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MDM2 and CREBBP
Number of citations of the paper that reports this interaction (PubMedID
9809062
)
0
Data Source:
HPRD
(in vitro)
MDM2
CREBBP
Description
MDM2 proto-oncogene
CREB binding lysine acetyltransferase
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Postsynaptic Density
Nuclear Body
Transcription Repressor Complex
Endocytic Vesicle Membrane
Protein-containing Complex
Centriolar Satellite
Glutamatergic Synapse
Histone Acetyltransferase Complex
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Cytosol
Nuclear Body
Molecular Function
P53 Binding
Ubiquitin-protein Transferase Activity
Protein Binding
5S RRNA Binding
Zinc Ion Binding
Transferase Activity
Ligase Activity
SUMO Transferase Activity
Enzyme Binding
Protein Domain Specific Binding
Ubiquitin Protein Ligase Binding
Receptor Serine/threonine Kinase Binding
Identical Protein Binding
Peroxisome Proliferator Activated Receptor Binding
Ribonucleoprotein Complex Binding
Ubiquitin Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
NEDD8 Ligase Activity
Disordered Domain Specific Binding
Transcription Coactivator Binding
P53 Binding
Chromatin Binding
Damaged DNA Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
Transcription Corepressor Activity
Histone Acetyltransferase Activity
Protein Binding
Zinc Ion Binding
Acetyltransferase Activity
Transferase Activity
Acyltransferase Activity
Chromatin DNA Binding
MRF Binding
Histone H3K18 Acetyltransferase Activity
Histone H3K27 Acetyltransferase Activity
Metal Ion Binding
Tau Protein Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Protein-lysine-acetyltransferase Activity
Peptide Lactyltransferase (CoA-dependent) Activity
DNA-binding Transcription Factor Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Protein Polyubiquitination
Blood Vessel Development
Blood Vessel Remodeling
Regulation Of Heart Rate
Heart Valve Development
Atrioventricular Valve Morphogenesis
Endocardial Cushion Morphogenesis
Ventricular Septum Development
Atrial Septum Development
Ubiquitin-dependent Protein Catabolic Process
Apoptotic Process
Traversing Start Control Point Of Mitotic Cell Cycle
Heart Development
Positive Regulation Of Cell Population Proliferation
Response To Xenobiotic Stimulus
Response To Toxic Substance
Response To Iron Ion
Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Protein Processing
Negative Regulation Of Neuron Projection Development
Protein Ubiquitination
Protein Sumoylation
DNA Damage Response, Signal Transduction By P53 Class Mediator
Protein Destabilization
Response To Magnesium Ion
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Localization To Nucleus
Regulation Of Protein Catabolic Process
Response To Cocaine
Negative Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Protein-containing Complex Organization
Establishment Of Protein Localization
Response To Ether
Positive Regulation Of Cell Cycle
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Mitotic Cell Cycle
Response To Antibiotic
Positive Regulation Of Protein Export From Nucleus
Response To Steroid Hormone
Positive Regulation Of Muscle Cell Differentiation
Proteolysis Involved In Protein Catabolic Process
Regulation Of Cell Cycle
Protein Autoubiquitination
Cardiac Septum Morphogenesis
Protein-containing Complex Assembly
Regulation Of Biological Quality
Cellular Response To Hydrogen Peroxide
