LSM3 and CEP95

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		LSM3	CEP95
Gene Name		LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	centrosomal protein 95kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Catalytic Step 2 Spliceosome	Spindle Pole Cytoplasm Centrosome
	Molecular Function	Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Splicing, Via Spliceosome MRNA Processing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: CEP95 CLNS1A DLX4 EEF1A1 GDF9 GSTA1 KEAP1 LSM1 LSM10 LSM2 LSM5 LSM6 LSM7 LSM8 SF3B2 SMN1 SNRPD1 SNRPD3 SNRPE SNRPG TCL1A THOC5 UTP14A WDR77 WDR83 XPC XRN2 YBX1	6 interactors: FAM9B LSM3 MTUS2 SPERT YWHAE YWHAG
Entrez ID		27258	90799
HPRD ID		06283	11279
Ensembl ID			ENSG00000258890
Uniprot IDs		P62310	B4DMD2 Q96GE4
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing MRNA Metabolic Process RNA Processing RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Spliceosomal SnRNP Assembly Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Ribonucleoprotein Complex Assembly NcRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay DNA-templated Transcription, Termination RNA Catabolic Process Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Aromatic Compound Catabolic Process Nuclear-transcribed MRNA Catabolic Process Spliceosomal Complex Assembly MRNA Catabolic Process MRNA 3'-end Processing Cellular Macromolecule Catabolic Process Cellular Macromolecular Complex Assembly RNA 3'-end Processing Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Process Catabolic Process Maturation Of SSU-rRNA Transcription, DNA-templated RNA Biosynthetic Process Ribosomal Small Subunit Biogenesis Oocyte Growth Nucleotide-excision Repair, DNA Damage Recognition Cellular Component Assembly Regulation Of Stem Cell Division Negative Regulation Of DNA Damage Checkpoint Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Progesterone Secretion Proteasomal Ubiquitin-independent Protein Catabolic Process CRD-mediated MRNA Stabilization	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization G2/M Transition Of Mitotic Cell Cycle Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Peptidyl-serine Dephosphorylation Regulation Of Heart Rate By Hormone Positive Regulation Of Intracellular Transport Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Apoptotic Signaling Pathway Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Organelle Organization Protein Targeting Regulation Of Intracellular Transport Regulation Of Heart Rate By Chemical Signal Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Membrane Repolarization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Establishment Of Protein Localization Mitotic Cell Cycle Process Regulation Of Membrane Repolarization Regulation Of Heart Rate By Cardiac Conduction Positive Regulation Of Transport Mitotic Cell Cycle Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Regulation Of Protein Localization Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Potassium Ion Transmembrane Transporter Activity Hippo Signaling Regulation Of Cellular Response To Heat Membrane Organization Negative Regulation Of Protein Metabolic Process Intracellular Protein Transport Regulation Of Organelle Organization Cardiac Muscle Cell Action Potential Substantia Nigra Development Apoptotic Process Regulation Of Potassium Ion Transmembrane Transport Programmed Cell Death Regulation Of Cellular Localization Cell Cycle Process Cell Death
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