EXOC1 and NUF2

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		EXOC1	NUF2
Gene Name		exocyst complex component 1	NUF2, NDC80 kinetochore complex component
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Cytosol Plasma Membrane Membrane	Chromosome, Centromeric Region Condensed Chromosome Kinetochore Nucleus Cytosol Membrane Ndc80 Complex
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	Exocytosis Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Cell Division
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Cervical cancer ( 23817570)
Protein-Protein Interactions		28 interactors: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST GOLGA4 KANSL1 KDM1A KIAA0226 KIAA1551 KIF5A LUC7L2 MACF1 NUF2 RALA RB1CC1 SFR1 SH3BP5 SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO	10 interactors: ATF3 AURKA AURKB AZGP1 CENPE CENPH DTNBP1 EXOC1 NDC80 SDCBP2
Entrez ID		55763	83540
HPRD ID		07615	10817
Ensembl ID		ENSG00000090989	ENSG00000143228
Uniprot IDs		Q9NV70	Q9BZD4
PDB IDs			2VE7 3IZ0
Enriched GO Terms of Interacting Partners?		Golgi To Plasma Membrane Transport Movement Of Cell Or Subcellular Component Regulation Of Cellular Component Organization Locomotion Nervous System Development Post-Golgi Vesicle-mediated Transport Microtubule-based Process Regulation Of Cell Projection Organization Generation Of Neurons Regulation Of Autophagy TOR Signaling Organelle Organization Golgi To Plasma Membrane Protein Transport Neurogenesis Regulation Of Cell Size Regulation Of Cellular Component Size Chemotaxis Intracellular Signal Transduction Cellular Component Assembly Regulation Of Neuron Projection Development Vesicle-mediated Transport Autophagy Cellular Localization Axon Guidance Regulation Of Neurogenesis Positive Regulation Of Axon Extension Autophagic Vacuole Assembly Establishment Of Localization In Cell Regulation Of Primitive Erythrocyte Differentiation Lamellipodium Assembly Involved In Ameboidal Cell Migration Lamellipodium Assembly Microtubule Cytoskeleton Organization Cell Projection Organization Cell Communication Lamellipodium Organization Positive Regulation Of Neural Precursor Cell Proliferation Macroautophagy Cell Projection Morphogenesis Regulation Of Cell Development Extension Of A Leading Process Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Negative Regulation Of SNARE Complex Assembly Cell Part Morphogenesis Cerebral Cortex Radially Oriented Cell Migration Axonogenesis Regulation Of Axon Extension Regulation Of Neuron Differentiation Regulation Of Organelle Organization Cell Cycle Response To External Stimulus Golgi Vesicle Transport See more	Attachment Of Spindle Microtubules To Kinetochore Mitotic Spindle Organization Spindle Stabilization Attachment Of Mitotic Spindle Microtubules To Kinetochore Microtubule Anchoring Mitotic Nuclear Division Mitotic Cell Cycle Microtubule-based Process Cellular Localization Histone-serine Phosphorylation Spindle Organization Organelle Localization Cell Division Microtubule Cytoskeleton Organization Maintenance Of Protein Location In Cell Maintenance Of Protein Location Organelle Assembly Chromosome Organization Kinetochore Assembly Maintenance Of Location In Cell Protein Localization Cytoskeleton Organization Organelle Organization Kinetochore Organization Histone Phosphorylation Negative Regulation Of Microtubule Depolymerization Chromosome Segregation Cell Cycle Mitotic Cell Cycle Process Regulation Of Cell Division Centromere Complex Assembly Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Cytokinesis Negative Regulation Of Protein Binding Establishment Of Organelle Localization Cellular Protein Complex Assembly Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Spindle Checkpoint Mitotic Sister Chromatid Segregation Spindle Assembly Protein Complex Assembly Sister Chromatid Segregation Cell Cycle Process Negative Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Negative Regulation Of Binding Spindle Assembly Involved In Female Meiosis I Regulation Of Cell Cycle Process Regulation Of Protein Depolymerization See more
Tagcloud ?			ams2 ams2p bioinformatics cenpa centromere centromeres centromeric cnp1 cnp1p defining disrupted gata identifies incorporation kinetochore linker mal2 microarrays mis12 mis18 nucleosome nucleosomes participating pombe positioned positioning regularly schizosaccharomyces tiling
Tagcloud (Difference) ?			ams2 ams2p bioinformatics cenpa centromere centromeres centromeric cnp1 cnp1p defining disrupted gata identifies incorporation kinetochore linker mal2 microarrays mis12 mis18 nucleosome nucleosomes participating pombe positioned positioning regularly schizosaccharomyces tiling
Tagcloud (Intersection) ?