BRMS1 and SNX6

Number of citations of the paper that reports this interaction (PMID 20830743)
2

Data Source:
BioGRID (fluorescent resonance energy transfer)

		BRMS1	SNX6
Gene Name		breast cancer metastasis suppressor 1	sorting nexin 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Intracellular Nucleus Cytoplasm Cytoplasmic Membrane-bounded Vesicle Extrinsic Component Of Membrane Retromer Complex Early Endosome Membrane Tubular Endosome
	Molecular Function	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Protein Binding Dynactin Binding Phosphatidylinositol Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Intracellular Protein Transport Endocytosis Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Vesicle Organization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Retrograde Transport, Endosome To Golgi Negative Regulation Of Transcription, DNA-templated Regulation Of Histamine Secretion By Mast Cell
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		36 interactors: APP ARID4A BRMS1L CEP70 DNAJB1 DNAJB6 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 ING1 KPNA5 LINC00152 LRIF1 NMI PFDN5 RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNX6 SPOP SUDS3 TAF1 UBE2D1	22 interactors: ACVR2B ACVRL1 BMPR1B BRCA1 BRMS1 CALM1 COIL CSNK2A2 DISC1 EGFR INSR LEPR NDEL1 PDGFRA PIM1 SNX1 SNX2 SNX4 TGFBR1 TGFBR2 TNIK TPT1
Entrez ID		25855	58533
HPRD ID		05879	12086
Ensembl ID		ENSG00000174744	ENSG00000129515
Uniprot IDs		G5E9I4 Q9HCU9	B4DJS7 Q9UNH7
PDB IDs		2XUS 4AUV
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Modification Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Protein Deacetylation Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Histone H3-K9 Modification Chromosome Organization Negative Regulation Of Biosynthetic Process Histone Modification Negative Regulation Of Cellular Metabolic Process Organelle Organization Negative Regulation Of Gene Expression, Epigenetic Histone H4 Deacetylation Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Histone H3 Deacetylation Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Gene Expression Cellular Response To Heat Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromatin Remodeling Positive Regulation Of Macromolecule Biosynthetic Process Response To Heat Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process ATP-dependent Chromatin Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process	Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction By Phosphorylation Regulation Of Signaling Developmental Process Positive Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Transferase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Phosphorylation Positive Regulation Of Metabolic Process Anatomical Structure Development Phosphorylation Intracellular Signal Transduction Regulation Of Kinase Activity Positive Regulation Of Cellular Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Development Regulation Of Phosphorylation Activation Of Protein Kinase Activity Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Anatomical Structure Morphogenesis Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Cell Surface Receptor Signaling Pathway Regulation Of Cell Differentiation Cellular Protein Modification Process Cellular Response To Growth Factor Stimulus Regulation Of Metabolic Process Sensory Organ Development Camera-type Eye Development Response To Growth Factor Positive Regulation Of Signal Transduction Retina Vasculature Development In Camera-type Eye Eye Development Phosphate-containing Compound Metabolic Process Protein Autophosphorylation Regulation Of Catalytic Activity Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cell Proliferation Palate Development Activin Receptor Signaling Pathway Chordate Embryonic Development Embryo Development
Tagcloud ?		adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Difference) ?		adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Intersection) ?