Cellular Response To Antibiotic
Cellular Response To Vitamin B1
Cellular Response To Alkaloid
Cellular Response To Growth Factor Stimulus
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Estrogen Stimulus
Cellular Response To Hypoxia
Cellular Response To Gamma Radiation
Cellular Response To UV-C
Signal Transduction By P53 Class Mediator
Fibroblast Activation
Cellular Response To Actinomycin D
Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission
Negative Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Response To Formaldehyde
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration
Amyloid Fibril Formation
Response To Water-immersion Restraint Stress
Negative Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Transcription By RNA Polymerase II
Double-strand Break Repair Via Homologous Recombination
Response To Hypoxia
Stimulatory C-type Lectin Receptor Signaling Pathway
Chromatin Remodeling
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Protein Acetylation
Signal Transduction
Canonical NF-kappaB Signal Transduction
Regulation Of Smoothened Signaling Pathway
Negative Regulation Of Transcription By RNA Polymerase I
N-terminal Peptidyl-lysine Acetylation
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Protein Destabilization
Cellular Response To Nutrient Levels
Cellular Response To UV
Homeostatic Process
Embryonic Digit Morphogenesis
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Rhythmic Process
Protein Stabilization
Protein-containing Complex Assembly
Protein K48-linked Deubiquitination
Energy Homeostasis
Regulation Of Cellular Response To Heat
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways
AKT phosphorylates targets in the cytosol
Oxidative Stress Induced Senescence
Oncogene Induced Senescence
SUMOylation of transcription factors
SUMOylation of ubiquitinylation proteins
Trafficking of AMPA receptors
Constitutive Signaling by AKT1 E17K in Cancer
Ub-specific processing proteases
Regulation of TP53 Activity through Phosphorylation
Regulation of TP53 Degradation
Regulation of TP53 Activity through Methylation
Stabilization of p53
Regulation of RUNX3 expression and activity
Signaling by ALK fusions and activated point mutants
Degradation of CDH1
NPAS4 regulates expression of target genes
Regulation of gene expression by Hypoxia-inducible Factor
BMAL1:CLOCK,NPAS2 activates circadian expression
Pre-NOTCH Transcription and Translation
Pre-NOTCH Transcription and Translation
PPARA activates gene expression
PPARA activates gene expression
Formation of the beta-catenin:TCF transactivating complex
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
NOTCH1 Intracellular Domain Regulates Transcription
NOTCH1 Intracellular Domain Regulates Transcription
Transcriptional activation of mitochondrial biogenesis
Activation of gene expression by SREBF (SREBP)
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
HATs acetylate histones
Attenuation phase
Notch-HLH transcription pathway
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
SUMOylation of transcription cofactors
Regulation of lipid metabolism by PPARalpha
Activation of anterior HOX genes in hindbrain development during early embryogenesis
CD209 (DC-SIGN) signaling
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Activation of the TFAP2 (AP-2) family of transcription factors
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
RUNX3 regulates NOTCH signaling
