2I UBE2K UBE2L3 UBE2M UBE2U UBE2Z UBE3A UBQLN4 UBTF USP2 USP7 WT1 XPC YY1AP1 ZNF133
Entrez ID 2908 4193
HPRD ID 00679 01272
Ensembl ID ENSG00000113580 ENSG00000135679
Uniprot IDs B7Z7I2 E5KQF5 E5KQF6 F1D8N4 P04150 A7UKX7 A7UKX8 A7UKX9 G3XA89 Q00987 Q96DS0
PDB IDs 1M2Z 1NHZ 1P93 3BQD 3CLD 3E7C 3H52 3K22 3K23 4HN5 4HN6 1RV1 1T4E 1T4F 1YCR 1Z1M 2AXI 2C6A 2C6B 2F1Y 2FOP 2GV2 2HDP 2LZG 2M86 2VJE 2VJF 3EQS 3G03 3IUX 3IWY 3JZK 3JZR 3JZS 3LBK 3LBL 3LNJ 3LNZ 3TJ2 3TPX 3TU1 3V3B 3VBG 3VZV 3W69 4DIJ 4ERE 4ERF 4HBM 4HFZ 4JV7 4JV9 4JVE 4JVR 4JWR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
2xglucocorticoid  2xgre  agonism  agonists  beas  bronchial  budesonide  cdkn1c  ciclesonide  combat  dexamethasone  dusp1  fluticasone  formoterol  furoate  glucocorticoid  glucocorticoids  gre  gsk9027  gw870086x  ikk2  phosphoinositide  propionate  reporter  rgs2  ru24858  suboptimal  tsc22d3  viii 
abundance  bound  cbp  coactivator  destabilizer  directed  e1a  endogenous  h1  implies  implying  interactions  intimately  naturally  normally  occurring  operate  overproducing  p300  p53  regard  serves  stability  stabilizing  steps  taken  translates  turnover  underscored 
Tagcloud (Difference) ?
2xglucocorticoid  2xgre  agonism  agonists  beas  bronchial  budesonide  cdkn1c  ciclesonide  combat  dexamethasone  dusp1  fluticasone  formoterol  furoate  glucocorticoid  glucocorticoids  gre  gsk9027  gw870086x  ikk2  phosphoinositide  propionate  reporter  rgs2  ru24858  suboptimal  tsc22d3  viii 
abundance  bound  cbp  coactivator  destabilizer  directed  e1a  endogenous  h1  implies  implying  interactions  intimately  naturally  normally  occurring  operate  overproducing  p300  p53  regard  serves  stability  stabilizing  steps  taken  translates  turnover  underscored 
Tagcloud (Intersection) ?