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TES and ARAP1
Number of citations of the paper that reports this interaction (PubMedID
21275903
)
45
Data Source:
BioGRID
(two hybrid)
TES
ARAP1
Description
testin LIM domain protein
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Focal Adhesion
Cell Junction
Protein-containing Complex
Anchoring Junction
Ruffle
Podosome
Nucleoplasm
Cytoplasm
Endosome
Early Endosome
Multivesicular Body
Golgi Apparatus
Golgi Stack
Trans-Golgi Network
Cytosol
Plasma Membrane
Membrane
Extrinsic Component Of Plasma Membrane
Cell Projection
Anchoring Junction
Molecular Function
RNA Binding
Protein Binding
Zinc Ion Binding
Cadherin Binding
Metal Ion Binding
GTPase Activator Activity
Protein Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Zinc Ion Binding
Type 1 Angiotensin Receptor Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Receptor Recycling
Regulation Of Receptor Internalization
Actin Filament Organization
Signal Transduction
Regulation Of Cell Shape
Regulation Of Endocytosis
Regulation Of Cell Projection Organization
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of GTPase Activity
Regulation Of Bone Resorption
Photoreceptor Cell Maintenance
Positive Regulation Of Phagocytosis
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Cellular Component Organization
Positive Regulation Of Filopodium Assembly
Negative Regulation Of Stress Fiber Assembly
Pathways
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
RHOA GTPase cycle
CDC42 GTPase cycle
RAC1 GTPase cycle
Drugs
Diseases
GWAS
Chronotype (
30696823
)
Glaucoma (
30054594
31959993
)
Intraocular pressure (
29235454
30054594
31959993
)
Metabolite levels (
23823483
)
Schizophrenia, bipolar disorder or major depressive disorder (
34099189
)
Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (
34099189
)
Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction (
34099189
)
Acute insulin response (
28490609
)
Alcohol dependence symptom count (
29460428
)
Alloimmunization response to red blood cell transfusion in sickle cell anemia (
25670933
)
Body fat percentage and fasting glucose (pairwise) (
33619380
)
Body fat percentage and type 2 diabetes (pairwise) (
33619380
)
Body mass index (
25673413
28892062
)
Body mass index and fasting glucose (pairwise) (
33619380
)
Body mass index and type 2 diabetes (pairwise) (
33619380
)
Fasting blood glucose (
22581228
25631608
)
Fasting blood glucose (BMI interaction) (
22581228
)
Fasting blood proinsulin levels (
23263489
)
Fasting glucose (
34059833
)
Glycated hemoglobin levels (
28898252
)
Household income (MTAG) (
31844048
)
Insulin-related traits (multivariate analysis) (
32002517
)
Mean platelet volume (
32888494
27863252
)
Mean spheric corpuscular volume (
32888494
)
Medication use (drugs used in diabetes) (
31015401
)
Proinsulin levels (
21873549
)
Rheumatoid arthritis (
22446963
)
Type 2 diabetes (
30297969
30718926
30054458
26961502
29358691
32499647
28869590
26818947
24509480
22885922
)
Waist circumference (
28552196
)
Waist circumference adjusted for body mass index (
28552196
)
Interacting Genes
13 interacting genes:
ACTL7A
ACTN1
ALKBH4
ARAP1
ENAH
EVL
GRIPAP1
SOCS3
SPOCK2
SPTAN1
TLN1
VASP
ZYX
15 interacting genes:
APP
ARIH2
ARPC3
CDC42
FGFR3
FILNC1
INPP5D
KCTD12
PSD3
RAC1
TAB1
TES
TP53BP1
WAPL
XRCC6
Entrez ID
26136
116985
HPRD ID
05833
09440
Ensembl ID
ENSG00000135269
ENSG00000186635
Uniprot IDs
A4D0U5
Q9UGI8
E7EU13
Q96P48
PDB IDs
2IYB
2XQN
4X1V
Enriched GO Terms of Interacting Partners
?
Actin Binding
Actin Filament Organization
Supramolecular Fiber Organization
Profilin Binding
Cytoskeleton Organization
Actin Cytoskeleton Organization
Actin Filament-based Process
Anchoring Junction
Focal Adhesion
Cell Projection
Cytoskeleton
Actin Polymerization Or Depolymerization
Vinculin Binding
Stress Fiber
Regulation Of Actin Filament Organization
Structural Constituent Of Cytoskeleton
Ruffle
SH3 Domain Binding
Regulation Of Actin Cytoskeleton Organization
Regulation Of Actin Filament Polymerization
Organelle Organization
Regulation Of Actin Filament-based Process
Regulation Of Supramolecular Fiber Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Lamellipodium
Cell-substrate Junction Assembly
Actin Filament Binding
Cell-substrate Junction Organization
Regulation Of Cytoskeleton Organization
Neuron Projection Guidance
Axon Guidance
Platelet Aggregation
Positive Regulation Of Actin Filament Polymerization
DNA N6-methyladenine Demethylase Activity
Extrinsic Component Of Postsynaptic Early Endosome Membrane
Regulation Of Recycling Endosome Localization Within Postsynapse
Cortical Actin Cytoskeleton
Cellular Component Assembly
Regulation Of Cellular Component Size
Cell Junction Assembly
Cytosol
Protein Homotetramerization
Actin Filament Bundle Assembly
Homotypic Cell-cell Adhesion
Actin Cytoskeleton
Actin Filament Bundle Organization
Structural Constituent Of Postsynapse
Cleavage Furrow Ingression
Negative Regulation Of Receptor Clustering
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Thioesterase Binding
G Protein-coupled Receptor Signaling Pathway Involved In Heart Process
Focal Adhesion
Cellular Response To X-ray
Double-strand Break Repair Via Classical Nonhomologous End Joining
Positive Regulation Of Immune System Process
Positive Regulation Of Phosphate Metabolic Process
Positive Regulation Of Cell Activation
Regulation Of Signal Transduction
Regulation Of Supramolecular Fiber Organization
Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Regulation Of Postsynapse Organization
Positive Regulation Of Intracellular Signal Transduction
Regulation Of MAPK Cascade
Regulation Of Endocytosis
Positive Regulation Of Lamellipodium Assembly
GTP-dependent Protein Binding
Phagocytosis, Engulfment
Telomeric DNA Binding
Hyperosmotic Response
Response To X-ray
Regulation Of Synaptic Vesicle Endocytosis
Regulation Of Synaptic Vesicle Recycling
Negative Regulation Of DNA Replication
Intracellular Signal Transduction
Positive Regulation Of Supramolecular Fiber Organization
Protein-containing Complex
Cell Projection
Positive Regulation Of Lamellipodium Organization
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Regulation Of Innate Immune Response
Regulation Of Lamellipodium Assembly
Positive Regulation Of MAPK Cascade
Protein Homooligomerization
Neuron Projection Organization
Intracellular Signaling Cassette
Receptor Complex
Cellular Response To Nerve Growth Factor Stimulus
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Amyloid-beta Complex
Growth Cone Lamellipodium
Regulation Of Response To Calcium Ion
Response To Nerve Growth Factor
Amylin Binding
Positive Regulation Of Toll Signaling Pathway
Dendrite Development
Regulation Of Cell Communication
Regulation Of Intracellular Signal Transduction
Regulation Of Signaling
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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