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ITGB3BP and THRA
Number of citations of the paper that reports this interaction (PMID
10490654
)
16
Data Source:
BioGRID
(pull down)
ITGB3BP
THRA
Gene Name
integrin beta 3 binding protein (beta3-endonexin)
thyroid hormone receptor, alpha
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Condensed Chromosome Kinetochore
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Nucleus
Nucleoplasm
Cytosol
Molecular Function
Signal Transducer Activity
Protein C-terminus Binding
Steroid Receptor RNA Activator RNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Steroid Hormone Receptor Activity
Thyroid Hormone Receptor Activity
Protein Binding
Transcription Factor Binding
Zinc Ion Binding
TBP-class Protein Binding
Protein Domain Specific Binding
Chromatin DNA Binding
Protein Complex Binding
Sequence-specific DNA Binding
Transcription Regulatory Region DNA Binding
Thyroid Hormone Binding
Biological Process
Mitotic Cell Cycle
Nucleosome Assembly
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Mitotic Nuclear Division
Cell Adhesion
Signal Transduction
CENP-A Containing Nucleosome Assembly
Positive Regulation Of Apoptotic Process
Neurotrophin TRK Receptor Signaling Pathway
Cell Division
Apoptotic Signaling Pathway
Cartilage Condensation
Ossification
Regulation Of Thyroid Hormone Mediated Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Learning Or Memory
Regulation Of Heart Contraction
Female Courtship Behavior
Response To Cold
Hormone-mediated Signaling Pathway
Gene Expression
Positive Regulation Of Myotube Differentiation
Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Erythrocyte Differentiation
Intracellular Receptor Signaling Pathway
Thyroid Gland Development
Regulation Of Myeloid Cell Apoptotic Process
Cytoplasmic Sequestering Of Transcription Factor
Steroid Hormone Mediated Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Female Receptivity
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Lipid Catabolic Process
Type I Pneumocyte Differentiation
Negative Regulation Of DNA-templated Transcription, Initiation
Pathways
Mitotic Prometaphase
Signalling by NGF
Chromosome Maintenance
Cell death signalling via NRAGE, NRIF and NADE
Separation of Sister Chromatids
Deposition of new CENPA-containing nucleosomes at the centromere
p75 NTR receptor-mediated signalling
Mitotic Anaphase
M Phase
Cell Cycle, Mitotic
Nucleosome assembly
NRIF signals cell death from the nucleus
Resolution of Sister Chromatid Cohesion
Mitotic Metaphase and Anaphase
Generic Transcription Pathway
Nuclear Receptor transcription pathway
Drugs
Liothyronine
Levothyroxine
Dextrothyroxine
Liotrix
3,5-Dichloro-4-[(4-Hydroxy-3-Isopropylphenoxy)Phenylacetic Acid
Diseases
GWAS
White blood cell count (
21738480
)
Protein-Protein Interactions
21 interactors:
ACTN2
APP
ARFIP2
CCNA2
COL4A3BP
DDX24
ESR1
ITGB3
ITGB5
KDM1A
KIFC3
MAPK6
MTA1
NFKB1
PIH1D2
RECQL5
RXRA
RXRG
SVIL
THRA
UBR7
56 interactors:
AKAP13
AMOTL2
ARID5A
BTG1
BUB3
C1D
CCND1
CDK7
CLIC1
COPS2
CREB1
CREBBP
CUL1
DAP3
ESR1
FOXJ1
FUS
GRIP1
GTF2B
HDAC2
HDAC3
ITGB3BP
L3MBTL3
MED1
MED21
MED25
MEF2A
NCOA1
NCOA6
NCOR1
NCOR2
NR0B2
NR2F1
NRIP1
NSD1
OASL
PML
POU2F1
PRKDC
PTGES3
RANBP9
RGN
RXRA
RXRB
RXRG
SEPP1
SLC16A2
SRC
SUV39H1
TBL1X
TDG
TRIM24
TRIP11
YWHAH
YWHAQ
ZBTB3
Entrez ID
23421
7067
HPRD ID
09267
07185
Ensembl ID
ENSG00000142856
ENSG00000126351
Uniprot IDs
Q13352
P10827
Q6FH41
PDB IDs
1NAV
2H77
2H79
3HZF
3ILZ
3JZB
Enriched GO Terms of Interacting Partners
?
Intracellular Receptor Signaling Pathway
Steroid Hormone Mediated Signaling Pathway
Response To Lipid
Hormone-mediated Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Positive Regulation Of Cellular Metabolic Process
Signaling
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Response To Organic Cyclic Compound
Positive Regulation Of Gene Expression
Cell Communication
Cellular Response To Lipid
Regulation Of Branching Involved In Prostate Gland Morphogenesis
Positive Regulation Of Cellular Biosynthetic Process
Protein Homotetramerization
Platelet Degranulation
DNA-templated Transcription, Initiation
Response To Steroid Hormone
Response To Stimulus
Signal Transduction
Response To Organic Cyclic Compound
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
Organelle Organization
Response To Hormone
Cellular Response To Hormone Stimulus
Protein Tetramerization
Cellular Response To Stimulus
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Response To Stress
Negative Regulation Of Lipid Transport
Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Retinoic Acid Receptor Signaling Pathway
Negative Regulation Of Transport
Regulation Of RNA Metabolic Process
Mating Behavior
Tissue Development
Organ Development
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Blood Coagulation
Cell-matrix Adhesion
Hemostasis
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Gene Expression
Regulation Of Transcription, DNA-templated
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Regulation Of Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Intracellular Receptor Signaling Pathway
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
DNA-templated Transcription, Initiation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Nitrogen Compound Metabolic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Rhythmic Process
Organ Development
Multicellular Organismal Development
Regulation Of Cellular Process
Anatomical Structure Development
Developmental Process
Cellular Response To Organic Substance
Signal Transduction
Chromosome Organization
Signaling
System Development
Tagcloud
?
accounts
averages
bimodality
bxd
bxh
chr
counted
encode
ganglion
heritable
hoxb
idea
inbred
krt1
lod
mapped
neuregulin
nnc1
opposed
qtl
qtls
retina
retinal
striking
subsidiary
surprisingly
thyroxine
trait
vertebrate
Tagcloud (Difference)
?
accounts
averages
bimodality
bxd
bxh
chr
counted
encode
ganglion
heritable
hoxb
idea
inbred
krt1
lod
mapped
neuregulin
nnc1
opposed
qtl
qtls
retina
retinal
striking
subsidiary
surprisingly
thyroxine
trait
vertebrate
Tagcloud (Intersection)
?