TES and VASP

Number of citations of the paper that reports this interaction (PubMedID 12695497)
17

Data Source:
HPRD (in vitro)

		TES	VASP
Description		testin LIM domain protein	vasodilator stimulated phosphoprotein
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Cell Junction Protein-containing Complex Anchoring Junction	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Bicellular Tight Junction Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Filopodium Lamellipodium Membrane Filopodium Membrane Cell Projection Extracellular Exosome Anchoring Junction Postsynapse Glutamatergic Synapse
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Cadherin Binding Metal Ion Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Cadherin Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Protein Homotetramerization
Pathways			Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Chronotype ( 30696823) Glaucoma ( 30054594 31959993) Intraocular pressure ( 29235454 30054594 31959993) Metabolite levels ( 23823483) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)	Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
Interacting Genes		13 interacting genes: ACTL7A ACTN1 ALKBH4 ARAP1 ENAH EVL GRIPAP1 SOCS3 SPOCK2 SPTAN1 TLN1 VASP ZYX	49 interacting genes: ABI1 ABI2 ABI3 ACTA1 ACTG1 AEBP1 APBB1 APBB1IP CDC42 CEBPA DMRTB1 DNMBP ENAH ERMAP FAF2 FAT1 FRS3 FYB1 GSN IQGAP1 LPP MAGED1 MRPL43 NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A PSORS1C2 RAD51 RAPH1 SAT1 SCGB2A2 SHROOM3 SPTA1 TES TRIM15 TRIM9 VCL WAS WASL WWP2 XIRP1 XIRP2 XPO6 ZYX
Entrez ID		26136	7408
HPRD ID		05833	03415
Ensembl ID		ENSG00000135269	ENSG00000125753
Uniprot IDs		A4D0U5 Q9UGI8	A0A024R0V4 P50552
PDB IDs		2IYB 2XQN	1EGX 1USD 1USE 2PAV 2PBD 3CHW 8GAT 8GAU
Enriched GO Terms of Interacting Partners?		Actin Binding Actin Filament Organization Supramolecular Fiber Organization Profilin Binding Cytoskeleton Organization Actin Cytoskeleton Organization Actin Filament-based Process Anchoring Junction Focal Adhesion Cell Projection Cytoskeleton Actin Polymerization Or Depolymerization Vinculin Binding Stress Fiber Regulation Of Actin Filament Organization Structural Constituent Of Cytoskeleton Ruffle SH3 Domain Binding Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament Polymerization Organelle Organization Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Lamellipodium Cell-substrate Junction Assembly Actin Filament Binding Cell-substrate Junction Organization Regulation Of Cytoskeleton Organization Neuron Projection Guidance Axon Guidance Platelet Aggregation Positive Regulation Of Actin Filament Polymerization DNA N6-methyladenine Demethylase Activity Extrinsic Component Of Postsynaptic Early Endosome Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Cortical Actin Cytoskeleton Cellular Component Assembly Regulation Of Cellular Component Size Cell Junction Assembly Cytosol Protein Homotetramerization Actin Filament Bundle Assembly Homotypic Cell-cell Adhesion Actin Cytoskeleton Actin Filament Bundle Organization Structural Constituent Of Postsynapse Cleavage Furrow Ingression Negative Regulation Of Receptor Clustering	Actin Filament Organization Focal Adhesion Lamellipodium Supramolecular Fiber Organization Actin Filament-based Process Anchoring Junction Actin Cytoskeleton Organization Cytoskeleton Filopodium Actin Cytoskeleton Cytoplasm Actin Binding Actin Polymerization Or Depolymerization Regulation Of Actin Filament Organization Cytoskeleton Organization Cell-cell Junction Regulation Of Actin Cytoskeleton Organization Cytosol Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Actin-based Cell Projection Actin Filament Binding Cellular Response To Type II Interferon SCAR Complex Phagocytic Vesicle Regulation Of Cell Projection Assembly Regulation Of Lamellipodium Assembly Actin Filament Stress Fiber Modification Of Postsynaptic Actin Cytoskeleton Regulation Of Stress Fiber Assembly Organelle Organization Response To Type II Interferon Cell Projection Morphogenesis Regulation Of Lamellipodium Organization Regulation Of Cytoskeleton Organization Adherens Junction SH3 Domain Binding Cortical Actin Cytoskeleton Modification Of Postsynaptic Structure Negative Regulation Of Cellular Component Organization Cell Leading Edge Modification Of Synaptic Structure Cell Projection Organization Cell Junction Organization Actin Cap Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Ruffle Assembly Actin Filament Polymerization
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