LSM3 and TCL1A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LSM3	TCL1A
Gene Name		LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	T-cell leukemia/lymphoma 1A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Catalytic Step 2 Spliceosome	Endoplasmic Reticulum Cell Cortex Pronucleus
	Molecular Function	Protein Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Splicing, Via Spliceosome MRNA Processing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	Multicellular Organismal Development Stem Cell Maintenance
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS			Adverse response to aromatase inhibitors ( 21172079 20876420)
Protein-Protein Interactions		28 interactors: CEP95 CLNS1A DLX4 EEF1A1 GDF9 GSTA1 KEAP1 LSM1 LSM10 LSM2 LSM5 LSM6 LSM7 LSM8 SF3B2 SMN1 SNRPD1 SNRPD3 SNRPE SNRPG TCL1A THOC5 UTP14A WDR77 WDR83 XPC XRN2 YBX1	21 interactors: AKT1 AKT2 AKT3 ALS2CR12 ATM CADPS CALCOCO2 CARD9 CEP55 DNMT3A GOLGA2 HIST3H2A LSM3 PRTFDC1 TCF4 TP53BP2 TRAF1 TTC33 TXLNA TXLNB WDR47
Entrez ID		27258	8115
HPRD ID		06283	01744
Ensembl ID			ENSG00000100721
Uniprot IDs		P62310	P56279
PDB IDs			1JSG
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing MRNA Metabolic Process RNA Processing RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Spliceosomal SnRNP Assembly Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Ribonucleoprotein Complex Assembly NcRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay DNA-templated Transcription, Termination RNA Catabolic Process Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Aromatic Compound Catabolic Process Nuclear-transcribed MRNA Catabolic Process Spliceosomal Complex Assembly MRNA Catabolic Process MRNA 3'-end Processing Cellular Macromolecule Catabolic Process Cellular Macromolecular Complex Assembly RNA 3'-end Processing Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Process Catabolic Process Maturation Of SSU-rRNA Transcription, DNA-templated RNA Biosynthetic Process Ribosomal Small Subunit Biogenesis Oocyte Growth Nucleotide-excision Repair, DNA Damage Recognition Cellular Component Assembly Regulation Of Stem Cell Division Negative Regulation Of DNA Damage Checkpoint Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Progesterone Secretion Proteasomal Ubiquitin-independent Protein Catabolic Process CRD-mediated MRNA Stabilization See more	Positive Regulation Of Glucose Metabolic Process Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Glycogen Metabolic Process Polysaccharide Metabolic Process Peripheral Nervous System Myelin Maintenance Positive Regulation Of Glycogen Biosynthetic Process Glial Cell Development Regulation Of Glucose Metabolic Process Regulation Of Fatty Acid Beta-oxidation Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Energy Reserve Metabolic Process Negative Regulation Of Lipid Transport Glucose Metabolic Process Glycogen Biosynthetic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Response To Radiation Glial Cell Differentiation Regulation Of Fatty Acid Transport Cell Cycle Myelination In Peripheral Nervous System Positive Regulation Of Glucose Import Intrinsic Apoptotic Signaling Pathway Cellular Polysaccharide Biosynthetic Process Regulation Of Glycogen Metabolic Process Schwann Cell Development Positive Regulation Of Glucose Transport Regulation Of Extrinsic Apoptotic Signaling Pathway Polysaccharide Biosynthetic Process Regulation Of Cell Cycle Hexose Metabolic Process Apoptotic Process Negative Regulation Of Ion Transmembrane Transport Positive Regulation Of Intracellular Transport Cellular Carbohydrate Metabolic Process Regulation Of Myelination Gliogenesis Programmed Cell Death Schwann Cell Differentiation Monosaccharide Metabolic Process Negative Regulation Of Transmembrane Transport Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Glycogen Cell Differentiation Involved In Embryonic Placenta Development Cell Death Regulation Of Glucose Import Death Regulation Of Lipid Catabolic Process Positive Regulation Of Lipid Biosynthetic Process See more
Tagcloud ?			14q atm coexpression cutaneous cutis epidermotropism gains immunophenotype infiltrates institution integral inversion involvement irregular karyotype lactate lymphoid manifestations papules periadnexal perivascular pll plls prolymphocytic purpura rash rearrangement sized ulcers
Tagcloud (Difference) ?			14q atm coexpression cutaneous cutis epidermotropism gains immunophenotype infiltrates institution integral inversion involvement irregular karyotype lactate lymphoid manifestations papules periadnexal perivascular pll plls prolymphocytic purpura rash rearrangement sized ulcers
Tagcloud (Intersection) ?