RUNX3 regulates NOTCH signaling
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH4 Intracellular Domain Regulates Transcription
Estrogen-dependent gene expression
TRAF3-dependent IRF activation pathway
TRAF6 mediated IRF7 activation
FOXO-mediated transcription of cell death genes
Regulation of FOXO transcriptional activity by acetylation
Regulation of FOXO transcriptional activity by acetylation
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Cytoprotection by HMOX1
Heme signaling
Nuclear events mediated by NFE2L2
NPAS4 regulates expression of target genes
Formation of paraxial mesoderm
NFE2L2 regulating inflammation associated genes
NFE2L2 regulating anti-oxidant/detoxification enzymes
NFE2L2 regulates pentose phosphate pathway genes
NFE2L2 regulating tumorigenic genes
NFE2L2 regulating MDR associated enzymes
NFE2L2 regulating ER-stress associated genes
Regulation of NFE2L2 gene expression
Regulation of NFE2L2 gene expression
Zygotic genome activation (ZGA)
Evasion by RSV of host interferon responses
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Transcriptional and post-translational regulation of MITF-M expression and activity
Transcriptional and post-translational regulation of MITF-M expression and activity
Regulation of PD-L1(CD274) transcription
Expression of BMAL (ARNTL), CLOCK, and NPAS2
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression
Drugs
Zinc
Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone
Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Colforsin
9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE
Diseases
Penile cancer
Alveolar rhabdomyosarcoma
Choriocarcinoma
Osteosarcoma
Glioma
Rubinstein-Taybi syndrome
GWAS
Pneumoconiosis in silica exposure (
24986923
)
Red blood cell count (
32888494
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Heel bone mineral density (
30598549
)
Metabolite levels (HVA/5-HIAA ratio) (
23319000
)
Neutrophil count (
32888494
)
Nonsyndromic cleft lip with cleft palate (
28232668
)
Nonsyndromic cleft lip with or without cleft palate (
25775280
)
Obesity-related traits (
23251661
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
QT interval (
24952745
)
QT interval (drug interaction) (
23459443
)
White blood cell count (
32888494
)
Interacting Genes
271 interacting genes:
ABL1
ABL2
ADRB2
AKAP5
AKT1
ANKRD17
APEX1
APOB
APP
AR
ARRB1
ARRB2
ATF3
ATF4
ATM
ATP2A2
ATRX
AURKA
BAIAP2L1
BRINP1
BTK
BTRC
CANX
CASP2
CASP3
CCAR1
CCDC3
CCNG1
CDC34
CDKN2A
CHEK2
CLSTN1
CLU
COPS5
CREBBP
CSNK2A1
CSNK2A2
CSNK2B
CTBP2
CWC25
DAPK1
DAPK3
DAXX
DDX24
DDX42
DHFR
DLG4
DNAJB4
DYRK2
EGLN3
EID1
EP300
ESR1
EZR
F3
FBXO31
FHL2
FKBP1A
FOS
FOXO1
FOXO3
FOXP3
G3BP2
GADD45A
GCAT
GLIS2
GNL3
GORAB
GRK2
GSK3B
GTF2E2
GYS2
H2BC21
H3-4
HCK
HDAC1
HEY1
HIF1A
HIPK2
HLA-DMB
HMGA2
HMGN1
HNRNPK
HSP90B1
IER3
IGF1R
IL33
IRF1
IRF2
JMY
JUN
JUND
KAT2B
KAT5
KIAA1671
KPNA1
LMO7
MAGEA2
MAGEC2
MAP1LC3A
MAP2
MAPKAPK2
MAPT
MDM4
MED1
MKRN3
MS4A1
MTBP
MYC
MYD88
MYDGF
NACA
NAT10
NCL
NDUFS1
NGFR
NOLC1
NOTCH1
NPIPB3
NPM1
NR1I2
NR3C1
NRON
NUCKS1
NUMB
OVOL2
PADI4
PAK6
PBX1
PBXIP1
PDCD1
PDE4D
PDIA3
PDLIM7
PDS5A
PGAM2
PHF7
PHLDB3
PIAS1
PJA1
PKM
PLK1
PML
POLE
POT1
PPIB
PPM1D
PPP1R10
PRDM2
PRKN
PSMA3
PSMC5
PSMD10
PSMD4
PSME3
PTK2
RAB8A
RAD23A
RALY
RANBP1
RANBP2
RARA
RASSF1
RB1
RBBP6
RBM10
RBM38
RESF1
RIDA
RLIM
RNF10
RNF115
RNF126
RNF8
RPL11
RPL22
RPL26
RPL36A
RPL4
RPL5
RPS23
RPS3
RPS5
RRM2B
RRP1
RSL1D1
RUVBL2
RYBP
RYR2
S100A1
S100A2
S100A4
