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HEYL
Gene Name
hes-related family bHLH transcription factor with YRPW motif-like
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding Transcription Factor Activity
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
RNA Polymerase II Transcription Corepressor Activity
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
Microsatellite Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
AF-1 Domain Binding
Biological Process
Outflow Tract Morphogenesis
Atrioventricular Valve Morphogenesis
Pulmonary Valve Morphogenesis
Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Endocardial Cushion Morphogenesis
Cardiac Ventricle Morphogenesis
Transcription From RNA Polymerase II Promoter
Notch Signaling Pathway
Mesenchymal Cell Development
Glomerulus Development
Skeletal Muscle Cell Differentiation
Positive Regulation Of Neuron Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cardiac Epithelial To Mesenchymal Transition
Ventricular Septum Morphogenesis
Negative Regulation Of Androgen Receptor Signaling Pathway
Cellular Response To BMP Stimulus
Proximal Tubule Development
Negative Regulation Of Androgen Receptor Activity
Pathways
Signaling by NOTCH1 HD Domain Mutants in Cancer
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
Signaling by NOTCH
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
NOTCH1 Intracellular Domain Regulates Transcription
Signaling by NOTCH1
Signaling by NOTCH1 PEST Domain Mutants in Cancer
Signaling by NOTCH1 in Cancer
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Constitutive Signaling by NOTCH1 PEST Domain Mutants
FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS
Red blood cell traits (
23222517
)
Protein-protein Interactions
18 interactors:
APP
ATF7IP
ATXN1
HAND1
HAND2
HIPK3
HTT
LAPTM5
MDFI
PPP1CA
RBPMS
RPGRIP1
SKIL
SMAD3
SMAD7
SMAD9
SP8
ZNF512B
Entrez ID
26508
HPRD ID
16419
Ensembl ID
ENSG00000163909
Uniprot IDs
F5H3V9
Q9NQ87
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Anatomical Structure Morphogenesis
RNA Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Organ Development
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Transforming Growth Factor Beta Stimulus
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Response To Transforming Growth Factor Beta
Heterocycle Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Tube Development
Epithelium Development
Negative Regulation Of Signal Transduction
Positive Regulation Of Gene Expression
Regulation Of Metabolic Process
Regulation Of Signal Transduction
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Pattern Specification Process
Negative Regulation Of Signaling
Regulation Of Binding
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Macromolecule Biosynthetic Process
Tissue Development
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Signaling
Positive Regulation Of Transcription, DNA-templated
Multicellular Organismal Development
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cardiac Right Ventricle Formation
Anatomical Structure Development
Positive Regulation Of Cellular Metabolic Process
Organ Morphogenesis
Negative Regulation Of DNA Binding
Embryonic Morphogenesis
System Development
Tagcloud
?
bad
bromide
cancerous
dimethylthiazol
diphenyltetrazolium
egfp
eighty
expressional
hairy
hcc
hep
hypermethylation
inactivated
lentiviral
overexpress
p19
pheyl
preceded
qpcr
repressor
resected
ribose
shheyl
silence
sk
split
surgically
yrpw