ITGB3BP and SNAPC5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ITGB3BP	SNAPC5
Description		integrin subunit beta 3 binding protein	small nuclear RNA activating complex polypeptide 5
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Membrane	Nucleus Nucleoplasm Nucleolus Nuclear Body
	Molecular Function	Protein Binding	RNA Polymerase III General Transcription Initiation Factor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	Regulation Of DNA-templated Transcription Apoptotic Process Chromosome Segregation Cell Adhesion Signal Transduction CENP-A Containing Chromatin Assembly Positive Regulation Of Epithelial Cell Proliferation Cell Division Negative Regulation Of Epithelial Cell Apoptotic Process	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494)
Interacting Genes		42 interacting genes: ACTN2 ANKRD11 APP ARFIP2 C14orf119 CCNA2 CERT1 DDX24 EFHC1 ESR1 GTPBP3 HSF2BP ITGB3 ITGB5 KDM1A KIAA0930 KIFC3 LRRK2 MAPK6 MAPK9 MEIS2 MEOX2 MSGN1 MTA1 NFKB1 NRDE2 NTAQ1 PBX3 PIH1D2 PIK3R3 PKNOX1 RECQL5 RXRA RXRG SNAPC5 SUOX SVIL THRA TRIML2 UBR7 USHBP1 USP20	43 interacting genes: AMOT ARHGEF38 BATF BFSP2 BLOC1S1 BRCC3 CBY2 CCDC196 CDCA8 CREB5 CREBBP CYTH1 CYTH4 DDIT3 EMILIN1 FAM9C GALR1 GORAB GRIPAP1 HMG20B ITGB3BP JUN LMO2 MBD3L1 MCRS1 MYF5 NDEL1 NMI NOL4 NUDT10 NUP62 POLR2J RNF4 S100Z SNAPC1 SNAPC4 STMN4 TRAPPC2 TRAPPC2B TXLNB ZNF177 ZNF559-ZNF177 ZNRD2
Entrez ID		23421	10302
HPRD ID		09267	16183
Ensembl ID		ENSG00000142856	ENSG00000174446
Uniprot IDs		Q13352	O75971
PDB IDs		7PB8 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH	7ZWC 7ZWD 7ZX7 7ZX8 7ZXE
Enriched GO Terms of Interacting Partners?		Sequence-specific DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-templated Transcription Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Transcription Regulator Complex DNA-binding Transcription Factor Activity NF-kappaB P50/p65 Complex Positive Regulation Of Transcription By RNA Polymerase II Nuclear Receptor Activity Transcription By RNA Polymerase II Chromatin Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Positive Regulation Of Protein Autoubiquitination Nuclear Steroid Receptor Activity Chromatin Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Retinoic Acid Receptor Signaling Pathway RNA Metabolic Process Hormone-mediated Signaling Pathway Negative Regulation Of MiRNA Transcription Intracellular Signaling Cassette Cellular Response To Oxygen-containing Compound Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Identical Protein Binding Regulation Of MiRNA Metabolic Process Regulation Of Macrophage Derived Foam Cell Differentiation Nucleic Acid Metabolic Process Intracellular Signal Transduction Regulation Of Thyroid Hormone Receptor Signaling Pathway Regulation Of Protein Autoubiquitination Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Retinoic Acid-responsive Element Binding Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of RNA Metabolic Process Response To Mechanical Stimulus Positive Regulation Of Protein Ubiquitination Cellular Response To Nicotine Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Cellular Response To Manganese Ion Intracellular Receptor Signaling Pathway	SnRNA-activating Protein Complex Peptidyl-lysine Acetylation Protein Binding Integrated Stress Response Signaling RNA Polymerase II Transcription Regulator Complex CAMP Response Element Binding TRAPPII Protein Complex TRAPPIII Protein Complex SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity Positive Regulation Of Mitotic Cytokinesis Centrosome Separation Mitotic Centrosome Separation SnRNA Transcription Regulation Of Mitotic Cytokinesis
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