S100A6
S100B
SDHC
SESN2
SET
SETD7
SETDB1
SHPK
SIRT2
SIRT3
SMARCA2
SMARCA4
SMARCE1
SMG7
SNCA
SORBS2
SRC
SREK1
SRSF11
SUMO1
TAF1
TBP
TCAP
TFIP11
TOP1
TP53
TP53I3
TP53RK
TP73
TPR
TPT1
TRAF5
TRIB3
TRIM13
TRIM23
TRIM27
TRIM4
TRIM9
TSG101
UBB
UBC
UBE2A
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2G2
UBE2H
UBE2I
UBE2J2
UBE2K
UBE2L3
UBE2N
UBE2O
UBE2Q1
UBE2Q2
UBE2R2
UBE2S
UBE2U
UBE2Z
UBE3A
UBQLN4
UBTF
USP15
USP2
USP7
VCP
VEGFA
WRN
WT1
XBP1
XIAP
XPC
YY1AP1
ZNF133
ZNF420
364 interacting genes:
ACSS1
ACTA2
ACTB
ACVR1
AFP
AIRE
AKT1
ALX1
ANAPC5
ANAPC7
ANKS1A
ANKS1B
ANXA7
AP1B1
APC
APP
AR
ATF1
ATF3
ATF4
ATF7IP
ATRX
BAG5
BCL3
BCL6
BRCA1
BRIP1
CALCOCO1
CAMK4
CAMSAP2
CARM1
CASP8AP2
CBX4
CDC25B
CDH2
CDK5RAP3
CDX2
CEBPA
CEBPB
CEBPD
CEP290
CHAF1A
CHD3
CHRDL1
CHUK
CIITA
CITED1
CITED2
CLASP2
CNOT3
CNTRL
CPAP
CPSF4
CREB1
CREM
CRX
CSK
CSNK2A1
CSNK2A2
CTBP1
CTNNB1
CUX1
DACH1
DAXX
DDX17
DDX5
DEK
E2F1
E2F5
EBF1
EEF1A1
EEF2
EGR1
EID1
EID3
EIF2B1
EIF3D
EIF4G2
ELF3
ELK1
EP300
EPG5
ESR1
ETS1
ETS2
EWSR1
EXOC5
FAF1
FBXL19
FBXO38
FGFR1
FHL2
FOXH1
FOXM1
FOXO1
FOXO3
FOXO4
FUS
GAA
GABPA
GAK
GATA1
GATAD2A
GCM1
GLI3
GMEB1
GMEB2
GPR161
GRIA3
GSTO2
GTF2B
H2AC4
H2BC21
H2BC3
H3-3A
H3-4
H3C1
H4C16
HBP1
HCK
HDAC1
HDAC3
HEXA
HIF1A
HIPK1
HIPK2
HIPK3
HIVEP1
HIVEP2
HLF
HMG20A
HMGA1
HMGB1
HMGB2
HMGXB4
HNF1A
HNF1B
HNF4A
HNRNPL
HOXA10
HOXA11
HOXA9
HOXB1
HOXB2
HOXB3
HOXB4
HOXB6
HOXB7
HOXB9
HOXD10
HOXD12
HOXD13
HOXD4
HSF1
HTT
HUWE1
IKBKG
IQGAP1
IRF1
IRF3
IRF5
IRF7
JDP2
JUN
KAT2A
KAT2B
KAT5
KAT6A
KDM2B
KDM3B
KDM6A
KDM6B
KHDRBS1
KIF5A
KISS1
KLF1
KLF13
KLF4
KLF5
KMT2A
KMT2D
KPNA2
KPNA6
LATS1
LDLR
LIG4
LYN
MAF
MAFG
MAML1
MAML2
MAP1B
MAP3K5
MAPK1
MAPK10
MAPK3
MAPT
MARK2
MBD2
MDC1
MDM2
MECOM
MED25
MGMT
MIER1
MKNK1
MOB1A
MSH2
MSH6
MSX1
MYB
MYBL1
MYBL2
MYC
MYO1E
MYOD1
N4BP2
NAP1L1
NCOA1
NCOA2
NCOA3
NCOA6
NEUROG1
NFATC2
NFATC4
NFE2
NFE2L2
NFIA
NFIC
NKX2-1
NLK
NPAS2
NPAT
NR3C1
NR5A1
NUP98
OGT
ONECUT1
PAPPA
PAX5
PBX1
PCMT1
PCNA
PELP1
PHLDA1
PHOX2A
PIAS1
PIAS2
PIAS3
PLAGL1
PML
POLR2A
POU1F1
POU2F3
PPARGC1A
PPP1R8
PPP2R2A
PRKCD
PRKCZ
PRLR
PROX1
PSME3
PTMA
PTPRF
RAD23A
RAD50
RBBP4
RBBP7
RBCK1
RBM24
RBM5
RELA
RFK
RNF111
RNF7
RPL3
RPL35
RPS20
RPS6KA1
RPS6KA3
RPS6KA5
RXRG
SEMA3B
SEPTIN3
SERTAD1
SERTAD2
SERTAD3
SETDB1
SH3GL1
SHCBP1
SLC1A4
SMAD1
SMAD2
SMAD3
SMAD4
SNAI1
SNAI2
SNAPC5
SND1
SNIP1
SNRNP200
SOS2
SOX9
SP100
SPI1
SPIB
SPTAN1
SRCAP
SREBF1
SREBF2
SRF
SS18L1
STAT1
STAT2
STAT3
STAT4
STAT6
SUMO1
SUV39H1
SYT1
TACC2
TAF6L
TCF12
TCF3
TDG
TFDP1
TGS1
THRA
TIAL1
TIAM1
TOPORS
TP53
TP53BP2
TP73
TRERF1
TRIM24
TRIP10
TRIP4
TSPYL2
TUBB
UBE2D1
UBE2I
UBTF
UIMC1
VAT1L
VDR
WAS
WDR77
WT1
XAF1
XRCC6
YTHDF2
YWHAH
YY1
ZBTB17
ZBTB2
ZCCHC7
ZHX1
ZMYM2
ZMYM5
ZNF106
ZNF451
ZNF639
ZNFX1
Entrez ID
4193
1387
HPRD ID
01272
02534
Ensembl ID
ENSG00000135679
ENSG00000005339
Uniprot IDs
A0A0A8KB75
A7UKX7
A7UKX8
A7UKX9
G3XA89
Q00987
Q96DS0
Q92793
PDB IDs
1RV1
1T4E
1T4F
1YCR
1Z1M
2AXI
2C6A
2C6B
2F1Y
2FOP
2GV2
2HDP
2LZG
2M86
2MPS
2RUH
2VJE
2VJF
3EQS
3G03
3IUX
3IWY
3JZK
3JZR
3JZS
3LBK
3LBL
3LNJ
3LNZ
3MQS
3TJ2
3TPX
3TU1
3V3B
3VBG
3VZV
3W69
4DIJ
4ERE
4ERF
4HBM
4HFZ
4HG7
4JV7
4JV9
4JVE
4JVR
4JWR
4MDN
4MDQ
4OAS
4OBA
4OCC
4ODE
4ODF
4OGN
4OGT
4OGV
4OQ3
4QO4
4QOC
4UD7
4UE1
4UMN
4WT2
4XXB
4ZFI
4ZGK
4ZYC
4ZYF
4ZYI
5AFG
5C5A
5HMH
5HMI
5HMK
5J7F
5J7G
5LAV
5LAW
5LAY
5LAZ
5LN2
5MNJ
5OAI
5OC8
5SWK
5TRF
5UMM
5VK0
5WTS
5XXK
5Z02
5ZXF
6AAW
6GGN
6H22
6HFA
6I29
6I3S
6IM9
6KZU
6Q96
6Q9H
6Q9L
6Q9O
6SQO
6T2D
6T2E
6T2F
6Y4Q
6YR6
7AD0
7AI0
7AI1
7AYE
7BIR
7BIT
7BIV
7BJ0
