BRMS1 and DNAJB6

Number of citations of the paper that reports this interaction (PMID 16919237)
26

Data Source:
HPRD (in vivo, two hybrid)

		BRMS1	DNAJB6
Gene Name		breast cancer metastasis suppressor 1	DnaJ (Hsp40) homolog, subfamily B, member 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding	ATPase Activator Activity Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Protein Folding Positive Regulation Of ATPase Activity Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Inclusion Body Assembly
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		36 interactors: APP ARID4A BRMS1L CEP70 DNAJB1 DNAJB6 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 ING1 KPNA5 LINC00152 LRIF1 NMI PFDN5 RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNX6 SPOP SUDS3 TAF1 UBE2D1	6 interactors: APP BRMS1 KRT18 PIK3CA POLR1D USP8
Entrez ID		25855	10049
HPRD ID		05879	07107
Ensembl ID		ENSG00000174744	ENSG00000105993
Uniprot IDs		G5E9I4 Q9HCU9	B4DN73 E9PH18 O75190
PDB IDs		2XUS 4AUV
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Modification Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Protein Deacetylation Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Histone H3-K9 Modification Chromosome Organization Negative Regulation Of Biosynthetic Process Histone Modification Negative Regulation Of Cellular Metabolic Process Organelle Organization Negative Regulation Of Gene Expression, Epigenetic Histone H4 Deacetylation Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Histone H3 Deacetylation Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Gene Expression Cellular Response To Heat Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromatin Remodeling Positive Regulation Of Macromolecule Biosynthetic Process Response To Heat Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process ATP-dependent Chromatin Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process	Regulation Of Anoikis Regulation Of Multicellular Organism Growth Golgi To Plasma Membrane CFTR Protein Transport Hypomethylation Of CpG Island Synaptic Growth At Neuromuscular Junction Regulation Of Cellular Protein Metabolic Process Innate Immune Response Collateral Sprouting In Absence Of Injury Regulation Of Protein Metabolic Process Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Positive Regulation Of Anoikis Platelet Activation Collateral Sprouting Axon Midline Choice Point Recognition Apoptotic Process Programmed Cell Death Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Genetic Imprinting Cell Death Death Axon Choice Point Recognition Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Developmental Growth Neuron Remodeling Positive Regulation Of Protein Metabolic Process Negative Regulation Of Fibroblast Apoptotic Process Immune Response Defense Response Negative Regulation Of Anoikis Vesicle-mediated Transport Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Apoptotic Process Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Cellular Protein Modification Process Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Blood Coagulation Cellular Copper Ion Homeostasis Hemostasis Regulation Of Cell Death Endomembrane System Organization Regulation Of DNA Methylation Regulation Of Fibroblast Apoptotic Process Hepatocyte Apoptotic Process Phosphatidylinositol-3-phosphate Biosynthetic Process Copper Ion Homeostasis Suckling Behavior Golgi To Plasma Membrane Protein Transport Regulation Of Cellular Ketone Metabolic Process
Tagcloud ?		adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic	alphab bag3 biomechanical carrying crystallin deformation desmin disability fhl fiber filamin hereditary mechanical mfms myoblasts myofibrillar myopathies myotilin physiologic plectin premature shear sporadic stiffness stretch trigger vcp vulnerability zasp
Tagcloud (Difference) ?		adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic	alphab bag3 biomechanical carrying crystallin deformation desmin disability fhl fiber filamin hereditary mechanical mfms myoblasts myofibrillar myopathies myotilin physiologic plectin premature shear sporadic stiffness stretch trigger vcp vulnerability zasp
Tagcloud (Intersection) ?