BRMS1 and SUDS3

Number of citations of the paper that reports this interaction (PMID 14581478)
52

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		BRMS1	SUDS3
Gene Name		breast cancer metastasis suppressor 1	suppressor of defective silencing 3 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nucleus Nucleoplasm Cytoplasm Sin3 Complex Sin3-type Complex
	Molecular Function	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Histone Deacetylase Activity Protein Binding Enzyme Binding Protein Homodimerization Activity Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Apoptotic Process Gene Expression Histone Deacetylation Substantia Nigra Development Regulation Of Gene Expression, Epigenetic Positive Regulation Of Apoptotic Process Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones	NoRC negatively regulates rRNA expression Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Hemostatic factors and hematological phenotypes ( 22443383)
Protein-Protein Interactions		36 interactors: APP ARID4A BRMS1L CEP70 DNAJB1 DNAJB6 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 ING1 KPNA5 LINC00152 LRIF1 NMI PFDN5 RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNX6 SPOP SUDS3 TAF1 UBE2D1	4 interactors: BRMS1 CSNK2A1 HDAC1 SRPK1
Entrez ID		25855	64426
HPRD ID		05879	12196
Ensembl ID		ENSG00000174744	ENSG00000111707
Uniprot IDs		G5E9I4 Q9HCU9	Q9H7L9
PDB IDs		2XUS 4AUV
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Modification Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Protein Deacetylation Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Histone H3-K9 Modification Chromosome Organization Negative Regulation Of Biosynthetic Process Histone Modification Negative Regulation Of Cellular Metabolic Process Organelle Organization Negative Regulation Of Gene Expression, Epigenetic Histone H4 Deacetylation Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Histone H3 Deacetylation Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Gene Expression Cellular Response To Heat Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromatin Remodeling Positive Regulation Of Macromolecule Biosynthetic Process Response To Heat Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process ATP-dependent Chromatin Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process	Histone Deacetylation Protein Deacetylation Negative Regulation Of Viral Process Chromatin Organization Regulation Of Viral Process Chromosome Organization RNA Metabolic Process Cellular Protein Modification Process Gene Expression Positive Regulation Of Anoikis Regulation Of Apoptotic Process Rhythmic Process Regulation Of Cell Death Cellular Protein Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Sperm Chromatin Condensation Histone Modification Positive Regulation Of Receptor Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation By Host Of Viral Transcription Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cell Cycle Fungiform Papilla Formation Negative Regulation Of Androgen Receptor Signaling Pathway Fungiform Papilla Morphogenesis Negative Regulation Of Cellular Metabolic Process Fungiform Papilla Development Regulation Of Receptor Biosynthetic Process Eyelid Development In Camera-type Eye Nitrogen Compound Metabolic Process Protein Metabolic Process Regulation Of Anoikis Viral Process Hair Follicle Placode Formation Transcription, DNA-templated Tongue Morphogenesis Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Viral Transcription Positive Regulation Of Viral Genome Replication Chromatin Modification RNA Biosynthetic Process Histone H4 Deacetylation Positive Regulation Of Protein Deacetylation Spermatid Nucleus Differentiation Interaction With Symbiont Mitotic Cell Cycle
Tagcloud ?		adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Difference) ?		adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Intersection) ?