EXOC1 and TRAF3IP1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		EXOC1	TRAF3IP1
Gene Name		exocyst complex component 1	TNF receptor-associated factor 3 interacting protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Cytosol Plasma Membrane Membrane	Centrosome Cilium Axoneme Intraciliary Transport Particle B Ciliary Basal Body Primary Cilium Ciliary Tip
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding
	Biological Process	Exocytosis Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization	Organelle Organization Neural Tube Patterning Embryonic Camera-type Eye Development Negative Regulation Of Interferon-beta Production Embryonic Heart Tube Development Post-anal Tail Morphogenesis Intraciliary Transport Cilium Assembly Embryonic Digit Morphogenesis Negative Regulation Of Defense Response To Virus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing	Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS		Cervical cancer ( 23817570)	Iris characteristics ( 21835309)
Protein-Protein Interactions		28 interactors: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST GOLGA4 KANSL1 KDM1A KIAA0226 KIAA1551 KIF5A LUC7L2 MACF1 NUF2 RALA RB1CC1 SFR1 SH3BP5 SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO	27 interactors: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT MACF1 OLFM1 SFR1 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 WAC
Entrez ID		55763	26146
HPRD ID		07615	09571
Ensembl ID		ENSG00000090989	ENSG00000204104
Uniprot IDs		Q9NV70	Q8TDR0
PDB IDs			2EQO
Enriched GO Terms of Interacting Partners?		Golgi To Plasma Membrane Transport Movement Of Cell Or Subcellular Component Regulation Of Cellular Component Organization Locomotion Nervous System Development Post-Golgi Vesicle-mediated Transport Microtubule-based Process Regulation Of Cell Projection Organization Generation Of Neurons Regulation Of Autophagy TOR Signaling Organelle Organization Golgi To Plasma Membrane Protein Transport Neurogenesis Regulation Of Cell Size Regulation Of Cellular Component Size Chemotaxis Intracellular Signal Transduction Cellular Component Assembly Regulation Of Neuron Projection Development Vesicle-mediated Transport Autophagy Cellular Localization Axon Guidance Regulation Of Neurogenesis Positive Regulation Of Axon Extension Autophagic Vacuole Assembly Establishment Of Localization In Cell Regulation Of Primitive Erythrocyte Differentiation Lamellipodium Assembly Involved In Ameboidal Cell Migration Lamellipodium Assembly Microtubule Cytoskeleton Organization Cell Projection Organization Cell Communication Lamellipodium Organization Positive Regulation Of Neural Precursor Cell Proliferation Macroautophagy Cell Projection Morphogenesis Regulation Of Cell Development Extension Of A Leading Process Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Negative Regulation Of SNARE Complex Assembly Cell Part Morphogenesis Cerebral Cortex Radially Oriented Cell Migration Axonogenesis Regulation Of Axon Extension Regulation Of Neuron Differentiation Regulation Of Organelle Organization Cell Cycle Response To External Stimulus Golgi Vesicle Transport	Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Cell Cycle Process Golgi To Plasma Membrane Protein Transport Meiotic Chromosome Condensation Cell Cycle Golgi Vesicle Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stress Generation Of Neurons TRIF-dependent Toll-like Receptor Signaling Pathway Neurogenesis Organelle Organization MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Signaling Cell Communication Mitotic Sister Chromatid Segregation Cell Division Establishment Of Protein Localization To Plasma Membrane Regulation Of Neurogenesis Toll-like Receptor 4 Signaling Pathway Nervous System Development Negative Regulation Of Cell Cycle Vesicle-mediated Transport Sister Chromatid Segregation Movement Of Cell Or Subcellular Component Cellular Localization Mitochondrial Calcium Ion Homeostasis Regulation Of Cell Differentiation Toll-like Receptor Signaling Pathway Membrane Organization Regulation Of Cell Development Regulation Of Neuron Differentiation Kinetochore Organization Mitotic Nuclear Division Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Protein Metabolic Process Mitotic Chromosome Condensation Pattern Recognition Receptor Signaling Pathway Regulation Of Cell Cycle Innate Immune Response-activating Signal Transduction Cellular Response To Stimulus Response To Stimulus Activation Of Innate Immune Response Signal Transduction Cell Differentiation Protein Localization To Plasma Membrane DNA Damage Checkpoint Regulation Of Neuron Projection Development
Tagcloud ?			13r1 arches chlamydomonas cilia ciliary ciliogenesis cilium connections cytoskeletal disc1 dyf elipsa enlarged evolutionarily hedgehog homologs ift54 localizes microtubules mipt3 patterning pharyngeal polydactyly raises sequestration stat6 tnfr ventral
Tagcloud (Difference) ?			13r1 arches chlamydomonas cilia ciliary ciliogenesis cilium connections cytoskeletal disc1 dyf elipsa enlarged evolutionarily hedgehog homologs ift54 localizes microtubules mipt3 patterning pharyngeal polydactyly raises sequestration stat6 tnfr ventral
Tagcloud (Intersection) ?