BRMS1 and BRMS1L

Number of citations of the paper that reports this interaction (PMID 15451426)
21

Data Source:
HPRD (in vivo)

		BRMS1	BRMS1L
Gene Name		breast cancer metastasis suppressor 1	breast cancer metastasis-suppressor 1-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Sin3-type Complex
	Molecular Function	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Histone Deacetylase Activity Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Histone Deacetylation Regulation Of Growth
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		36 interactors: APP ARID4A BRMS1L CEP70 DNAJB1 DNAJB6 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 ING1 KPNA5 LINC00152 LRIF1 NMI PFDN5 RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNX6 SPOP SUDS3 TAF1 UBE2D1	15 interactors: ACTN2 AMOTL2 BRMS1 CCDC67 EXOC5 HDAC1 HDAC2 ING1 LINC00152 MID2 RBBP4 RBBP7 RBP1 SAP30 SIN3A
Entrez ID		25855	84312
HPRD ID		05879	16564
Ensembl ID		ENSG00000174744	ENSG00000100916
Uniprot IDs		G5E9I4 Q9HCU9	B2RD65 Q5PSV4
PDB IDs		2XUS 4AUV
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Modification Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Protein Deacetylation Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Histone H3-K9 Modification Chromosome Organization Negative Regulation Of Biosynthetic Process Histone Modification Negative Regulation Of Cellular Metabolic Process Organelle Organization Negative Regulation Of Gene Expression, Epigenetic Histone H4 Deacetylation Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Histone H3 Deacetylation Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Gene Expression Cellular Response To Heat Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromatin Remodeling Positive Regulation Of Macromolecule Biosynthetic Process Response To Heat Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process ATP-dependent Chromatin Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process	Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Chromatin Organization Chromatin Modification Chromosome Organization Negative Regulation Of Gene Expression Histone Deacetylation Protein Deacetylation Organelle Organization Negative Regulation Of RNA Biosynthetic Process ATP-dependent Chromatin Remodeling Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Histone H3-K9 Modification Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone Modification Regulation Of RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Remodeling Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Fungiform Papilla Formation Fungiform Papilla Morphogenesis Transcription, DNA-templated Positive Regulation Of Receptor Biosynthetic Process Fungiform Papilla Development Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Eyelid Development In Camera-type Eye Hair Follicle Placode Formation Regulation Of Transcription From RNA Polymerase II Promoter Tongue Morphogenesis Regulation Of Receptor Biosynthetic Process Histone H4 Deacetylation Regulation Of Gene Expression Negative Regulation Of Viral Transcription Blood Coagulation Hemostasis CENP-A Containing Nucleosome Assembly Histone H3 Deacetylation Regulation Of Cell Death RNA Metabolic Process Tongue Development Histone Exchange DNA Replication-independent Nucleosome Assembly Epithelial Cell Differentiation Gene Expression Regulation Of Body Fluid Levels
Tagcloud ?		adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Difference) ?		adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Intersection) ?