7BJ6
7BMG
7KJM
7NA1
7NA2
7NA3
7NA4
7NUS
7QDQ
8AEU
8BGU
8EI9
8EIA
8EIB
8EIC
8F0Z
8F10
8F12
8F13
8GCG
8J81
8P0D
8PWC
9GFC
1JSP
1LIQ
1RDT
1WO3
1WO4
1WO5
1WO6
1WO7
1ZOQ
2D82
2KJE
2KWF
2L84
2L85
2LXS
2LXT
2N1A
2RNY
3DWY
3P1C
3P1D
3P1E
3P1F
3SVH
4A9K
4N3W
4N4F
4NR4
4NR5
4NR6
4NR7
4NYV
4NYW
4NYX
4OUF
4TQN
4TS8
4WHU
4YK0
5CGP
5DBM
5EIC
5ENG
5EP7
5GH9
5H85
5I83
5I86
5I89
5I8B
5I8G
5J0D
5JEM
5KTU
5KTW
5KTX
5LPJ
5LPL
5MME
5MMG
5MPK
5MPN
5MPZ
5MQE
5MQG
5MQK
5NLK
5NRW
5NU3
5OWK
5SVH
5TB6
5W0E
5W0F
5W0L
5W0Q
5XXH
6ALB
6ALC
6AXQ
6AY3
6AY5
6DMK
6ES5
6ES6
6ES7
6FQO
6FQT
6FQU
6FR0
6FRF
6LQX
6M64
6QST
6SQE
6SQF
6SQM
6SXX
6YIJ
6YIK
6YIL
6YIM
7CO1
7EVJ
7JFL
7JFM
7JUO
7KPY
7RLE
7TB3
7TBH
7UGE
7UGL
7WX2
7XH6
7XHE
7XI0
7XIJ
7XM7
7XNE
7XNG
8FUP
8FV2
8FXA
8FXE
8FXN
8FXO
8G6T
8GA2
8HAL
8HAM
8HAN
9J6O
9JUU
9JUY
Enriched GO Terms of Interacting Partners
?
Nucleus
Nucleoplasm
Macromolecule Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Regulation Of Primary Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Cellular Response To Stress
Ubiquitin Conjugating Enzyme Activity
Positive Regulation Of Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of RNA Metabolic Process
Protein Modification Process
Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Protein Metabolic Process
Regulation Of Programmed Cell Death
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Apoptotic Process
Post-translational Protein Modification
Protein Modification By Small Protein Conjugation
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Protein Metabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of RNA Metabolic Process
Protein Ubiquitination
Regulation Of Signal Transduction
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of DNA-templated Transcription
Proteolysis Involved In Protein Catabolic Process
Positive Regulation Of RNA Biosynthetic Process
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Macromolecule Biosynthetic Process
Macromolecule Catabolic Process
DNA Damage Response
Positive Regulation Of Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Signal Transduction By P53 Class Mediator
Cytosol
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
Regulation Of Signaling
Regulation Of Cell Communication
Response To Stress
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of RNA Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleoplasm
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Macromolecule Biosynthetic Process
Nucleus
Regulation Of Macromolecule Metabolic Process
Regulation Of Gene Expression
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Biosynthetic Process
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Chromatin
DNA Binding
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
DNA-binding Transcription Factor Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Sequence-specific DNA Binding
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Metabolic Process
Sequence-specific Double-stranded DNA Binding
Transcription Cis-regulatory Region Binding
Transcription Regulator Complex
Chromatin Binding
DNA-templated Transcription
Regulation Of Developmental Process
Cellular Developmental Process
Regulation Of Cell Differentiation
RNA Polymerase II Transcription Regulator Complex
Cell Differentiation
DNA-binding Transcription Factor Binding
Developmental Process
Chromatin Organization
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