EXOC1 and CEP295

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		EXOC1	CEP295
Gene Name		exocyst complex component 1	centrosomal protein 295kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Cytosol Plasma Membrane Membrane	Cytoplasm Centrosome Centriole Cytoskeleton
	Molecular Function	Protein Binding
	Biological Process	Exocytosis Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization	Positive Regulation Of Organelle Assembly
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Cervical cancer ( 23817570)
Protein-Protein Interactions		28 interactors: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST GOLGA4 KANSL1 KDM1A KIAA0226 KIAA1551 KIF5A LUC7L2 MACF1 NUF2 RALA RB1CC1 SFR1 SH3BP5 SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO	1 interactors: EXOC1
Entrez ID		55763	85459
HPRD ID		07615	11159
Ensembl ID		ENSG00000090989	ENSG00000166004
Uniprot IDs		Q9NV70	Q9C0D2
PDB IDs
Enriched GO Terms of Interacting Partners?		Golgi To Plasma Membrane Transport Movement Of Cell Or Subcellular Component Regulation Of Cellular Component Organization Locomotion Nervous System Development Post-Golgi Vesicle-mediated Transport Microtubule-based Process Regulation Of Cell Projection Organization Generation Of Neurons Regulation Of Autophagy TOR Signaling Organelle Organization Golgi To Plasma Membrane Protein Transport Neurogenesis Regulation Of Cell Size Regulation Of Cellular Component Size Chemotaxis Intracellular Signal Transduction Cellular Component Assembly Regulation Of Neuron Projection Development Vesicle-mediated Transport Autophagy Cellular Localization Axon Guidance Regulation Of Neurogenesis Positive Regulation Of Axon Extension Autophagic Vacuole Assembly Establishment Of Localization In Cell Regulation Of Primitive Erythrocyte Differentiation Lamellipodium Assembly Involved In Ameboidal Cell Migration Lamellipodium Assembly Microtubule Cytoskeleton Organization Cell Projection Organization Cell Communication Lamellipodium Organization Positive Regulation Of Neural Precursor Cell Proliferation Macroautophagy Cell Projection Morphogenesis Regulation Of Cell Development Extension Of A Leading Process Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Negative Regulation Of SNARE Complex Assembly Cell Part Morphogenesis Cerebral Cortex Radially Oriented Cell Migration Axonogenesis Regulation Of Axon Extension Regulation Of Neuron Differentiation Regulation Of Organelle Organization Cell Cycle Response To External Stimulus Golgi Vesicle Transport
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