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HEYL and ZNF512B
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid)
HEYL
ZNF512B
Gene Name
hes-related family bHLH transcription factor with YRPW motif-like
zinc finger protein 512B
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nucleus
Molecular Function
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding Transcription Factor Activity
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
RNA Polymerase II Transcription Corepressor Activity
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
Microsatellite Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
AF-1 Domain Binding
DNA Binding
Metal Ion Binding
Biological Process
Outflow Tract Morphogenesis
Atrioventricular Valve Morphogenesis
Pulmonary Valve Morphogenesis
Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Endocardial Cushion Morphogenesis
Cardiac Ventricle Morphogenesis
Transcription From RNA Polymerase II Promoter
Notch Signaling Pathway
Mesenchymal Cell Development
Glomerulus Development
Skeletal Muscle Cell Differentiation
Positive Regulation Of Neuron Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cardiac Epithelial To Mesenchymal Transition
Ventricular Septum Morphogenesis
Negative Regulation Of Androgen Receptor Signaling Pathway
Cellular Response To BMP Stimulus
Proximal Tubule Development
Negative Regulation Of Androgen Receptor Activity
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Pathways
Signaling by NOTCH1 HD Domain Mutants in Cancer
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
Signaling by NOTCH
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
NOTCH1 Intracellular Domain Regulates Transcription
Signaling by NOTCH1
Signaling by NOTCH1 PEST Domain Mutants in Cancer
Signaling by NOTCH1 in Cancer
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Constitutive Signaling by NOTCH1 PEST Domain Mutants
FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS
Red blood cell traits (
23222517
)
Prostate cancer (
23535732
)
Protein-Protein Interactions
18 interactors:
APP
ATF7IP
ATXN1
HAND1
HAND2
HIPK3
HTT
LAPTM5
MDFI
PPP1CA
RBPMS
RPGRIP1
SKIL
SMAD3
SMAD7
SMAD9
SP8
ZNF512B
60 interactors:
ANKLE2
ANKRD28
AP1G1
APLP2
ATRX
BRD1
BTBD2
CDC123
CREBZF
CTBP2
DCTN1
DDX3X
DROSHA
DVL3
EHMT2
FAM129B
FHL3
GLRX3
HEYL
HTATSF1
IL36RN
INVS
KDM2A
KDM3B
KLF10
KMT2B
L1TD1
LAMB2
LZTS2
MBD1
MYH10
OS9
PAPPA2
PBRM1
PDE4DIP
PEG10
PIAS4
PLCG2
PPP1R15A
PTPRF
RPS27A
SDF4
SIAH1
SMAD1
SPTBN1
SUPT5H
TGM2
TNKS2
TOM1
TOX4
TRAF1
TRAF4
VHL
VPS35
VPS41
VWF
XPC
XRCC6
YES1
ZMYM2
Entrez ID
26508
57473
HPRD ID
16419
13840
Ensembl ID
ENSG00000163909
ENSG00000196700
Uniprot IDs
F5H3V9
Q9NQ87
Q96KM6
PDB IDs
2GQJ
Enriched GO Terms of Interacting Partners
?
Regulation Of Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Anatomical Structure Morphogenesis
RNA Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Organ Development
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Transforming Growth Factor Beta Stimulus
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Response To Transforming Growth Factor Beta
Heterocycle Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Tube Development
Epithelium Development
Negative Regulation Of Signal Transduction
Positive Regulation Of Gene Expression
Regulation Of Metabolic Process
Regulation Of Signal Transduction
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Pattern Specification Process
Negative Regulation Of Signaling
Regulation Of Binding
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Macromolecule Biosynthetic Process
Tissue Development
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Signaling
Positive Regulation Of Transcription, DNA-templated
Multicellular Organismal Development
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cardiac Right Ventricle Formation
Anatomical Structure Development
Positive Regulation Of Cellular Metabolic Process
Organ Morphogenesis
Negative Regulation Of DNA Binding
Embryonic Morphogenesis
System Development
Regulation Of Cellular Process
Negative Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Organ Development
System Development
Transcription, DNA-templated
Developmental Process
Chromosome Organization
Anatomical Structure Development
Regulation Of Gene Expression
RNA Biosynthetic Process
Response To Stimulus
Negative Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression, Epigenetic
Chromatin Modification
Negative Regulation Of Biosynthetic Process
Cell Cycle
Cellular Response To Stimulus
Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cell Cycle Process
Multicellular Organismal Development
Viral Genome Replication
Positive Regulation Of Macromolecule Biosynthetic Process
Chromatin Organization
Wnt Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Cell Surface Receptor Signaling Pathway
Organelle Organization
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Metabolic Process
Chromatin Remodeling
RNA Metabolic Process
Primary MiRNA Processing
Vesicle-mediated Transport
Endosomal Transport
Regulation Of Signal Transduction
Cellular Response To Stress
Mitotic Cell Cycle Process
Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Gene Expression
Response To Stress
Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud
?
bad
bromide
cancerous
dimethylthiazol
diphenyltetrazolium
egfp
eighty
expressional
hairy
hcc
hep
hypermethylation
inactivated
lentiviral
overexpress
p19
pheyl
preceded
qpcr
repressor
resected
ribose
shheyl
silence
sk
split
surgically
yrpw
Tagcloud (Difference)
?
bad
bromide
cancerous
dimethylthiazol
diphenyltetrazolium
egfp
eighty
expressional
hairy
hcc
hep
hypermethylation
inactivated
lentiviral
overexpress
p19
pheyl
preceded
qpcr
repressor
resected
ribose
shheyl
silence
sk
split
surgically
yrpw
Tagcloud (Intersection)
?