STAT5A and PTPN11

  • Number of citations of the paper that reports this interaction (PMID 10617656)
  • 35
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, in vivo)

STAT5A

PTPN11

Gene Name signal transducer and activator of transcription 5A protein tyrosine phosphatase, non-receptor type 11
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 72 interactors: AQP11 BMX BRCA1 BRCA2 BTK CBL CCR5 CD247 CEBPB CENPJ CRK CRKL CSNK2B CTLA4 CYP2C9 EGFR EP300 EPAS1 EPOR ERBB4 ESR1 ESR2 FN1 GHR GLUD1 GNB2 HELZ IL2RB IL2RG IL7R INSR JAK1 JAK2 JAK3 KIT LCK LEF1 MAGEA12 MAPK1 MAPK3 MRPS6 NARF NCOR2 NLK NMI NR3C1 PDGFRA PDGFRB POM121C POU2F1 PPIB PPP2CA PRMT1 PRTFDC1 PTPN1 PTPN11 PTPN2 RBMX SHC1 SRC STAP2 STAT1 STAT3 STAT5B SYK TCF12 TEK TSLP TXNDC11 UGT2B4 WASH2P ZNF596 114 interactors: ACTN4 ARHGAP1 AXL BCR BDKRB2 BTLA C6orf25 CAT CAV1 CBL CCKBR CD33 CDH5 CEACAM1 CHUK CRKL CSF2RB CSF3R CTLA4 CXCR4 DAB1 DDR1 EGFR EPHA2 EPOR ERBB2 FCRL3 FLT1 FLT4 FRS2 FRS3 FYN GAB1 GAB2 GAB3 GHR GRB2 GRIN2B HNRNPU IFNAR1 IFNGR1 IGF1R IL4R IL6ST INPP5D INSR IRS1 IRS2 IRS4 JAK1 JAK2 KDR KIR2DL5A KIT KLRC1 LAIR1 LCK LEPR LIFR LILRB4 MAP3K4 MAP3K5 MAPK3 MET MPL MPZL1 MS4A2 MVP NEDD9 NTRK1 NTRK2 PAG1 PDGFRA PDGFRB PECAM1 PIK3CG PIK3R1 PILRA PILRB PLCG1 PRKCA PRKCB PRKCH PRLR PTK2 PTK2B PTPN6 PXN RET ROS1 RPIA SELE SHC1 SIGLEC11 SIGLEC12 SIGLEC7 SIRPA SIT1 SLAMF1 SLAMF6 SOCS3 SOS1 SPRY2 SRC STAT1 STAT3 STAT5A STAT5B SYNCRIP TEK TIE1 TNFRSF1A TREML1 TRIM32
Entrez ID 6776 5781
HPRD ID 03301 01470
Ensembl ID ENSG00000126561 ENSG00000179295
Uniprot IDs A8K6I5 K7EK35 P42229 Q59GY7 Q06124
PDB IDs 2SHP 3B7O 3MOW 3O5X 3TKZ 3TL0 4DGP 4DGX 4GWF 4H1O 4H34 4JE4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
advantaged  apor  arose  b8  ba  character  coincides  committed  derive  die  dn  epo  epor  erythropoietin  f3epor  homeotic  hox  hypothesize  naturally  normally  preexisting  shortened  subclones  switch  truncated  unexplored  uniquely 
absolute  case  cases  count  died  eleven  female  indispensable  interval  jmml  juvenile  male  median  monocytes  mutation  myelomonocytic  observation  obviously  onset  peripheral  platelet  plt  progressive  ras  retrospectively  slow  sure  wbc  white 
Tagcloud (Difference) ?
advantaged  apor  arose  b8  ba  character  coincides  committed  derive  die  dn  epo  epor  erythropoietin  f3epor  homeotic  hox  hypothesize  naturally  normally  preexisting  shortened  subclones  switch  truncated  unexplored  uniquely 
absolute  case  cases  count  died  eleven  female  indispensable  interval  jmml  juvenile  male  median  monocytes  mutation  myelomonocytic  observation  obviously  onset  peripheral  platelet  plt  progressive  ras  retrospectively  slow  sure  wbc  white 
Tagcloud (Intersection) ?