HAP1 and TIMM17A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		HAP1	TIMM17A
Description		huntingtin associated protein 1	translocase of inner mitochondrial membrane 17A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Mitochondrion Lysosome Endosome Early Endosome Autophagosome Endoplasmic Reticulum Centrosome Centriole Cytosol Cytoskeleton Synaptic Vesicle Actin Cytoskeleton Inclusion Body Axon Dendrite Growth Cone Cytoplasmic Vesicle Cell Projection Neuron Projection Dendritic Spine Synapse Presynapse Axon Cytoplasm	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Myosin Binding Transmembrane Transporter Binding Brain-derived Neurotrophic Factor Binding	Protein Transmembrane Transporter Activity
	Biological Process	Protein Targeting Exocytosis Autophagy Chemical Synaptic Transmission Brain Development Anterograde Axonal Transport Retrograde Axonal Transport Intracellular Protein Localization Protein Transport Regulation Of Exocytosis Cerebellum Development Hypothalamus Cell Differentiation Neurogenesis Cell Projection Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of Neurotrophin Production Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vesicle Transport Along Microtubule Neurotrophin TRK Receptor Signaling Pathway Mitochondrion Distribution Positive Regulation Of Neurogenesis Negative Regulation Of Amyloid-beta Formation Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Non-motile Cilium Assembly	Protein Targeting To Mitochondrion Intracellular Protein Transport Protein Transport Protein Import Into Mitochondrial Matrix
Pathways			Mitochondrial protein import Mitochondrial protein import Mitochondrial protein degradation
Drugs
Diseases
GWAS		Developmental language disorder (syntactic complexity) ( 27016271) Esophageal cancer (squamous cell) ( 22960999)
Interacting Genes		93 interacting genes: AEN ANTKMT APLP1 ATP5MF BARD1 BRD7 C1orf216 C7orf25 C8orf33 CATSPERT CBX8 CCDC13 CDC73 CDK18 CDK5RAP2 CFAP263 COL9A2 CRIP1 DCTN1 DDX49 DEFB1 EIF3E FAM50B FEZ1 GABARAPL2 GADD45G GIT1 GPRASP2 HDAC4 HGS HMOX2 HOXB5 HSPA1A HSPA4 HTT IMMT ING5 KAT5 KAT7 KATNBL1 KBTBD7 KPNA2 LRIF1 LUC7L2 MPP3 MRPS9 MSGN1 NAP1L5 NDUFB9 NEUROD1 NIPSNAP3A NOD2 NOP53 PABPC4 PCM1 PDCD7 PFDN1 PKN1 PPID PPOX PPP1R18 PRPF31 PSMD11 RER1 RHPN1 RIF1 RPS10 RPS25 SCNM1 SNAPIN SRSF4 STX5 TAF1D TBP TIMM17A TNNT1 TNNT3 TOMM20 TSPYL1 UTP3 VIM ZFP1 ZMAT2 ZNF124 ZNF20 ZNF24 ZNF33B ZNF490 ZNF572 ZNF575 ZNF648 ZNF691 ZNF835	3 interacting genes: HAP1 TIMM44 TUBA1A
Entrez ID		9001	10440
HPRD ID		02972	05449
Ensembl ID		ENSG00000173805	ENSG00000134375
Uniprot IDs		P54257	Q99595
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Nucleoplasm Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Microtubule Nucleation Positive Regulation Of Microtubule Polymerization Regulation Of Primary Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Establishment Of Mitotic Spindle Localization Establishment Of Mitotic Spindle Orientation Mitotic Spindle Pole DNA Replication-dependent Chromatin Disassembly Establishment Of Spindle Orientation Regulation Of Microtubule Nucleation Chromatin Organization Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Protein Binding Regulation Of Metabolic Process Establishment Of Spindle Localization Positive Regulation Of Aggrephagy Protein Import Into Mitochondrial Matrix RNA Polymerase Transcription Factor SL1 Complex Histone Acetyltransferase Complex Spindle Localization Regulation Of Microtubule Polymerization Regulation Of Macromolecule Metabolic Process Establishment Of Organelle Localization Centriolar Satellite Male Pronucleus Troponin Complex Protein Acetylation Histone H4K16 Acetyltransferase Activity Gamma-tubulin Binding	Cellular Localization Protein Transport Establishment Of Protein Localization Microtubule-based Transport Establishment Of Organelle Localization Transport Along Microtubule Neurogenesis Establishment Of Localization In Cell Intracellular Transport Cytoskeleton-dependent Intracellular Transport Organelle Transport Along Microtubule Brain-derived Neurotrophic Factor Binding Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Protein Targeting Positive Regulation Of Neurotrophin Production Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Pyramidal Neuron Differentiation Cerebellar Cortex Morphogenesis Hypothalamus Cell Differentiation Intracellular Protein Localization Forebrain Morphogenesis Microtubule-based Movement Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Non-motile Cilium Assembly Organelle Localization Regulation Of Non-motile Cilium Assembly Locomotory Exploration Behavior Neurotrophin TRK Receptor Signaling Pathway Intracellular Protein Transport Positive Regulation Of Synaptic Transmission, GABAergic TIM23 Mitochondrial Import Inner Membrane Translocase Complex Response To L-glutamate Startle Response Inclusion Body Mitochondrion Distribution Neuron Projection Arborization Microtubule Polymerization Retrograde Axonal Transport Negative Regulation Of Amyloid-beta Formation Myosin Binding Positive Regulation Of Cation Channel Activity Protein Import Into Mitochondrial Matrix Dentate Gyrus Development Motor Behavior Neurotrophin Signaling Pathway Negative Regulation Of Amyloid Precursor Protein Catabolic Process Protein Targeting To Mitochondrion Condensed Chromosome Axonemal Microtubule Exploration Behavior
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