HAP1 and C7orf25

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		HAP1	C7orf25
Description		huntingtin associated protein 1	chromosome 7 open reading frame 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Mitochondrion Lysosome Endosome Early Endosome Autophagosome Endoplasmic Reticulum Centrosome Centriole Cytosol Cytoskeleton Synaptic Vesicle Actin Cytoskeleton Inclusion Body Axon Dendrite Growth Cone Cytoplasmic Vesicle Cell Projection Neuron Projection Dendritic Spine Synapse Presynapse Axon Cytoplasm
	Molecular Function	Signaling Receptor Binding Protein Binding Myosin Binding Transmembrane Transporter Binding Brain-derived Neurotrophic Factor Binding	Protein Binding
	Biological Process	Protein Targeting Exocytosis Autophagy Chemical Synaptic Transmission Brain Development Anterograde Axonal Transport Retrograde Axonal Transport Intracellular Protein Localization Protein Transport Regulation Of Exocytosis Cerebellum Development Hypothalamus Cell Differentiation Neurogenesis Cell Projection Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of Neurotrophin Production Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vesicle Transport Along Microtubule Neurotrophin TRK Receptor Signaling Pathway Mitochondrion Distribution Positive Regulation Of Neurogenesis Negative Regulation Of Amyloid-beta Formation Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Non-motile Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Developmental language disorder (syntactic complexity) ( 27016271) Esophageal cancer (squamous cell) ( 22960999)	Asthma ( 29273806) Ceramide levels (C24:0) ( 32489964)
Interacting Genes		93 interacting genes: AEN ANTKMT APLP1 ATP5MF BARD1 BRD7 C1orf216 C7orf25 C8orf33 CATSPERT CBX8 CCDC13 CDC73 CDK18 CDK5RAP2 CFAP263 COL9A2 CRIP1 DCTN1 DDX49 DEFB1 EIF3E FAM50B FEZ1 GABARAPL2 GADD45G GIT1 GPRASP2 HDAC4 HGS HMOX2 HOXB5 HSPA1A HSPA4 HTT IMMT ING5 KAT5 KAT7 KATNBL1 KBTBD7 KPNA2 LRIF1 LUC7L2 MPP3 MRPS9 MSGN1 NAP1L5 NDUFB9 NEUROD1 NIPSNAP3A NOD2 NOP53 PABPC4 PCM1 PDCD7 PFDN1 PKN1 PPID PPOX PPP1R18 PRPF31 PSMD11 RER1 RHPN1 RIF1 RPS10 RPS25 SCNM1 SNAPIN SRSF4 STX5 TAF1D TBP TIMM17A TNNT1 TNNT3 TOMM20 TSPYL1 UTP3 VIM ZFP1 ZMAT2 ZNF124 ZNF20 ZNF24 ZNF33B ZNF490 ZNF572 ZNF575 ZNF648 ZNF691 ZNF835	20 interacting genes: BRD4 CEP70 CRYM DACT1 EZH2 FRA10AC1 FYN FZR1 GTPBP1 HAP1 HEXD MTOR MX1 NGEF PTN RASSF1 RPL36AL SF3B2 TARS1 UBE2D1
Entrez ID		9001	79020
HPRD ID		02972	09861
Ensembl ID		ENSG00000173805	ENSG00000136197
Uniprot IDs		P54257	Q9BPX7
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Nucleoplasm Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Microtubule Nucleation Positive Regulation Of Microtubule Polymerization Regulation Of Primary Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Establishment Of Mitotic Spindle Localization Establishment Of Mitotic Spindle Orientation Mitotic Spindle Pole DNA Replication-dependent Chromatin Disassembly Establishment Of Spindle Orientation Regulation Of Microtubule Nucleation Chromatin Organization Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Protein Binding Regulation Of Metabolic Process Establishment Of Spindle Localization Positive Regulation Of Aggrephagy Protein Import Into Mitochondrial Matrix RNA Polymerase Transcription Factor SL1 Complex Histone Acetyltransferase Complex Spindle Localization Regulation Of Microtubule Polymerization Regulation Of Macromolecule Metabolic Process Establishment Of Organelle Localization Centriolar Satellite Male Pronucleus Troponin Complex Protein Acetylation Histone H4K16 Acetyltransferase Activity Gamma-tubulin Binding	Regulation Of Plasma Membrane Bounded Cell Projection Organization Negative Regulation Of Intracellular Signal Transduction Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Projection Organization Regulation Of Protein Metabolic Process Positive Regulation Of Dendrite Development Regulation Of Cell Projection Organization Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Metabolic Process Regulation Of Gliogenesis Positive Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Protein Ubiquitination Cytoplasmic Translation Ephrin Receptor Binding Positive Regulation Of Post-translational Protein Modification Delta1-piperideine-2-carboxylate Reductase Activity Nucleus Thiomorpholine-carboxylate Dehydrogenase Activity Regulation Of Cellular Component Organization Positive Regulation Of Neuron Projection Development Positive Regulation Of Protein Modification Process Hepatocyte Homeostasis Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Modification Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Neurogenesis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Translation Transmembrane Transporter Binding Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Glial Cell Differentiation Regulation Of Protein Catabolic Process Pyrimidine-containing Compound Biosynthetic Process Regulation Of Oligodendrocyte Differentiation Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Cellular Response To Glycine Response To Singlet Oxygen Positive Regulation Of Neurotrophin Production Histone H4K8ac Reader Activity Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Myelination T Cell Costimulation Regulation Of Cell Cycle Process Regulation Of Neuron Projection Development Cellular Response To Stress Regulation Of Nervous System Development Positive Regulation Of Cell Development Dendrite Morphogenesis Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
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