INVS and ZNF512B

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)

		INVS	ZNF512B
Gene Name		inversin	zinc finger protein 512B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Spindle Microtubule Membrane Ciliary Inversin Compartment Ciliary Base	Nucleus
	Molecular Function	Protein Binding Calmodulin Binding	DNA Binding Metal Ion Binding
	Biological Process	Kidney Development Post-embryonic Development Wnt Signaling Pathway Pancreas Development Embryonic Heart Tube Left/right Pattern Formation Negative Regulation Of Canonical Wnt Signaling Pathway	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Preeclampsia ( 23551011)	Prostate cancer ( 23535732)
Protein-Protein Interactions		4 interactors: CALM2 HIF1AN NPHP1 ZNF512B	60 interactors: ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BRD1 BTBD2 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FAM129B FHL3 GLRX3 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MYH10 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2
Entrez ID		27130	57473
HPRD ID		08356	13840
Ensembl ID		ENSG00000119509	ENSG00000196700
Uniprot IDs		F5GZH2 Q2M1I4 Q9Y283	Q96KM6
PDB IDs			2GQJ
Enriched GO Terms of Interacting Partners?		Peptidyl-histidine Hydroxylation Peptidyl-asparagine Hydroxylation Peptidyl-aspartic Acid Hydroxylation Response To Abiotic Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of High Voltage-gated Calcium Channel Activity Response To Light Stimulus Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Photoreceptor Cell Outer Segment Organization Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Positive Regulation Of Vasculogenesis Regulation Of Cell Communication By Electrical Coupling Response To Radiation Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Regulation Of Vasculogenesis Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Myoblast Differentiation Negative Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Dephosphorylation Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Protein Hydroxylation Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Negative Regulation Of Notch Signaling Pathway Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine Regulation Of Phosphoprotein Phosphatase Activity	Regulation Of Cellular Process Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organ Development System Development Transcription, DNA-templated Developmental Process Chromosome Organization Anatomical Structure Development Regulation Of Gene Expression RNA Biosynthetic Process Response To Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Biosynthetic Process Cell Cycle Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Cycle Process Multicellular Organismal Development Viral Genome Replication Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Organization Wnt Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cell Surface Receptor Signaling Pathway Organelle Organization Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Chromatin Remodeling RNA Metabolic Process Primary MiRNA Processing Vesicle-mediated Transport Endosomal Transport Regulation Of Signal Transduction Cellular Response To Stress Mitotic Cell Cycle Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Response To Stress Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		adjunct attempted chromogranin clarify colitis comparatively coordinately crucially diffuse dysplasia dysplasias focal grading hgd hgds immunoreactive lgd lgds mucosa neoplasia neoplastic neuroendocrine pancellular positivity predictive tended uc ulcerative utility
Tagcloud (Difference) ?		adjunct attempted chromogranin clarify colitis comparatively coordinately crucially diffuse dysplasia dysplasias focal grading hgd hgds immunoreactive lgd lgds mucosa neoplasia neoplastic neuroendocrine pancellular positivity predictive tended uc ulcerative utility
Tagcloud (Intersection) ?