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BRMS1
Gene Name
breast cancer metastasis suppressor 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Sin3-type Complex
Molecular Function
Histone Deacetylase Activity
Protein Binding
Histone Deacetylase Binding
NF-kappaB Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Organization
Transcription, DNA-templated
Apoptotic Process
Histone Deacetylation
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Protein Deacetylation
Positive Regulation Of Anoikis
Pathways
Chromatin modifying enzymes
Chromatin organization
HDACs deacetylate histones
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Protein-protein Interactions
36 interactors:
APP
ARID4A
BRMS1L
CEP70
DNAJB1
DNAJB6
EEF1A1
EP300
GOLGB1
HDAC1
HDAC2
HDAC3
HDAC4
HDAC5
HDAC6
HSP90AA1
HSPA4
ING1
KPNA5
LINC00152
LRIF1
NMI
PFDN5
RBBP4
RBBP7
RBP1
RELA
SAP30
SIN3A
SMARCE1
SMTN
SNX6
SPOP
SUDS3
TAF1
UBE2D1
Entrez ID
25855
HPRD ID
05879
Ensembl ID
ENSG00000174744
Uniprot IDs
G5E9I4
Q9HCU9
PDB IDs
2XUS
4AUV
Enriched GO Terms of Interacting Partners
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Chromatin Organization
Chromatin Modification
Histone Deacetylation
Negative Regulation Of Transcription, DNA-templated
Protein Deacetylation
Negative Regulation Of Gene Expression
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression, Epigenetic
Histone H3-K9 Modification
Chromosome Organization
Negative Regulation Of Biosynthetic Process
Histone Modification
Negative Regulation Of Cellular Metabolic Process
Organelle Organization
Negative Regulation Of Gene Expression, Epigenetic
Histone H4 Deacetylation
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Histone H3 Deacetylation
Regulation Of Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Gene Expression
Regulation Of Gene Expression
Cellular Response To Heat
Regulation Of Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Chromatin Remodeling
Positive Regulation Of Macromolecule Biosynthetic Process
Response To Heat
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
ATP-dependent Chromatin Remodeling
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Protein Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
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ccnd2
cdk2ap1
cdkn1a
cdkn2b
chewing
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fermented
fgfr4
flnc
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hras
il12b
il8
indels
msh6
nbl1
nitrosamines
northeast
nut
quid
rassf1
tobacco
toxogenomic