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EXOC1 and SH3BP5
Number of citations of the paper that reports this interaction (PMID
17043677
)
96
Data Source:
BioGRID
(two hybrid)
EXOC1
SH3BP5
Gene Name
exocyst complex component 1
SH3-domain binding protein 5 (BTK-associated)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Exocyst
Cytosol
Plasma Membrane
Membrane
Cytoplasm
Mitochondrion
Molecular Function
Protein Binding
Protein Kinase Inhibitor Activity
Protein Binding
SH3 Domain Binding
Biological Process
Exocytosis
Organelle Organization
Protein Transport
Cellular Protein Metabolic Process
Membrane Organization
Negative Regulation Of Protein Kinase Activity
Signal Transduction
Intracellular Signal Transduction
Pathways
Peptide hormone metabolism
Cargo trafficking to the periciliary membrane
Organelle biogenesis and maintenance
Translocation of GLUT4 to the plasma membrane
VxPx cargo-targeting to cilium
Assembly of the primary cilium
Insulin processing
Drugs
Diseases
GWAS
Cervical cancer (
23817570
)
Alcohol and nictotine co-dependence (
22488850
)
Alcohol dependence (
21956439
)
Protein-Protein Interactions
28 interactors:
ATG14
CCDC88A
CCDC93
CCSER2
CDC5L
CEP295
COLEC12
DISC1
DST
GOLGA4
KANSL1
KDM1A
KIAA0226
KIAA1551
KIF5A
LUC7L2
MACF1
NUF2
RALA
RB1CC1
SFR1
SH3BP5
SPTAN1
SRGAP2
SYBU
TRAF3IP1
TRIM9
TRIO
14 interactors:
APP
BTK
CDC5L
DISC1
DST
EXOC1
MAPK10
MAPK12
MAPK8
MAPK9
SOS1
SPTBN1
SYNE1
TNKS
Entrez ID
55763
9467
HPRD ID
07615
12030
Ensembl ID
ENSG00000090989
ENSG00000131370
Uniprot IDs
Q9NV70
O60239
PDB IDs
4H3B
Enriched GO Terms of Interacting Partners
?
Golgi To Plasma Membrane Transport
Movement Of Cell Or Subcellular Component
Regulation Of Cellular Component Organization
Locomotion
Nervous System Development
Post-Golgi Vesicle-mediated Transport
Microtubule-based Process
Regulation Of Cell Projection Organization
Generation Of Neurons
Regulation Of Autophagy
TOR Signaling
Organelle Organization
Golgi To Plasma Membrane Protein Transport
Neurogenesis
Regulation Of Cell Size
Regulation Of Cellular Component Size
Chemotaxis
Intracellular Signal Transduction
Cellular Component Assembly
Regulation Of Neuron Projection Development
Vesicle-mediated Transport
Autophagy
Cellular Localization
Axon Guidance
Regulation Of Neurogenesis
Positive Regulation Of Axon Extension
Autophagic Vacuole Assembly
Establishment Of Localization In Cell
Regulation Of Primitive Erythrocyte Differentiation
Lamellipodium Assembly Involved In Ameboidal Cell Migration
Lamellipodium Assembly
Microtubule Cytoskeleton Organization
Cell Projection Organization
Cell Communication
Lamellipodium Organization
Positive Regulation Of Neural Precursor Cell Proliferation
Macroautophagy
Cell Projection Morphogenesis
Regulation Of Cell Development
Extension Of A Leading Process Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration
Negative Regulation Of SNARE Complex Assembly
Cell Part Morphogenesis
Cerebral Cortex Radially Oriented Cell Migration
Axonogenesis
Regulation Of Axon Extension
Regulation Of Neuron Differentiation
Regulation Of Organelle Organization
Cell Cycle
Response To External Stimulus
Golgi Vesicle Transport
JUN Phosphorylation
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Cell Surface Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Protein Phosphorylation
Fc Receptor Signaling Pathway
Toll-like Receptor Signaling Pathway
Signal Transduction
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Signaling
Cell Communication
Phosphorylation
Intracellular Signal Transduction
Positive Regulation Of Innate Immune Response
Innate Immune Response
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Immune Response-regulating Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MAPK Cascade
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Innate Immune Response
Cellular Response To Stimulus
Signal Transduction By Phosphorylation
JNK Cascade
Cellular Localization
Positive Regulation Of Proteolysis
Regulation Of Circadian Rhythm
Response To Stress
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Response To Light Stimulus
Apoptotic Signaling Pathway
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Peptidyl-serine Phosphorylation
Positive Regulation Of Signal Transduction
Immune Response
Defense Response
Phosphate-containing Compound Metabolic Process
Positive Regulation Of Peptidase Activity
Regulation Of Immune Response
Tagcloud
?
activator
apollon
bioactive
bruce
context
deaths
effector
familial
heterotrimeric
hthnr
humanin
inhibits
jaks
janus
linked
london
member
neuronal
occurs
precursor
sole
stat3
transducer
unusual
upregulated
v642i
variety
via
Tagcloud (Difference)
?
activator
apollon
bioactive
bruce
context
deaths
effector
familial
heterotrimeric
hthnr
humanin
inhibits
jaks
janus
linked
london
member
neuronal
occurs
precursor
sole
stat3
transducer
unusual
upregulated
v642i
variety
via
Tagcloud (Intersection)
?